| Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia PCY Woo, SKP Lau, C Chu, K Chan, H Tsoi, Y Huang, BHL Wong, ... Journal of virology 79 (2), 884-895, 2005 | 2090 | 2005 |
| Systematic determination of the mitochondrial proportion in human and mice tissues for single-cell RNA-sequencing data quality control D Osorio, JJ Cai Bioinformatics 37 (7), 963-967, 2021 | 239 | 2021 |
| Widespread establishment and regulatory impact of Alu exons in human genes S Shen, L Lin, JJ Cai, P Jiang, EJ Kenkel, MR Stroik, S Sato, BL Davidson, ... Proceedings of the National Academy of Sciences 108 (7), 2837-2842, 2011 | 161 | 2011 |
| Pervasive hitchhiking at coding and regulatory sites in humans JJ Cai, JM Macpherson, G Sella, DA Petrov PLoS genetics 5 (1), e1000336, 2009 | 156 | 2009 |
| Diverse splicing patterns of exonized Alu elements in human tissues L Lin, S Shen, A Tye, JJ Cai, P Jiang, BL Davidson, Y Xing PloS Genetics 4 (10), e1000225, 2008 | 139 | 2008 |
| Relaxed purifying selection and possibly high rate of adaptation in primate lineage-specific genes JJ Cai, DA Petrov Genome biology and evolution 2, 393-409, 2010 | 134 | 2010 |
| Genetic variants contribute to gene expression variability in humans AM Hulse, JJ Cai Genetics 193 (1), 95-108, 2013 | 133 | 2013 |
| High diversity of polyketide synthase genes and the melanin biosynthesis gene cluster in Penicillium marneffei PCY Woo, EWT Tam, KTK Chong, JJ Cai, ETK Tung, AHY Ngan, SKP Lau, ... FEBS Journal 277 (18), 3750-3758, 2010 | 126 | 2010 |
| Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder J Guan, JJ Cai, G Ji, PC Sham Translational psychiatry 9 (1), 152, 2019 | 94 | 2019 |
| Aberrant gene expression in humans. Y Zeng, GW Wang, E Yang, G Ji, BL Candice L., JJ Cai PLoS genetics 11 (1), e1004942, 2015 | 90 | 2015 |
| Long noncoding RNA MALAT1 regulates generation of reactive oxygen species and the insulin responses in male mice J Chen, S Ke, L Zhong, J Wu, A Tseng, B Morpurgo, A Golovko, G Wang, ... Biochemical Pharmacology 152, 94-103, 2018 | 88 | 2018 |
| Accelerated evolutionary rate may be responsible for the emergence of lineage-specific genes in ascomycota JJ Cai, PCY Woo, SKP Lau, DK Smith, K Yuen Journal of molecular evolution 63 (1), 1-11, 2006 | 88 | 2006 |
| Novel partitivirus enhances virulence of and causes aberrant gene expression in Talaromyces marneffei SKP Lau, GCS Lo, FWN Chow, RYY Fan, JJ Cai, KY Yuen, PCY Woo MBio 9 (3), 10.1128/mbio. 00947-18, 2018 | 78 | 2018 |
| The mitochondrial genome of the thermal dimorphic fungus< i> Penicillium marneffei</i> is more closely related to those of molds than yeasts PCY Woo, H Zhen, JJ Cai, J Yu, SKP Lau, J Wang, JLL Teng, SSY Wong, ... FEBS letters 555 (3), 469-477, 2003 | 78 | 2003 |
| scTenifoldKnk: An efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation D Osorio, Y Zhong, G Li, Q Xu, Y Yang, Y Tian, RS Chapkin, JZ Huang, ... Patterns 3 (3), 2022 | 75 | 2022 |
| Broker genes in human disease JJ Cai, E Borenstein, DA Petrov Genome Biology and Evolution 2, 815, 2010 | 75 | 2010 |
| Genomic and experimental evidence for a potential sexual cycle in the pathogenic thermal dimorphic fungus< i> Penicillium marneffei</i> PCY Woo, KTK Chong, H Tse, JJ Cai, CCY Lau, AC Zhou, SKP Lau, ... FEBS letters 580 (14), 3409-3416, 2006 | 75 | 2006 |
| The lncRNA RZE1 Controls Cryptococcal Morphological Transition N Chacko, Y Zhao, E Yang, L Wang, JJ Cai, X Lin PLoS genetics 11 (11), e1005692, 2015 | 74 | 2015 |
| Similarly strong purifying selection acts on human disease genes of all evolutionary ages JJ Cai, E Borenstein, R Chen, DA Petrov Genome biology and evolution 1, 131, 2009 | 68 | 2009 |
| MBEToolbox: a Matlab toolbox for sequence data analysis in molecular biology and evolution JJ Cai, DK Smith, X Xia, K Yuen BMC bioinformatics 6 (1), 64, 2005 | 64 | 2005 |
Daniel OsorioSenior Scientific Consultant, QIAGEN Digital InsightsVerified email at qiagen.com
