| Ubiquitin is phosphorylated by PINK1 to activate parkin F Koyano, K Okatsu, H Kosako, Y Tamura, E Go, M Kimura, Y Kimura, ... Nature 510 (7503), 162-166, 2014 | 1687 | 2014 |
| Structure of parkin reveals mechanisms for ubiquitin ligase activation JF Trempe, V Sauvé, K Grenier, M Seirafi, MY Tang, M Ménade, ... Science 340 (6139), 1451-1455, 2013 | 613 | 2013 |
| Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy GL McLelland, T Goiran, W Yi, G Dorval, CX Chen, ND Lauinger, AI Krahn, ... elife 7, e32866, 2018 | 413 | 2018 |
| Structural basis for Fe–S cluster assembly and tRNA thiolation mediated by IscS protein–protein interactions R Shi, A Proteau, M Villarroya, I Moukadiri, L Zhang, JF Trempe, A Matte, ... PLoS biology 8 (4), e1000354, 2010 | 324 | 2010 |
| Structure and function of the C-terminal PABC domain of human poly (A)-binding protein G Kozlov, JF Trempe, K Khaleghpour, A Kahvejian, I Ekiel, K Gehring Proceedings of the National Academy of Sciences 98 (8), 4409-4413, 2001 | 289 | 2001 |
| A Ubl/ubiquitin switch in the activation of Parkin V Sauvé, A Lilov, M Seirafi, M Vranas, S Rasool, G Kozlov, T Sprules, ... The EMBO journal 34 (20), 2492-2505, 2015 | 236 | 2015 |
| Structure and function of Parkin, PINK1, and DJ-1, the three musketeers of neuroprotection JF Trempe, EA Fon Frontiers in neurology 4, 38, 2013 | 199 | 2013 |
| Mechanism of parkin activation by phosphorylation V Sauvé, G Sung, N Soya, G Kozlov, N Blaimschein, LS Miotto, JF Trempe, ... Nature structural & molecular biology 25 (7), 623-630, 2018 | 198 | 2018 |
| PINK1 autophosphorylation is required for ubiquitin recognition S Rasool, N Soya, L Truong, N Croteau, GL Lukacs, JF Trempe EMBO reports 19 (4), e44981, 2018 | 174 | 2018 |
| SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination JF Trempe, CXQ Chen, K Grenier, EM Camacho, G Kozlov, ... Molecular cell 36 (6), 1034-1047, 2009 | 171 | 2009 |
| Structure of the complex I-like molecule NDH of oxygenic photosynthesis TG Laughlin, AN Bayne, JF Trempe, DF Savage, KM Davies Nature 566 (7744), 411-414, 2019 | 165 | 2019 |
| Specific interaction of ERp57 and calnexin determined by NMR spectroscopy and an ER two‐hybrid system S Pollock, G Kozlov, MF Pelletier, JF Trempe, G Jansen, D Sitnikov, ... The EMBO journal 23 (5), 1020-1029, 2004 | 163 | 2004 |
| Structural basis of ligand recognition by PABC, a highly specific peptide‐binding domain found in poly (A)‐binding protein and a HECT ubiquitin ligase G Kozlov, G De Crescenzo, NS Lim, N Siddiqui, D Fantus, A Kahvejian, ... The EMBO journal 23 (2), 272-281, 2004 | 144 | 2004 |
| Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain*♦ G Kozlov, S Bastos-Aristizabal, P Määttänen, A Rosenauer, F Zheng, ... Journal of Biological Chemistry 285 (46), 35551-35557, 2010 | 133 | 2010 |
| SMPD1 mutations, activity, and α‐synuclein accumulation in Parkinson's disease RN Alcalay, V Mallett, B Vanderperre, O Tavassoly, Y Dauvilliers, RYJ Wu, ... Movement Disorders 34 (4), 526-535, 2019 | 129 | 2019 |
| Reading the ubiquitin postal code JF Trempe Current opinion in structural biology 21 (6), 792-801, 2011 | 125 | 2011 |
| Mechanisms of PINK1, ubiquitin and Parkin interactions in mitochondrial quality control and beyond AN Bayne, JF Trempe Cellular and Molecular Life Sciences 76 (23), 4589-4611, 2019 | 116 | 2019 |
| Mechanism of Lys48‐linked polyubiquitin chain recognition by the Mud1 UBA domain JF Trempe, NR Brown, ED Lowe, C Gordon, ID Campbell, MEM Noble, ... The EMBO journal 24 (18), 3178-3189, 2005 | 116 | 2005 |
| Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies L Krohn, TN Öztürk, B Vanderperre, B Ouled Amar Bencheikh, JA Ruskey, ... Annals of neurology 87 (1), 139-153, 2020 | 109 | 2020 |
| Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation MY Tang, M Vranas, AI Krahn, S Pundlik, JF Trempe, EA Fon Nature communications 8 (1), 14697, 2017 | 107 | 2017 |
Kalle GehringMcGill UniversityVerified email at mcgill.ca
