| Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions DG Lupiáñez, K Kraft, V Heinrich, P Krawitz, F Brancati, E Klopocki, ... Cell 161 (5), 1012-1025, 2015 | 2494 | 2015 |
| Formation of new chromatin domains determines pathogenicity of genomic duplications M Franke, DM Ibrahim, G Andrey, W Schwarzer, V Heinrich, R Schöpflin, ... Nature 538 (7624), 265-269, 2016 | 788 | 2016 |
| Functional dissection of the Sox9–Kcnj2 locus identifies nonessential and instructive roles of TAD architecture A Despang, R Schöpflin, M Franke, S Ali, I Jerković, C Paliou, WL Chan, ... Nature genetics 51 (8), 1263-1271, 2019 | 351 | 2019 |
| Deletions, inversions, duplications: engineering of structural variants using CRISPR/Cas in mice K Kraft, S Geuer, AJ Will, WL Chan, C Paliou, M Borschiwer, I Harabula, ... Cell reports 10 (5), 833-839, 2015 | 270 | 2015 |
| Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis BK Kragesteen, M Spielmann, C Paliou, V Heinrich, R Schöpflin, ... Nature genetics 50 (10), 1463-1473, 2018 | 215 | 2018 |
| Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus M Spielmann, F Brancati, PM Krawitz, PN Robinson, DM Ibrahim, ... The American Journal of Human Genetics 91 (4), 629-635, 2012 | 143 | 2012 |
| CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression M Franke, E De la Calle-Mustienes, A Neto, M Almuedo-Castillo, ... Nature communications 12 (1), 5415, 2021 | 78 | 2021 |
| Transduction of peptides and proteins into live cells by cell penetrating peptides F Mussbach, M Franke, A Zoch, B Schaefer, S Reissmann Journal of cellular biochemistry 112 (12), 3824-3833, 2011 | 62 | 2011 |
| Duplications disrupt chromatin architecture and rewire GPR101-enhancer communication in X-linked acrogigantism M Franke, AF Daly, L Palmeira, A Tirosh, A Stigliano, E Trifan, FR Faucz, ... The American Journal of Human Genetics 109 (4), 553-570, 2022 | 46 | 2022 |
| MiR-21 is required for efficient kidney regeneration in fish B Hoppe, S Pietsch, M Franke, S Engel, M Groth, M Platzer, C Englert BMC developmental biology 15 (1), 43, 2015 | 42 | 2015 |
| Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve split-hand/foot malformation type 3 G Cova, J Glaser, R Schöpflin, CA Prada-Medina, S Ali, M Franke, ... nature communications 14 (1), 1475, 2023 | 29 | 2023 |
| An evolutionary perspective of regulatory landscape dynamics in development and disease M Franke, JL Gómez-Skarmeta Current opinion in cell biology 55, 24-29, 2018 | 20 | 2018 |
| Gain of gene regulatory network interconnectivity at the origin of vertebrates A Gil-Gálvez, S Jiménez-Gancedo, A Pérez-Posada, M Franke, ... Proceedings of the National Academy of Sciences 119 (11), e2114802119, 2022 | 18 | 2022 |
| Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression A Despang, R Schöpflin, M Franke, S Ali, I Jerkovic, C Paliou, WL Chan, ... bioRxiv, 566562, 2019 | 13 | 2019 |
| Regulatory architecture of the RCA gene cluster captures an intragenic TAD boundary, CTCF-mediated chromatin looping and a long-range intergenic enhancer J Cheng, JS Clayton, RD Acemel, Y Zheng, RL Taylor, S Keleş, M Franke, ... Frontiers in Immunology 13, 901747, 2022 | 10 | 2022 |
| Position effects at the FGF8 locus are associated with femoral hypoplasia M Socha, A Sowińska-Seidler, US Melo, BK Kragesteen, M Franke, ... The American Journal of Human Genetics 108 (9), 1725-1734, 2021 | 8 | 2021 |
| Chromatin conformation capture in the clinic: 4C-seq/HiC distinguishes pathogenic from neutral duplications at the GPR101 locus AF Daly, LA Dunnington, DF Rodriguez-Buritica, E Spiegel, F Brancati, ... Genome Medicine 16 (1), 112, 2024 | 7 | 2024 |
| Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes J Glaser, G Cova, B Fauler, CA Prada-Medina, V Stanislas, MHQ Phan, ... Nature Genetics 57 (7), 1766-1776, 2025 | 4 | 2025 |
| Case report: Management of pediatric gigantism caused by the TADopathy, X-linked acrogigantism M Caruso, D Mazzatenta, S Asioli, G Costanza, G Trivellin, M Franke, ... Frontiers in Endocrinology 15, 1345363, 2024 | 4 | 2024 |
| Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes MS Magri, D Voronov, S Foley, PM Martínez-García, M Franke, GA Cary, ... Nature Ecology & Evolution, 1-17, 2026 | 3 | 2026 |
Stefan MundlosInstitut für Medizinische Genetik und Humangenetik, CharitéVerified email at molgen.mpg.de
