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Jacob S Brenner
Jacob S Brenner
Depts. of Medicine & Pharmacology, University of Pennsylvania
Verified email at pennmedicine.upenn.edu - Homepage
Title
Cited by
Cited by
Year
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude
JS Brenner, DC Pan, JW Myerson, OA Marcos-Contreras, CH Villa, ...
Nature communications 9 (1), 2684, 2018
3862018
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E …
H Parhiz, VV Shuvaev, N Pardi, M Khoshnejad, RY Kiseleva, JS Brenner, ...
Journal of controlled release 291, 106-115, 2018
2272018
Closure device and method
JS Brenner, GA Magee, RF PEH, EI Palmer
US Patent 9,232,947, 2016
2152016
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier
OA Marcos-Contreras, CF Greineder, RY Kiseleva, H Parhiz, LR Walsh, ...
Proceedings of the National Academy of Sciences 117 (7), 3405-3414, 2020
1872020
Nanoparticle properties modulate their attachment and effect on carrier red blood cells
DC Pan, JW Myerson, JS Brenner, PN Patel, AC Anselmo, S Mitragotri, ...
Scientific Reports 8 (1), 1615, 2018
1442018
Targeting drug delivery in the vascular system: Focus on endothelium
PM Glassman, JW Myerson, LT Ferguson, RY Kiseleva, VV Shuvaev, ...
Advanced drug delivery reviews 157, 96-117, 2020
1432020
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE)
H Parhiz, JS Brenner, PN Patel, TE Papp, H Shahnawaz, Q Li, R Shi, ...
Journal of Controlled Release 344, 50-61, 2022
1352022
Red blood cell hitchhiking: a novel approach for vascular delivery of nanocarriers
JS Brenner, S Mitragotri, VR Muzykantov
Annual review of biomedical engineering 23 (1), 225-248, 2021
1282021
Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation
JW Myerson, PN Patel, KM Rubey, ME Zamora, MH Zaleski, N Habibi, ...
Nature nanotechnology 17 (1), 86-97, 2022
1122022
Vascular drug delivery using carrier red blood cells: focus on RBC surface loading and pharmacokinetics
PM Glassman, CH Villa, A Ukidve, Z Zhao, P Smith, S Mitragotri, ...
Pharmaceutics 12 (5), 440, 2020
1112020
Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers
PM Glassman, ED Hood, LT Ferguson, Z Zhao, DL Siegel, S Mitragotri, ...
Advanced drug delivery reviews 178, 113992, 2021
972021
Physicochemical targeting of lipid nanoparticles to the lungs induces clotting: mechanisms and solutions
S Omo‐Lamai, ME Zamora, MN Patel, J Wu, J Nong, Z Wang, A Peshkova, ...
Advanced Materials 36 (26), 2312026, 2024
862024
Unintended effects of drug carriers: Big issues of small particles
H Parhiz, M Khoshnejad, JW Myerson, E Hood, PN Patel, JS Brenner, ...
Advanced drug delivery reviews 130, 90-112, 2018
802018
Neutrophils promote alveolar epithelial regeneration by enhancing type II pneumocyte proliferation in a model of acid-induced acute lung injury
AJ Paris, Y Liu, J Mei, N Dai, L Guo, LA Spruce, KM Hudock, JS Brenner, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (6 …, 2016
732016
TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size
JS Brenner, RE Dolmetsch
PloS one 2 (8), e802, 2007
702007
Mechanisms and barriers in nanomedicine: progress in the field and future directions
T Anchordoquy, N Artzi, IV Balyasnikova, Y Barenholz, NM La-Beck, ...
ACS nano 18 (22), 13983-13999, 2024
642024
Targeted endothelial nanomedicine for common acute pathological conditions
VV Shuvaev, JS Brenner, VR Muzykantov
Journal of Controlled Release 219, 576-595, 2015
602015
Endothelial nanomedicine for the treatment of pulmonary disease
JS Brenner, C Greineder, V Shuvaev, V Muzykantov
Expert opinion on drug delivery 12 (2), 239-261, 2015
602015
Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain
OA Marcos-Contreras, JS Brenner, RY Kiseleva, V Zuluaga-Ramirez, ...
Journal of controlled release 301, 54-61, 2019
592019
Combating complement's deleterious effects on nanomedicine by conjugating complement regulatory proteins to nanoparticles
Z Wang, ED Hood, J Nong, J Ding, OA Marcos‐Contreras, PM Glassman, ...
Advanced Materials 34 (8), 2107070, 2022
582022
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