| Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude JS Brenner, DC Pan, JW Myerson, OA Marcos-Contreras, CH Villa, ... Nature communications 9 (1), 2684, 2018 | 386 | 2018 |
| Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier OA Marcos-Contreras, CF Greineder, RY Kiseleva, H Parhiz, LR Walsh, ... Proceedings of the National Academy of Sciences 117 (7), 3405-3414, 2020 | 187 | 2020 |
| Hyperfibrinolysis increases blood–brain barrier permeability by a plasmin-and bradykinin-dependent mechanism OA Marcos-Contreras, S Martinez de Lizarrondo, I Bardou, C Orset, ... Blood, The Journal of the American Society of Hematology 128 (20), 2423-2434, 2016 | 169 | 2016 |
| Ultra-sensitive molecular MRI of vascular cell adhesion molecule-1 reveals a dynamic inflammatory penumbra after strokes M Gauberti, A Montagne, OA Marcos-Contreras, A Le Béhot, E Maubert, ... Stroke 44 (7), 1988-1996, 2013 | 138 | 2013 |
| Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE) H Parhiz, JS Brenner, PN Patel, TE Papp, H Shahnawaz, Q Li, R Shi, ... Journal of Controlled Release 344, 50-61, 2022 | 135 | 2022 |
| Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation S Zaitsev, D Spitzer, JC Murciano, BS Ding, S Tliba, MA Kowalska, ... Blood, The Journal of the American Society of Hematology 115 (25), 5241-5248, 2010 | 127 | 2010 |
| Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation JW Myerson, PN Patel, KM Rubey, ME Zamora, MH Zaleski, N Habibi, ... Nature nanotechnology 17 (1), 86-97, 2022 | 112 | 2022 |
| Flexible nanoparticles reach sterically obscured endothelial targets inaccessible to rigid nanoparticles JW Myerson, B Braender, O Mcpherson, PM Glassman, RY Kiseleva, ... Advanced Materials 30 (32), 1802373, 2018 | 105 | 2018 |
| Physicochemical targeting of lipid nanoparticles to the lungs induces clotting: mechanisms and solutions S Omo‐Lamai, ME Zamora, MN Patel, J Wu, J Nong, Z Wang, A Peshkova, ... Advanced Materials 36 (26), 2312026, 2024 | 86 | 2024 |
| Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain OA Marcos-Contreras, JS Brenner, RY Kiseleva, V Zuluaga-Ramirez, ... Journal of controlled release 301, 54-61, 2019 | 59 | 2019 |
| Combating complement's deleterious effects on nanomedicine by conjugating complement regulatory proteins to nanoparticles Z Wang, ED Hood, J Nong, J Ding, OA Marcos‐Contreras, PM Glassman, ... Advanced Materials 34 (8), 2107070, 2022 | 58 | 2022 |
| Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke J Nong, PM Glassman, VV Shuvaev, S Reyes-Esteves, HC Descamps, ... Molecular Therapy 32 (5), 1344-1358, 2024 | 55 | 2024 |
| Dual affinity to RBCs and target cells (DART) enhances both organ-and cell type-targeting of intravascular nanocarriers LT Ferguson, ED Hood, T Shuvaeva, VV Shuvaev, MC Basil, Z Wang, ... ACS nano 16 (3), 4666-4683, 2022 | 51 | 2022 |
| Lipid nanoparticle-associated inflammation is triggered by sensing of endosomal damage: engineering endosomal escape without side effects S Omo-Lamai, Y Wang, MN Patel, EO Essien, M Shen, A Majumdar, ... BioRxiv, 2024.04. 16.589801, 2024 | 50 | 2024 |
| Cross-linker-modulated nanogel flexibility correlates with tunable targeting to a sterically impeded endothelial marker JW Myerson, O McPherson, KG DeFrates, JH Towslee, ... ACS nano 13 (10), 11409-11421, 2019 | 39 | 2019 |
| Molecularly engineered nanobodies for tunable pharmacokinetics and drug delivery PM Glassman, LR Walsh, CH Villa, OA Marcos-Contreras, ED Hood, ... Bioconjugate chemistry 31 (4), 1144-1155, 2020 | 38 | 2020 |
| Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9 M Khoshnejad, JS Brenner, W Motley, H Parhiz, CF Greineder, CH Villa, ... Scientific reports 8 (1), 1760, 2018 | 38 | 2018 |
| Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII OA Marcos-Contreras, SM Smith, DA Bellinger, RA Raymer, E Merricks, ... Blood, The Journal of the American Society of Hematology 127 (5), 565-571, 2016 | 34 | 2016 |
| The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo G Pavani, L Ivanciu, A Faella, OA Marcos-Contreras, P Margaritis Blood, The Journal of the American Society of Hematology 124 (7), 1157-1165, 2014 | 34 | 2014 |
| Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage S Reyes-Esteves, J Nong, PM Glassman, S Omo-Lamai, S Ohashi, ... Journal of Controlled Release 356, 185-195, 2023 | 31 | 2023 |
Maxime GaubertiINSERM U1237Verified email at cyceron.fr
