| Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations BS Selinsky, K Gupta, CT Sharkey, PJ Loll Biochemistry 40 (17), 5172-5180, 2001 | 367 | 2001 |
| CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere SJ Falk, LY Guo, N Sekulic, EM Smoak, T Mani, GA Logsdon, K Gupta, ... Science 348 (6235), 699-703, 2015 | 267 | 2015 |
| The concentration-dependent membrane activity of cecropin A L Silvestro, K Gupta, JN Weiser, PH Axelsen Biochemistry 36 (38), 11452-11460, 1997 | 177 | 1997 |
| The 2.0 Å resolution crystal structure of prostaglandin H2 synthase-1: structural insights into an unusual peroxidase K Gupta, BS Selinsky, CJ Kaub, AK Katz, PJ Loll Journal of molecular biology 335 (2), 503-518, 2004 | 148 | 2004 |
| The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation EA Sweeny, ME Jackrel, MS Go, MA Sochor, BM Razzo, ME DeSantis, ... Molecular cell 57 (5), 836-849, 2015 | 113 | 2015 |
| Requirements for catalysis in the Cre recombinase active site B Gibb, K Gupta, K Ghosh, R Sharp, J Chen, GD Van Duyne Nucleic acids research 38 (17), 5817-5832, 2010 | 107 | 2010 |
| Allosteric inhibition of human immunodeficiency virus integrase: late block during viral replication and abnormal multimerization involving specific protein domains K Gupta, T Brady, BM Dyer, N Malani, Y Hwang, F Male, RT Nolte, ... Journal of Biological Chemistry 289 (30), 20477-20488, 2014 | 96 | 2014 |
| Neutron scattering in the biological sciences: progress and prospects R Ashkar, H Bilheux, H Bordallo, R Briber, DJE Callaway, X Cheng, ... Biological Crystallography 74 (12), 1129-1168, 2018 | 91 | 2018 |
| The survival motor neuron protein forms soluble glycine zipper oligomers R Martin, K Gupta, NS Ninan, K Perry, GD Van Duyne Structure 20 (11), 1929-1939, 2012 | 91 | 2012 |
| Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1α/ERRγ complex S Devarakonda, K Gupta, MJ Chalmers, JF Hunt, PR Griffin, ... Proceedings of the National Academy of Sciences 108 (46), 18678-18683, 2011 | 85 | 2011 |
| Structural basis for inhibitor-induced aggregation of HIV integrase K Gupta, V Turkki, S Sherrill-Mix, Y Hwang, G Eilers, L Taylor, C McDanal, ... PLoS biology 14 (12), e1002584, 2016 | 82 | 2016 |
| Tetrameric structure of a serine integrase catalytic domain P Yuan, K Gupta, GD Van Duyne Structure 16 (8), 1275-1286, 2008 | 73 | 2008 |
| p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation Z Tao, A Fusco, DB Huang, K Gupta, D Young Kim, CF Ware, ... Proceedings of the National Academy of Sciences 111 (45), 15946-15951, 2014 | 72 | 2014 |
| Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2) R Larue, K Gupta, C Wuensch, N Shkriabai, JJ Kessl, E Danhart, L Feng, ... Journal of Biological Chemistry 287 (41), 34044-34058, 2012 | 72 | 2012 |
| First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer EC Arturo, K Gupta, A Héroux, L Stith, PJ Cross, EJ Parker, PJ Loll, ... Proceedings of the National Academy of Sciences 113 (9), 2394-2399, 2016 | 70 | 2016 |
| Functional activity of the H3. 3 histone chaperone complex HIRA requires trimerization of the HIRA subunit D Ray-Gallet, MD Ricketts, Y Sato, K Gupta, E Boyarchuk, T Senda, ... Nature communications 9 (1), 3103, 2018 | 68 | 2018 |
| Tankyrase-1 ankyrin repeats form an adaptable binding platform for targets of ADP-ribose modification T Eisemann, M McCauley, MF Langelier, K Gupta, S Roy, GD Van Duyne, ... Structure 24 (10), 1679-1692, 2016 | 66 | 2016 |
| Preferential synapsis of loxP sites drives ordered strand exchange in Cre-loxP site-specific recombination K Ghosh, CK Lau, K Gupta, GD Van Duyne Nature chemical biology 1 (5), 275-282, 2005 | 61 | 2005 |
| Recognition of the TDP-43 nuclear localization signal by importin α1/β SG Doll, H Meshkin, AJ Bryer, F Li, YH Ko, RK Lokareddy, RE Gillilan, ... Cell reports 39 (13), 2022 | 57 | 2022 |
| Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation ME DeSantis, EA Sweeny, D Snead, EH Leung, MS Go, K Gupta, ... Journal of Biological Chemistry 289 (2), 848-867, 2014 | 57 | 2014 |
Frederic BushmanVerified email at mail.med.upenn.edu
