| Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions DG Lupiáñez, K Kraft, V Heinrich, P Krawitz, F Brancati, E Klopocki, ... Cell 161 (5), 1012-1025, 2015 | 2493 | 2015 |
| Enhancer redundancy provides phenotypic robustness in mammalian development M Osterwalder, I Barozzi, V Tissières, Y Fukuda-Yuzawa, BJ Mannion, ... Nature 554 (7691), 239-243, 2018 | 727 | 2018 |
| Progressive loss of function in a limb enhancer during snake evolution EZ Kvon, OK Kamneva, US Melo, I Barozzi, M Osterwalder, BJ Mannion, ... Cell 167 (3), 633-642. e11, 2016 | 409 | 2016 |
| Ultraconserved enhancers are required for normal development DE Dickel, AR Ypsilanti, R Pla, Y Zhu, I Barozzi, BJ Mannion, YS Khin, ... Cell 172 (3), 491-499. e15, 2018 | 224 | 2018 |
| Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development A Galli, D Robay, M Osterwalder, X Bao, JD Benazet, M Tariq, R Paro, ... PLoS genetics 6 (4), e1000901, 2010 | 188 | 2010 |
| Loss of extreme long-range enhancers in human neural crest drives a craniofacial disorder HK Long, M Osterwalder, IC Welsh, K Hansen, JOJ Davies, YE Liu, ... Cell Stem Cell 27 (5), 765-783. e14, 2020 | 179 | 2020 |
| HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme M Osterwalder, D Speziale, M Shoukry, R Mohan, R Ivanek, M Kohler, ... Developmental cell 31 (3), 345-357, 2014 | 143 | 2014 |
| Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog) AJ Will, G Cova, M Osterwalder, WL Chan, L Wittler, N Brieske, V Heinrich, ... Nature genetics 49 (10), 1539-1545, 2017 | 142 | 2017 |
| GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis J Lopez-Rios, D Speziale, D Robay, M Scotti, M Osterwalder, ... Developmental cell 22 (4), 837-848, 2012 | 124 | 2012 |
| Genome-wide compendium and functional assessment of in vivo heart enhancers DE Dickel, I Barozzi, Y Zhu, Y Fukuda-Yuzawa, M Osterwalder, ... Nature communications 7 (1), 12923, 2016 | 121 | 2016 |
| Cardiac reprogramming factors synergistically activate genome-wide cardiogenic stage-specific enhancers H Hashimoto, Z Wang, GA Garry, VS Malladi, GA Botten, W Ye, H Zhou, ... Cell stem cell 25 (1), 69-86. e5, 2019 | 120 | 2019 |
| Dual RMCE for efficient re-engineering of mouse mutant alleles M Osterwalder, A Galli, B Rosen, WC Skarnes, R Zeller, J Lopez-Rios Nature methods 7 (11), 893-895, 2010 | 91 | 2010 |
| Distal limb patterning requires modulation of cis-regulatory activities by HOX13 R Sheth, I Barozzi, D Langlais, M Osterwalder, S Nemec, HL Carlson, ... Cell reports 17 (11), 2913-2926, 2016 | 86 | 2016 |
| Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium NJ VanDusen, J Casanovas, JW Vincentz, BA Firulli, M Osterwalder, ... Cell reports 9 (6), 2071-2083, 2014 | 85 | 2014 |
| HAND2 target gene regulatory networks control atrioventricular canal and cardiac valve development F Laurent, A Girdziusaite, J Gamart, I Barozzi, M Osterwalder, JA Akiyama, ... Cell reports 19 (8), 1602-1613, 2017 | 79 | 2017 |
| The mole genome reveals regulatory rearrangements associated with adaptive intersexuality F M. Real, SA Haas, P Franchini, P Xiong, O Simakov, H Kuhl, R Schöpflin, ... Science 370 (6513), 208-214, 2020 | 78 | 2020 |
| Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos J Itou, H Kawakami, T Quach, M Osterwalder, SM Evans, R Zeller, ... Development 139 (9), 1620-1629, 2012 | 67 | 2012 |
| Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors S Kult, T Olender, M Osterwalder, S Markman, D Leshkowitz, S Krief, ... Elife 10, e55361, 2021 | 52 | 2021 |
| Noncoding deletions reveal a gene that is critical for intestinal function D Oz-Levi, T Olender, I Bar-Joseph, Y Zhu, D Marek-Yagel, I Barozzi, ... Nature 571 (7763), 107-111, 2019 | 45 | 2019 |
| Characterization of mammalian in vivo enhancers using mouse transgenesis and CRISPR genome editing M Osterwalder, S Tran, RD Hunter, EM Meky, K von Maydell, ... Craniofacial Development: Methods and Protocols, 147-186, 2021 | 37 | 2021 |
Axel ViselLawrence Berkeley National LaboratoryVerified email at lbl.gov
