| Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution GJ Williams, C Zhang, JS Thorson Nature chemical biology 3 (10), 657-662, 2007 | 328 | 2007 |
| Probing the aglycon promiscuity of an engineered glycosyltransferase RW Gantt, RD Goff, GJ Williams, JS Thorson Angewandte Chemie (International ed. in English) 47 (46), 8889, 2008 | 162 | 2008 |
| Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution GJ Williams, S Domann, A Nelson, A Berry Proceedings of the National Academy of Sciences 100 (6), 3143-3148, 2003 | 152 | 2003 |
| Development of transcription factor-based designer macrolide biosensors for metabolic engineering and synthetic biology CM Kasey, M Zerrad, Y Li, TA Cropp, GJ Williams ACS synthetic biology 7 (1), 227-239, 2018 | 129 | 2018 |
| Optimizing glycosyltransferase specificity via “hot spot” saturation mutagenesis presents a catalyst for novobiocin glycorandomization GJ Williams, RD Goff, C Zhang, JS Thorson Chemistry & biology 15 (4), 393-401, 2008 | 120 | 2008 |
| The impact of enzyme engineering upon natural product glycodiversification GJ Williams, RW Gantt, JS Thorson Current opinion in chemical biology 12 (5), 556-564, 2008 | 117 | 2008 |
| Engineering polyketide synthases and nonribosomal peptide synthetases GJ Williams Current opinion in structural biology 23 (4), 603-612, 2013 | 113 | 2013 |
| Directed evolution of enzymes for biocatalysis and the life sciences GJ Williams, AS Nelson, A Berry Cellular and molecular life sciences CMLS 61 (24), 3034-3046, 2004 | 111 | 2004 |
| Transcription factor-based biosensors: a molecular-guided approach for natural product engineering MM Mitchler, JM Garcia, NE Montero, GJ Williams Current opinion in biotechnology 69, 172-181, 2021 | 109 | 2021 |
| An artificial pathway for isoprenoid biosynthesis decoupled from native hemiterpene metabolism S Lund, R Hall, GJ Williams ACS synthetic biology 8 (2), 232-238, 2019 | 107 | 2019 |
| Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases I Koryakina, J McArthur, S Randall, MM Draelos, EM Musiol, ... ACS chemical biology 8 (1), 200-208, 2013 | 100 | 2013 |
| Natural product glycosyltransferases: properties and applications GJ Williams, JS Thorson Advances in Enzymology & Related Areas of Molecular Biology 76, 55, 2009 | 93 | 2009 |
| Inversion of extender unit selectivity in the erythromycin polyketide synthase by acyltransferase domain engineering I Koryakina, C Kasey, JB McArthur, AN Lowell, JA Chemler, S Li, ... ACS chemical biology 12 (1), 114-123, 2017 | 91 | 2017 |
| Creation of a pair of stereochemically complementary biocatalysts GJ Williams, T Woodhall, LM Farnsworth, A Nelson, A Berry Journal of the American Chemical Society 128 (50), 16238-16247, 2006 | 83 | 2006 |
| Recombinant E. coli Prototype Strains for in Vivo Glycorandomization GJ Williams, J Yang, C Zhang, JS Thorson ACS chemical biology 6 (1), 95-100, 2011 | 78 | 2011 |
| Promiscuity of a modular polyketide synthase towards natural and non-natural extender units I Koryakina, JB McArthur, MM Draelos, GJ Williams Organic & biomolecular chemistry 11 (27), 4449-4458, 2013 | 75 | 2013 |
| Mutant malonyl‐CoA synthetases with altered specificity for polyketide synthase extender unit generation I Koryakina, GJ Williams ChemBioChem 12 (15), 2289, 2011 | 72 | 2011 |
| A high-throughput fluorescence-based glycosyltransferase screen and its application in directed evolution GJ Williams, JS Thorson Nature Protocols 3 (3), 357-362, 2008 | 65 | 2008 |
| Polyketide bioderivatization using the promiscuous acyltransferase KirCII EM Musiol-Kroll, F Zubeil, T Schafhauser, T Härtner, A Kulik, J McArthur, ... ACS synthetic biology 6 (3), 421-427, 2017 | 64 | 2017 |
| Reprogramming acyl carrier protein interactions of an Acyl-CoA promiscuous trans-acyltransferase Z Ye, EM Musiol, T Weber, GJ Williams Chemistry & biology 21 (5), 636-646, 2014 | 60 | 2014 |
Jon S. ThorsonProfessor and Associate Dean for Research, University of Kentucky College of PharmacyVerified email at uky.edu
