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Thomas Durcan
Thomas Durcan
The Neuro's Early Drug Discovery Unit (EDDU), McGill University
Verified email at mcgill.ca - Homepage
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
9629*2021
Guidelines for the use and interpretation of assays for monitoring autophagy 1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1, 2021
41662021
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Taylor and Francis, 2016
2255*2016
The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications
TM Durcan, EA Fon
Genes & development 29 (10), 989-999, 2015
4662015
USP 8 regulates mitophagy by removing K 6‐linked ubiquitin conjugates from parkin
TM Durcan, MY Tang, JR Pérusse, EA Dashti, MA Aguileta, GL McLelland, ...
The EMBO journal 33 (21), 2473-2491, 2014
4582014
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
GL McLelland, T Goiran, W Yi, G Dorval, CX Chen, ND Lauinger, AI Krahn, ...
Elife 7, e32866, 2018
4132018
Guidelines for the use and interpretation of assays for monitoring autophagy
K Dj, D Cervia
397*2016
The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
TM Durcan, M Kontogiannea, T Thorarinsdottir, L Fallon, AJ Williams, ...
Human molecular genetics 20 (1), 141-154, 2011
1892011
Defending the mitochondria: the pathways of mitophagy and mitochondrial-derived vesicles
RF Roberts, MY Tang, EA Fon, TM Durcan
The international journal of biochemistry & cell biology 79, 427-436, 2016
1362016
Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
C Laflamme, PM McKeever, R Kumar, J Schwartz, M Kolahdouzan, ...
Elife 8, e48363, 2019
1262019
Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme
TM Durcan, M Kontogiannea, N Bedard, SS Wing, EA Fon
Journal of Biological Chemistry 287 (1), 531-541, 2012
1022012
The neglected genes of ALS: Cytoskeletal dynamics impact synaptic degeneration in ALS
MJ Castellanos-Montiel, M Chaineau, TM Durcan
Frontiers in cellular neuroscience 14, 594975, 2020
922020
A Multistep Workflow to Evaluate Newly Generated iPSCs and Their Ability to Generate Different Cell Types
CXQ Chen, N Abdian, G Maussion, RA Thomas, I Demirova, E Cai, ...
Methods and Protocols 4 (3), 50, 2021
882021
Guidelines for the use and interpretation of assays for monitoring autophagy 1.
JK Daniel, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
Autophagy, 2021
872021
Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy
NV Mohamed, J Sirois, J Ramamurthy, M Mathur, P Lépine, E Deneault, ...
Brain communications 3 (4), fcab223, 2021
862021
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications
R Ayoubi, J Ryan, MS Biddle, W Alshafie, M Fotouhi, SG Bolivar, ...
Elife 12, RP91645, 2023
802023
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications
R Ayoubi, J Ryan, MS Biddle, W Alshafie, M Fotouhi, SG Bolivar, ...
Elife 12, RP91645, 2023
802023
Disruption of GRIN2B impairs differentiation in human neurons
S Bell, G Maussion, M Jefri, H Peng, JF Theroux, H Silveira, V Soubannier, ...
Stem cell reports 11 (1), 183-196, 2018
702018
Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery
V Soubannier, G Maussion, M Chaineau, V Sigutova, G Rouleau, ...
Neuroscience letters 731, 135028, 2020
672020
The Quebec Parkinson network: a researcher-patient matching platform and multimodal biorepository
Z Gan-Or, T Rao, E Leveille, C Degroot, S Chouinard, F Cicchetti, ...
Journal of Parkinson's disease 10 (1), 301-313, 2020
642020
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Articles 1–20