| Effect of membrane lipid composition on the conformational equilibria of the nicotinic acetylcholine receptor JE Baenziger, ML Morris, TE Darsaut, SE Ryan Journal of Biological Chemistry 275 (2), 777-784, 2000 | 193 | 2000 |
| Lipid-protein interactions at the nicotinic acetylcholine receptor: a functional coupling between nicotinic receptors and phosphatidic acid-containing lipid bilayers CJB daCosta, AA Ogrel, EA McCardy, MP Blanton, JE Baenziger Journal of Biological Chemistry 277 (1), 201-208, 2002 | 139 | 2002 |
| Gating of pentameric ligand-gated ion channels: structural insights and ambiguities CJB daCosta, JE Baenziger Structure 21 (8), 1271-1283, 2013 | 138 | 2013 |
| A lipid-dependent uncoupled conformation of the acetylcholine receptor CJB daCosta, JE Baenziger Journal of Biological Chemistry 284 (26), 17819-17825, 2009 | 136 | 2009 |
| Thermal stabilization of a single-chain Fv antibody fragment by introduction of a disulphide bond NM Young, CR MacKenzie, SA Narang, RP Oomen, JE Baenziger FEBS letters 377 (2), 135-139, 1995 | 124 | 1995 |
| A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors CJB daCosta, L Dey, JPD Therien, JE Baenziger Nature chemical biology 9 (11), 701-707, 2013 | 115 | 2013 |
| Fourier transform infrared and hydrogen/deuterium exchange reveal an exchange-resistant core of α-helical peptide hydrogens in the nicotinic acetylcholine receptor JE Baenziger, N Méthot Journal of Biological Chemistry 270 (49), 29129-29137, 1995 | 115 | 1995 |
| Secondary structure analysis of individual transmembrane segments of the nicotinic acetylcholine receptor by circular dichroism and Fourier transform infrared spectroscopy J Corbin, N Méthot, HH Wang, JE Baenziger, MP Blanton Journal of Biological Chemistry 273 (2), 771-777, 1998 | 101 | 1998 |
| 3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels JE Baenziger, PJ Corringer Neuropharmacology 60 (1), 116-125, 2011 | 92 | 2011 |
| Structure of an antifreeze polypeptide and its precursor from the ocean pout, Macrozoarces americanus. XM Li, KY Trinh, CL Hew, B Buettner, J Baenziger, PL Davies Journal of Biological Chemistry 260 (24), 12904-12909, 1985 | 85 | 1985 |
| Ion channels as lipid sensors: from structures to mechanisms MJ Thompson, JE Baenziger Nature Chemical Biology 16 (12), 1331-1342, 2020 | 84 | 2020 |
| Fourier transform infrared difference spectroscopy of the nicotinic acetylcholine receptor: evidence for specific protein structural changes upon desensitization JE Baenziger, KW Miller, KJ Rothschild Biochemistry 32 (20), 5448-5454, 1993 | 78 | 1993 |
| Nicotinic acetylcholine receptor–lipid interactions: mechanistic insight and biological function JE Baenziger, CM Hénault, JPD Therien, J Sun Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (9), 1806-1817, 2015 | 77 | 2015 |
| Anionic lipids allosterically modulate multiple nicotinic acetylcholine receptor conformational equilibria CJB daCosta, SA Medaglia, N Lavigne, S Wang, CL Carswell, ... Journal of Biological Chemistry 284 (49), 33841-33849, 2009 | 76 | 2009 |
| Phosphatidic acid and phosphatidylserine have distinct structural and functional interactions with the nicotinic acetylcholine receptor CJB daCosta, ID Wagg, ME McKay, JE Baenziger Journal of Biological Chemistry 279 (15), 14967-14974, 2004 | 76 | 2004 |
| Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor E Zarkadas, E Pebay-Peyroula, MJ Thompson, G Schoehn, T Uchański, ... Neuron 110 (8), 1358-1370. e5, 2022 | 73 | 2022 |
| A rapid method for assessing lipid: protein and detergent: protein ratios in membrane-protein crystallization CJB daCosta, JE Baenziger Acta Crystallographica Section D: Biological Crystallography 59 (1), 77-83, 2003 | 70 | 2003 |
| A lipid site shapes the agonist response of a pentameric ligand-gated ion channel CM Hénault, C Govaerts, R Spurny, M Brams, A Estrada-Mondragon, ... Nature chemical biology 15 (12), 1156-1164, 2019 | 67 | 2019 |
| Incorporation of the nicotinic acetylcholine receptor into planar multilamellar films: characterization by fluorescence and Fourier transform infrared difference spectroscopy JE Baenziger, KW Miller, KJ Rothschild Biophysical journal 61 (4), 983-992, 1992 | 67 | 1992 |
| Structural effects of neutral and anionic lipids on the nicotinic acetylcholine receptor: an infrared difference spectroscopy study SE Ryan, CN Demers, JP Chew, JE Baenziger Journal of Biological Chemistry 271 (40), 24590-24597, 1996 | 66 | 1996 |
Stephen Ryan MD, PhD, FRCPCAssistant Professor of Radiology, University of OttawaVerified email at toh.on.ca
