| DNA-RNA hybrids at DSBs interfere with repair by homologous recombination P Ortega, JA Mérida-Cerro, AG Rondón, B Gómez-González, A Aguilera Elife 10, e69881, 2021 | 41 | 2021 |
| HMGB2 regulates the differentiation and stemness of exhausted CD8+ T cells during chronic viral infection and cancer EN Neubert, JM DeRogatis, SA Lewis, KM Viramontes, P Ortega, ... Nature Communications 14 (1), 5631, 2023 | 40 | 2023 |
| APOBEC3B drives PKR-mediated translation shutdown and protects stress granules in response to viral infection L Manjunath, S Oh, P Ortega, A Bouin, E Bournique, A Sanchez, ... Nature communications 14 (1), 820, 2023 | 39 | 2023 |
| Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes A Sanchez, P Ortega, R Sakhtemani, L Manjunath, S Oh, E Bournique, ... Nature communications 15 (1), 2370, 2024 | 33 | 2024 |
| Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion P Ortega, B Gómez-González, A Aguilera Nature communications 10 (1), 5178, 2019 | 28 | 2019 |
| A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination S Muñoz-Galván, M García-Rubio, P Ortega, JF Ruiz, S Jimeno, B Pardo, ... PLoS genetics 13 (5), e1006781, 2017 | 25 | 2017 |
| Heterogeneity of DNA damage incidence and repair in different chromatin contexts P Ortega, B Gomez-Gonzalez, A Aguilera DNA repair 107, 103210, 2021 | 18 | 2021 |
| Cooperative role of PACT and ADAR1 in preventing aberrant PKR activation by self-derived double-stranded RNA L Manjunath, G Santiago, P Ortega, A Sanchez, S Oh, A Garcia, J Li, ... Nature Communications 16 (1), 3246, 2025 | 15 | 2025 |
| Modulation of Activity of a Carotenoid Pathway Through the Use of the TeT-on Regulatory System: Application in the Fungus Fusarium fujikuroi J Marente, P Ortega, J Pardo-Medina, J Avalos, MC Limón Plant and Food carotenoids: Methods and protocols, 343-360, 2020 | 12 | 2020 |
| A CDK-regulated chromatin segregase promoting chromosome replication E Chacin, P Bansal, KU Reusswig, LM Diaz-Santin, P Ortega, P Vizjak, ... Nature Communications 12 (1), 5224, 2021 | 10 | 2021 |
| Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells S Jimeno, E Herrera-Moyano, P Ortega, A Aguilera DNA repair 57, 66-75, 2017 | 9 | 2017 |
| ATM and IRAK1 orchestrate two distinct mechanisms of NF-κB activation in response to DNA damage E Bournique, A Sanchez, S Oh, D Ghazarian, AL Mahieu, L Manjunath, ... Nature Structural & Molecular Biology, 1-16, 2025 | 8 | 2025 |
| Mechanism of DNA replication fork breakage and PARP1 hyperactivation during replication catastrophe P Ortega, E Bournique, J Li, A Sanchez, G Santiago, BR Harris, J Striepen, ... Science Advances 11 (16), eadu0437, 2025 | 6 | 2025 |
| Histone deacetylases facilitate the accurate repair of broken forks B Gómez-González, P Ortega, A Aguilera Molecular & Cellular Oncology 7 (2), 1705731, 2020 | 6 | 2020 |
| ATR safeguards replication forks against APOBEC3B-induced toxic PARP1 trapping P Ortega, EB Bournique, J Li, A Sanchez, G Santiago, BR Harris, ... bioRxiv, 2024.11. 14.623607, 2024 | 3 | 2024 |
| Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage P Ortega, D García-Pichardo, M San Martin-Alonso, AG Rondón, ... Microbial Cell 7 (7), 190, 2020 | 3 | 2020 |
| Oligo-seq protocol for mapping DNA motifs targeted by base editors P Ortega, A Sanchez, M Seldin, R Buisson STAR protocols 6 (2), 103758, 2025 | 1 | 2025 |
| The SMC5/SMC6 complex is critical for resolving R-loop-induced transcription–replication conflicts T Wu, Y Li, Y Zhao, E Bournique, P Ortega, M Nie, Y Wang, H Wang, ... Nucleic Acids Research 54 (2), gkaf1537, 2026 | | 2026 |
| Publisher Correction: ATM and IRAK1 orchestrate two distinct mechanisms of NF-κB activation in response to DNA damage E Bournique, A Sanchez, S Oh, D Ghazarian, AL Mahieu, L Manjunath, ... Nature structural & molecular biology 32 (8), 1580, 2025 | | 2025 |
| Targeting Artemis Sensitizes B Cells to Topoisomerase 2 Poisons by Disrupting DNA-PKcs-Dependent Repair N Pannunzio, M Folkerts, C Hom, A Nguyen, K Shen, V Rangel, P Ortega, ... | | 2025 |
Rémi BuissonAssociate Professor, School of Medicine, University of California, IrvineVerified email at uci.edu
