| Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C H Functionalization AN Lowell, MD DeMars, ST Slocum, F Yu, K Anand, JA Chemler, ... Journal of the American Chemical Society 139 (23), 7913-7920, 2017 | 100 | 2017 |
| Inversion of extender unit selectivity in the erythromycin polyketide synthase by acyltransferase domain engineering I Koryakina, C Kasey, JB McArthur, AN Lowell, JA Chemler, S Li, ... ACS chemical biology 12 (1), 114-123, 2017 | 91 | 2017 |
| Hapalindole/ambiguine biogenesis is mediated by a Cope rearrangement, C–C bond-forming cascade S Li, AN Lowell, F Yu, A Raveh, SA Newmister, N Bair, JM Schaub, ... Journal of the American Chemical Society 137 (49), 15366-15369, 2015 | 80 | 2015 |
| Engineering the substrate specificity of a modular polyketide synthase for installation of consecutive non-natural extender units E Kalkreuter, JM CroweTipton, AN Lowell, DH Sherman, GJ Williams Journal of the American Chemical Society 141 (5), 1961-1969, 2019 | 56 | 2019 |
| A concise synthesis of the naphthalene portion of purpuromycin AN Lowell, MW Fennie, MC Kozlowski The Journal of Organic Chemistry 73 (5), 1911-1918, 2008 | 51 | 2008 |
| Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids S Li, AN Lowell, SA Newmister, F Yu, RM Williams, DH Sherman Nature chemical biology 13 (5), 467-469, 2017 | 43 | 2017 |
| Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis SA Newmister, S Li, M Garcia-Borràs, JN Sanders, S Yang, AN Lowell, ... Nature chemical biology 14 (4), 345-351, 2018 | 42 | 2018 |
| Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase E Kalkreuter, KS Bingham, AM Keeler, AN Lowell, JJ Schmidt, ... Nature communications 12 (1), 2193, 2021 | 40 | 2021 |
| LDL-based nanoparticles for contrast enhanced MRI of atheroplaques in mouse models Y Yamakoshi, H Qiao, AN Lowell, M Woods, B Paulose, Y Nakao, ... Chemical Communications 47 (31), 8835-8837, 2011 | 36 | 2011 |
| Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module MA Skiba, AP Sikkema, NA Moss, AN Lowell, M Su, RM Sturgis, ... ACS chemical biology 13 (6), 1640-1650, 2018 | 32 | 2018 |
| Multicomponent microscale biosynthesis of unnatural cyanobacterial indole alkaloids Y Khatri, RM Hohlman, J Mendoza, S Li, AN Lowell, H Asahara, ... ACS synthetic biology 9 (6), 1349-1360, 2020 | 30 | 2020 |
| Alternative spiroketalization methods toward purpuromycin: a diketone approach to prevent benzofuran formation AN Lowell, MW Fennie, MC Kozlowski The Journal of Organic Chemistry 76 (16), 6488-6502, 2011 | 22 | 2011 |
| Probing selectivity and creating structural diversity through hybrid polyketide synthases AA Koch, JJ Schmidt, AN Lowell, DA Hansen, KM Coburn, JA Chemler, ... Angewandte Chemie 132 (32), 13677-13682, 2020 | 21 | 2020 |
| Functionalized low-density lipoprotein nanoparticles for in vivo enhancement of atherosclerosis on magnetic resonance images AN Lowell, H Qiao, T Liu, T Ishikawa, H Zhang, S Oriana, M Wang, ... Bioconjugate Chemistry 23 (11), 2313-2319, 2012 | 21 | 2012 |
| Syntheses of differentially protected isocoumarins AN Lowell, PD Wall, SP Waters, MC Kozlowski Tetrahedron 66 (30), 5573-5582, 2010 | 21 | 2010 |
| Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida E Breiner-Goldstein, Z Eyal, D Matzov, Y Halfon, G Cimicata, M Baum, ... Nucleic acids research 49 (16), 9560-9573, 2021 | 19 | 2021 |
| Biochemical and structural characterization of MycCI, a versatile P450 biocatalyst from the mycinamicin biosynthetic pathway MD DeMars, F Sheng, SR Park, AN Lowell, LM Podust, DH Sherman ACS chemical biology 11 (9), 2642-2654, 2016 | 19 | 2016 |
| Microscale Adaptation of In Vitro Transcription/Translation for High‐Throughput Screening of Natural Product Extract Libraries AN Lowell, N Santoro, SM Swaney, TJ McQuade, PJ Schultz, MJ Larsen, ... Chemical biology & drug design 86 (6), 1331-1338, 2015 | 16 | 2015 |
| Alternative Spiroketalization Methods toward Purpuromycin: A Hemiketal Conjugate Addition Strategy and Use of an Electron-Rich Isocoumarin Precursor R Bandichhor, AN Lowell, MC Kozlowski The Journal of Organic Chemistry 76 (16), 6475-6487, 2011 | 16 | 2011 |
| Expanding the biosynthetic toolbox: the potential and challenges of in vitro type II polyketide synthase research MAJ Rivers, AN Lowell SynBio 2 (1), 85-111, 2024 | 10 | 2024 |
