| Design, implementation, and in vivo validation of a novel proton FLASH radiation therapy system ES Diffenderfer, II Verginadis, MM Kim, K Shoniyozov, A Velalopoulou, ... International Journal of Radiation Oncology* Biology* Physics 106 (2), 440-448, 2020 | 558 | 2020 |
| FLASH proton radiotherapy spares normal epithelial and mesenchymal tissues while preserving sarcoma response A Velalopoulou, IV Karagounis, GM Cramer, MM Kim, G Skoufos, D Goia, ... Cancer research 81 (18), 4808-4821, 2021 | 201 | 2021 |
| A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression II Verginadis, H Avgousti, J Monslow, G Skoufos, F Chinga, K Kim, ... Nature cell biology 24 (6), 940-953, 2022 | 162 | 2022 |
| Single-cell analysis reveals effective siRNA delivery in brain tumors with microbubble-enhanced ultrasound and cationic nanoparticles Y Guo, H Lee, Z Fang, A Velalopoulou, J Kim, MB Thomas, J Liu, ... Science advances 7 (18), eabf7390, 2021 | 103 | 2021 |
| Effects of catechin and epicatechin on superoxide dismutase and glutathione peroxidase activity, in vivo YV Simos, II Verginadis, IK Toliopoulos, AP Velalopoulou, IV Karagounis, ... Redox report 17 (5), 181-186, 2012 | 84 | 2012 |
| Ultrafast tracking of oxygen dynamics during proton FLASH M El Khatib, AL Van Slyke, A Velalopoulou, MM Kim, K Shoniyozov, ... International Journal of Radiation Oncology* Biology* Physics 113 (3), 624-634, 2022 | 77 | 2022 |
| Key biological mechanisms involved in high-LET radiation therapies with a focus on DNA damage and repair Z Nikitaki, A Velalopoulou, V Zanni, I Tremi, S Havaki, M Kokkoris, ... Expert Reviews in Molecular Medicine 24, e15, 2022 | 77 | 2022 |
| A novel mouse model of radiation-induced cardiac injury reveals biological and radiological biomarkers of cardiac dysfunction with potential clinical relevance AD Dreyfuss, D Goia, K Shoniyozov, SV Shewale, A Velalopoulou, ... Clinical Cancer Research 27 (8), 2266-2276, 2021 | 64 | 2021 |
| Asbestos induces oxidative stress and activation of Nrf2 signaling in murine macrophages: chemopreventive role of the synthetic lignan secoisolariciresinol diglucoside (LGM2605) RA Pietrofesa, A Velalopoulou, SM Albelda, M Christofidou-Solomidou International journal of molecular sciences 17 (3), 322, 2016 | 64 | 2016 |
| Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice RA Pietrofesa, A Velalopoulou, E Arguiri, CW Menges, JR Testa, ... Carcinogenesis 37 (2), 177-187, 2016 | 60 | 2016 |
| A facile approach to hydrophilic oxidized fullerenes and their derivatives as cytotoxic agents and supports for nanobiocatalytic systems P Zygouri, K Spyrou, E Mitsari, M Barrio, R Macovez, M Patila, H Stamatis, ... Scientific reports 10 (1), 8244, 2020 | 58 | 2020 |
| The flaxseed-derived lignan phenolic secoisolariciresinol diglucoside (SDG) protects non-malignant lung cells from radiation damage A Velalopoulou, S Tyagi, RA Pietrofesa, E Arguiri, ... International journal of molecular sciences 17 (1), 7, 2015 | 50 | 2015 |
| Oxygen monitoring in model solutions and in vivo in mice during proton irradiation at conventional and FLASH dose rates AL Van Slyke, M El Khatib, A Velalopoulou, E Diffenderfer, K Shoniyozov, ... Radiation research 198 (2), 181-189, 2022 | 47 | 2022 |
| Closed-loop trans-skull ultrasound hyperthermia leads to improved drug delivery from thermosensitive drugs and promotes changes in vascular transport dynamics in brain tumors C Kim, Y Guo, A Velalopoulou, J Leisen, A Motamarry, K Ramajayam, ... Theranostics 11 (15), 7276, 2021 | 45 | 2021 |
| Towards novel multifunctional pillared nanostructures: Effective intercalation of adamantylamine in graphene oxide and smectite clays K Spyrou, G Potsi, EK Diamanti, X Ke, E Serestatidou, II Verginadis, ... Advanced Functional Materials 24 (37), 5841-5850, 2014 | 43 | 2014 |
| Beneficial effects of electromagnetic radiation in cancer I Verginadis, A Evangelou, A Velalopoulou, D Peschos, I Karagounis, ... INTECH Open Access Publisher, 2012 | 22 | 2012 |
| Preclinical models of radiation-induced cardiac toxicity: Potential mechanisms and biomarkers AD Dreyfuss, A Velalopoulou, H Avgousti, BI Bell, II Verginadis Frontiers in oncology 12, 920867, 2022 | 21 | 2022 |
| Synthetic secoisolariciresinol diglucoside (LGM2605) protects human lung in an ex vivo model of proton radiation damage A Velalopoulou, S Chatterjee, RA Pietrofesa, C Koziol-White, ... International journal of molecular sciences 18 (12), 2525, 2017 | 20 | 2017 |
| Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer P Chowdhury, A Velalopoulou, II Verginadis, G Morcos, PE Loo, MM Kim, ... Molecular Cancer Therapeutics 23 (6), 877-889, 2024 | 17 | 2024 |
| Analgesic effect of the electromagnetic resonant frequencies derived from the NMR spectrum of morphine II Verginadis, YV Simos, AP Velalopoulou, AN Vadalouca, VP Kalfakakou, ... Electromagnetic biology and medicine 31 (4), 275-284, 2012 | 15 | 2012 |
Ioannis (Yiannis) VerginadisResearch Assistant Professor, Department of Radiation Oncology, Perelman School of Medicine, UPennVerified email at pennmedicine.upenn.edu
