| Design, implementation, and in vivo validation of a novel proton FLASH radiation therapy system ES Diffenderfer, II Verginadis, MM Kim, K Shoniyozov, A Velalopoulou, ... International Journal of Radiation Oncology* Biology* Physics 106 (2), 440-448, 2020 | 558 | 2020 |
| Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response M Uribe-Herranz, S Rafail, S Beghi, L Gil-de-Gómez, I Verginadis, ... The Journal of clinical investigation 130 (1), 466-479, 2020 | 322 | 2020 |
| ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis S Dey, CM Sayers, II Verginadis, SL Lehman, Y Cheng, GJ Cerniglia, ... The Journal of clinical investigation 125 (7), 2592-2608, 2015 | 312 | 2015 |
| ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression F Tameire, II Verginadis, NM Leli, C Polte, CS Conn, R Ojha, ... Nature cell biology 21 (7), 889-899, 2019 | 270 | 2019 |
| FLASH proton radiotherapy spares normal epithelial and mesenchymal tissues while preserving sarcoma response A Velalopoulou, IV Karagounis, GM Cramer, MM Kim, G Skoufos, D Goia, ... Cancer research 81 (18), 4808-4821, 2021 | 201 | 2021 |
| A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression II Verginadis, H Avgousti, J Monslow, G Skoufos, F Chinga, K Kim, ... Nature cell biology 24 (6), 940-953, 2022 | 162 | 2022 |
| A simple procedure for estimation of total body surface area and determination of a new value of Meeh's constant in rats E Gouma, Y Simos, I Verginadis, E Lykoudis, A Evangelou, ... Laboratory animals 46 (1), 40-45, 2012 | 158 | 2012 |
| Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapy F Tameire, II Verginadis, C Koumenis Seminars in cancer biology 33, 3-15, 2015 | 145 | 2015 |
| Comparison of FLASH proton entrance and the spread-out Bragg peak dose regions in the sparing of mouse intestinal crypts and in a pancreatic tumor model MM Kim, II Verginadis, D Goia, A Haertter, K Shoniyozov, W Zou, A Maity, ... Cancers 13 (16), 4244, 2021 | 117 | 2021 |
| Antioxidant and anti-platelet properties of milk from goat, donkey and cow: An in vitro, ex vivo and in vivo study Y Simos, A Metsios, I Verginadis, AG D’Alessandro, P Loiudice, E Jirillo, ... International Dairy Journal 21 (11), 901-906, 2011 | 108 | 2011 |
| Synthesis, structural characterization and biological studies of the triphenyltin (IV) complex with 2-thiobarbituric acid VI Balas, II Verginadis, GD Geromichalos, N Kourkoumelis, L Male, ... European journal of medicinal chemistry 46 (7), 2835-2844, 2011 | 107 | 2011 |
| Synthesis, structural characterization and biological studies of novel mixed ligand Ag (I) complexes with triphenylphosphine and aspirin or salicylic acid M Poyraz, CN Banti, N Kourkoumelis, V Dokorou, MJ Manos, M Simčič, ... Inorganica Chimica Acta 375 (1), 114-121, 2011 | 89 | 2011 |
| ER translocation of the MAPK pathway drives therapy resistance in BRAF-mutant melanoma R Ojha, NM Leli, A Onorati, S Piao, II Verginadis, F Tameire, VW Rebecca, ... Cancer discovery 9 (3), 396-415, 2019 | 87 | 2019 |
| Effects of catechin and epicatechin on superoxide dismutase and glutathione peroxidase activity, in vivo YV Simos, II Verginadis, IK Toliopoulos, AP Velalopoulou, IV Karagounis, ... Redox report 17 (5), 181-186, 2012 | 84 | 2012 |
| Oxidative stress in patients treated with continuous ambulatory peritoneal dialysis (CAPD) and the significant role of vitamin C and E supplementation G Boudouris, II Verginadis, YV Simos, A Zouridakis, V Ragos, ... International urology and nephrology 45 (4), 1137-1144, 2013 | 73 | 2013 |
| Clinical measures, radiomics, and genomics offer synergistic value in AI-based prediction of overall survival in patients with glioblastoma A Fathi Kazerooni, S Saxena, E Toorens, D Tu, V Bashyam, H Akbari, ... Scientific Reports 12 (1), 8784, 2022 | 72 | 2022 |
| Radiosensitization by the PARP inhibitor olaparib in BRCA1-proficient and deficient high-grade serous ovarian carcinomas Y Bi, II Verginadis, S Dey, L Lin, L Guo, Y Zheng, C Koumenis Gynecologic oncology 150 (3), 534-544, 2018 | 66 | 2018 |
| Structural Properties, Cytotoxicity, and Anti‐Inflammatory Activity of Silver (I) Complexes with tris (p‐tolyl) Phosphine and 5‐Chloro‐2‐Mercaptobenzothiazole L Kyros, N Kourkoumelis, M Kubicki, L Male, MB Hursthouse, II Verginadis, ... Bioinorganic Chemistry and Applications 2010 (1), 386860, 2010 | 66 | 2010 |
| A novel mouse model of radiation-induced cardiac injury reveals biological and radiological biomarkers of cardiac dysfunction with potential clinical relevance AD Dreyfuss, D Goia, K Shoniyozov, SV Shewale, A Velalopoulou, ... Clinical Cancer Research 27 (8), 2266-2276, 2021 | 64 | 2021 |
| Radiotherapy toxicities: mechanisms, management, and future directions II Verginadis, DE Citrin, B Ky, SJ Feigenberg, AG Georgakilas, ... The Lancet 405 (10475), 338-352, 2025 | 62 | 2025 |
Constantinos KoumenisDepartment of Radiation Oncology, University of Pennsylvania School of MedicineVerified email at upenn.edu
