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Mackenzie J Thompson
Mackenzie J Thompson
Postdoctoral Researcher, University of Califonia, Berkeley
Verified email at uottawa.ca
Title
Cited by
Cited by
Year
Ion channels as lipid sensors: from structures to mechanisms
MJ Thompson, JE Baenziger
Nature Chemical Biology 16 (12), 1331-1342, 2020
842020
Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor
E Zarkadas, E Pebay-Peyroula, MJ Thompson, G Schoehn, T Uchański, ...
Neuron 110 (8), 1358-1370. e5, 2022
732022
Structural basis for the modulation of pentameric ligand-gated ion channel function by lipids
MJ Thompson, JE Baenziger
Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (9), 183304, 2020
392020
Recent insight into lipid binding and lipid modulation of pentameric ligand-gated ion channels
A Ananchenko, TOK Hussein, D Mody, MJ Thompson, JE Baenziger
Biomolecules 12 (6), 814, 2022
202022
A release of local subunit conformational heterogeneity underlies gating in a muscle nicotinic acetylcholine receptor
MJ Thompson, F Mansoub Bekarkhanechi, A Ananchenko, H Nury, ...
Nature Communications 15 (1), 1803, 2024
132024
The functional role of the αM4 transmembrane helix in the muscle nicotinic acetylcholine receptor probed through mutagenesis and coevolutionary analyses
MJ Thompson, JA Domville, JE Baenziger
Journal of Biological Chemistry 295 (32), 11056-11067, 2020
132020
Asynchronous subunit transitions prime acetylcholine receptor activation
MJ Thompson, CJG Tessier, A Ananchenko, C Hénault, JR Emlaw, ...
Science 391 (6780), eadw1264, 2025
42025
Distinct functional roles for the M4 α-helix from each homologous subunit in the heteropentameric ligand-gated ion channel nAChR
MJ Thompson, JA Domville, CH Edrington, A Venes, PM Giguère, ...
Journal of Biological Chemistry 298 (7), 102104, 2022
42022
Asynchronous subunit transitions precede acetylcholine receptor activation
MJ Thompson, CJG Tessier, A Ananchenko, JR Emlaw, F Dehez, ...
bioRxiv, 2024.12. 02.626350, 2024
12024
BPS2025-Asynchronous subunit transitions precede acetylcholine receptor activation
MJ Thompson, CJG Tessier, A Ananchenko, F Dehez, H Nury, ...
Biophysical Journal 124 (3), 373a-374a, 2025
2025
Mechanisms of Lipid Modulation and Agonist Activation in the Muscle Nicotinic Acetylcholine Receptor
M Thompson
Université d'Ottawa/University of Ottawa, 2024
2024
Origin of acetylcholine antagonism in ELIC, a bacterial pentameric ligand-gated ion channel
M Slobodyanyuk, JA Banda-Vázquez, MJ Thompson, RA Dean, ...
Communications Biology 5 (1), 1264, 2022
2022
Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor
JE Baenziger, E Zarkadas, E Pebay-Peyroula, M Thompson, G Schoehn, ...
Biophysical Journal 121 (3), 381a, 2022
2022
Probing the activation mechanisms of a muscle-type acetylcholine receptor using a combination of structural and functional measurements
MJ Thompson, JE Baenziger
Biophysical Journal 121 (3), 243a, 2022
2022
The Structural Basis for Lipid-Sensing in Pentameric Ligand-Gated Ion Channels
JE Baenziger, MJ Thompson
Biophysical Journal 120 (3), 1a, 2021
2021
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Articles 1–15