| The angiotensin receptor blocker losartan suppresses growth of pulmonary metastases via AT1R-independent inhibition of CCR2 signaling and monocyte recruitment DP Regan, JW Coy, KK Chahal, L Chow, JN Kurihara, AM Guth, ... The Journal of Immunology 202 (10), 3087-3102, 2019 | 81 | 2019 |
| Hedgehog pathway and smoothened inhibitors in cancer therapies KK Chahal, M Parle, R Abagyan Anti-cancer drugs 29 (5), 387-401, 2018 | 46 | 2018 |
| Design and characterization of an intracellular covalent ligand for CC chemokine receptor 2 NV Ortiz Zacarías, KK Chahal, T Šimková, C Van Der Horst, Y Zheng, ... Journal of Medicinal Chemistry 64 (5), 2608-2621, 2021 | 31 | 2021 |
| Establishing bioequivalence of racemic venlafaxine formulations using stereoselective assay method: Is it necessary? K Kandhwal, S Dey, S Nazarudheen, S Reyar, S Mishra, NR Thudi, ... Chirality 23 (10), 948-954, 2011 | 16 | 2011 |
| Pharmacokinetics of a fixed-dose combination of atorvastatin and metformin extended release versus concurrent administration of individual formulations: a randomized, open … K Kandhwal, S Dey, S Nazarudheen, R Arora, S Reyar, NR Thudi, T Monif, ... Clinical drug investigation 31 (12), 853-863, 2011 | 15 | 2011 |
| Orphan receptor GPR37L1 remains unliganded T Ngo, BP Wilkins, SS So, P Keov, KK Chahal, AM Finch, JLJ Coleman, ... Nature chemical biology 17 (4), 383-386, 2021 | 13 | 2021 |
| Identification of Four Amoebicidal Nontoxic Compounds by a Molecular Docking Screen of Naegleria fowleri Sterol Δ8−Δ7-Isomerase and Phenotypic Assays D Shi, KK Chahal, P Oto, LF Nothias, A Debnath, JH McKerrow, ... ACS infectious diseases 5 (12), 2029-2038, 2019 | 13 | 2019 |
| Combining benefits of an adrenergic and a muscarinic blocker in a single formulation–A pharmacokinetic evaluation S Nazarudheen, S Dey, K Kandhwal, R Arora, S Reyar, AH Khuroo, ... Regulatory toxicology and pharmacology 67 (2), 226-231, 2013 | 13 | 2013 |
| Dexamethasone and fludrocortisone inhibit hedgehog signaling in embryonic cells KK Chahal, M Parle, R Abagyan ACS omega 3 (9), 12019-12025, 2018 | 10 | 2018 |
| Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma AR Chahal KK, Li J, Kufareva I, Parle M, Durden DL, Wechsler-Reya RJ, Chen CC PLOS ONE 14 (9), e0214901, 2019 | 7 | 2019 |
| Essential strategies for the detection of constitutive and ligand-dependent Gi-directed activity of 7TM receptors using bioluminescence resonance energy transfer S Endzhievskaya, K Chahal, J Resnick, E Khare, S Roy, TM Handel, ... bioRxiv, 2024 | 1 | 2024 |
| Regulatory recommendations for clopidogrel: Focus on validation of a reliable bioanalytical method and its application to a bioequivalence study S Dey, K Kandhwal, S Nazarudheen, O Singh, SK Mukherjee, S Mishra, ... Clinical Research and Regulatory Affairs 28 (4), 87-95, 2011 | 1 | 2011 |
| Misgivings and mispairings in orphan G protein-coupled receptor research: GPR37L1, GPR146 and GPR161 should still be considered orphan receptors BP Wilkins, K Patel, SS So, A Finch, K Chahal, T Ngo, I Kufareva, ... BRITISH JOURNAL OF PHARMACOLOGY 180, 659-660, 2023 | | 2023 |
| Orphan G protein-coupled receptor, GPR37L1: pharmacological toolbox empty once again T Ngo, BP Wilkins, SS So, P Keov, KK Chahal, AM Finch, JLJ Coleman, ... bioRxiv, 2020.09. 11.290486, 2020 | | 2020 |
| Dynamic Structural Modeling Revealed That Nilotinib Inhibits Smoothened Signaling KK Chahal, J Li, I Kufareva, D Durden, RW Reya, R Abagyan, CC Chen Neurosurgery 66 (Supplement_1), 310-806, 2019 | | 2019 |
| Multi-target pharmacology of kinase inhibitors, beneficial off-targets and allosteric sites R Abagyan, I Kufareva, K Chahal, D Shi ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
| Orthosteric and allosteric antagonism of chemokine receptors: Structural insights into compound affinity and selectivity K Chahal, G Baker, Y Zheng, A Tebben, T Handel, I Kufareva ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
| Diphenolic Acid in Plastics Activates Smoothened Receptor K Kandhwal, I Kufareva, M Parle, R Abagyan The FASEB Journal 30, 697.3-697.3, 2016 | | 2016 |
| Computationally guided repurposing of approved, multi-targeted therapeutics for smoothened-dependent cancers K Kandhwal, M Parle, R Abagyan, I Kufareva ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
| The road to Insurmountability: Novel avenues to better target CC Chemokine NV Ortiz Zacarías receptor 540, 462-465, 2016 | | 2016 |
Irina KufarevaProfessor, UCSDVerified email at ucsd.edu
