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Tomasz Uchański
Tomasz Uchański
Verified email at roche.com
Title
Cited by
Cited by
Year
Single-particle cryo-EM at atomic resolution
T Nakane, A Kotecha, A Sente, G McMullan, S Masiulis, PMGE Brown, ...
Nature 587 (7832), 152-156, 2020
10012020
GABAA receptor signalling mechanisms revealed by structural pharmacology
S Masiulis, R Desai, T Uchański, I Serna Martin, D Laverty, D Karia, ...
Nature 565 (7740), 454-459, 2019
6142019
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer
D Laverty, R Desai, T Uchański, S Masiulis, WJ Stec, T Malinauskas, ...
Nature 565 (7740), 516-520, 2019
3512019
Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM
T Uchański, S Masiulis, B Fischer, V Kalichuk, U López-Sánchez, ...
Nature methods 18 (1), 60-68, 2021
1642021
An improved yeast surface display platform for the screening of nanobody immune libraries
T Uchański, T Zögg, J Yin, D Yuan, A Wohlkönig, B Fischer, ...
Scientific reports 9 (1), 382, 2019
1262019
Nanobodies to study protein conformational states
T Uchański, E Pardon, J Steyaert
Current opinion in structural biology 60, 117-123, 2020
1122020
Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor
E Zarkadas, E Pebay-Peyroula, MJ Thompson, G Schoehn, T Uchański, ...
Neuron 110 (8), 1358-1370. e5, 2022
732022
CXCL10 is an agonist of the CC family chemokine scavenger receptor ACKR2/D6
A Chevigné, B Janji, M Meyrath, N Reynders, G D’uonnolo, T Uchański, ...
Cancers 13 (5), 1054, 2021
542021
Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22
M Meyrath, N Reynders, T Uchański, A Chevigné, M Szpakowska
Journal of Leucocyte Biology 109 (2), 373-376, 2021
332021
A new expression vector facilitating production and functional analysis of scFv antibody fragments selected from Tomlinson I+ J phagemid libraries
K Ossysek, T Uchański, M Kulesza, M Bzowska, T Klaus, K Woś, M Madej, ...
Immunology Letters 167 (2), 95-102, 2015
222015
The extended N-terminal domain confers atypical chemokine receptor properties to CXCR3-B
G D’Uonnolo, N Reynders, M Meyrath, D Abboud, T Uchański, ...
Frontiers in immunology 13, 868579, 2022
212022
Nanoluciferase-based methods to monitor activation, modulation and trafficking of atypical chemokine receptors
R Luís, G D’Uonnolo, CB Palmer, M Meyrath, T Uchański, M Wantz, ...
Methods in Cell Biology 169, 279-294, 2022
212022
Nanoluciferase-based complementation assay for systematic profiling of GPCR–GRK interactions
CB Palmer, G D'Uonnolo, R Luís, M Meyrath, T Uchański, A Chevigné, ...
Methods in Cell Biology 169, 309-321, 2022
142022
An improved yeast surface display platform for the screening of nanobody immune libraries. Sci Rep 9 (1): 382
T Uchanski, T Zogg, J Yin, D Yuan, A Wohlkonig, B Fischer, ...
102019
Rapid discovery and characterization of synthetic neutralizing antibodies against anthrax edema toxin
M Farcasanu, AG Wang, T Uchański, LJ Bailey, J Yue, Z Chen, X Wu, ...
Biochemistry 58 (27), 2996-3004, 2019
62019
Allosteric nanobodies to study the interactions between SOS1 and RAS
B Fischer, T Uchański, A Sheryazdanova, S Gonzalez, AN Volkov, ...
Nature Communications 15 (1), 6214, 2024
52024
Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM
C Li, K Willegems, T Uchański, E Pardon, J Steyaert, RG Efremov
Journal of Biological Chemistry 300 (10), 107734, 2024
32024
ChILL & DisCO to discover competitive, connective and allosteric Nanobodies that modulate the SOS1· RAS protein-protein interactions and tune the nucleotide exchange rate
B Fischer, T Uchanski, A Sheryazdanova, S Gonzalez, A Volkov, ...
bioRxiv 10 (2022.12), 06.519258, 2022
32022
Constructing and purifying megabodies starting from individual nanobody sequences
T Uchański, B Fischer, V Kalichuk, A Wohlkönig, T Zögg, E Pardon, ...
32021
Novel Antigen-Binding Chimeric Proteins and Methods and Uses Thereof
J Steyaert, E Pardon, T Uchanski, W Vranken
US Patent App. 18/516,777, 2024
2024
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Articles 1–20