| Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution LJ Holt, BB Tuch, J Villén, AD Johnson, SP Gygi, DO Morgan Science 325 (5948), 1682, 2009 | 1120 | 2009 |
| Excessive cell growth causes cytoplasm dilution and contributes to senescence GE Neurohr, RL Terry, J Lengefeld, M Bonney, GP Brittingham, F Moretto, ... cell 176 (5), 1083-1097. e18, 2019 | 604 | 2019 |
| mTORC1 controls phase separation and the biophysical properties of the cytoplasm by tuning crowding M Delarue, GP Brittingham, S Pfeffer, IV Surovtsev, S Pinglay, ... Cell 174 (2), 338-349. e20, 2018 | 505 | 2018 |
| Phase transitions in biogenic amorphous calcium carbonate YUT Gong, CE Killian, IC Olson, NP Appathurai, AL Amasino, MC Martin, ... Proceedings of the National Academy of Sciences 109 (16), 6088-6093, 2012 | 346 | 2012 |
| The genome project-write JD Boeke, G Church, A Hessel, NJ Kelley, A Arkin, Y Cai, R Carlson, ... Science 353 (6295), 126-127, 2016 | 320 | 2016 |
| Positive feedback sharpens the anaphase switch LJ Holt, AN Krutchinsky, DO Morgan Nature 454 (7202), 353-357, 2008 | 256 | 2008 |
| A glucose-starvation response regulates the diffusion of macromolecules RP Joyner, JH Tang, J Helenius, E Dultz, C Brune, LJ Holt, S Huet, ... elife 5, e09376, 2016 | 243 | 2016 |
| The class I bHLH factors E2-2A and E2-2B regulate EMT VR Sobrado, G Moreno-Bueno, E Cubillo, LJ Holt, MA Nieto, F Portillo, ... Journal of cell science 122 (7), 1014-1024, 2009 | 167 | 2009 |
| Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization AT Molines, J Lemière, M Gazzola, IE Steinmark, CH Edrington, CT Hsu, ... Developmental cell 57 (4), 466-479. e6, 2022 | 133 | 2022 |
| Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly S Cuylen-Haering, M Petrovic, A Hernandez-Armendariz, ... Nature 587 (7833), 285-290, 2020 | 112 | 2020 |
| Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis LJ Holt, JE Hutti, LC Cantley, DO Morgan Molecular cell 25 (5), 689-702, 2007 | 101 | 2007 |
| Reciprocal regulation of cellular mechanics and metabolism TMJ Evers, LJ Holt, S Alberti, A Mashaghi Nature metabolism 3 (4), 456-468, 2021 | 90 | 2021 |
| Macromolecular crowding limits growth under pressure B Alric, C Formosa-Dague, E Dague, LJ Holt, M Delarue Nature Physics 18 (4), 411-416, 2022 | 88 | 2022 |
| CDKL family kinases have evolved distinct structural features and ciliary function P Canning, K Park, J Goncalves, C Li, CJ Howard, TD Sharpe, LJ Holt, ... Cell reports 22 (4), 885-894, 2018 | 88 | 2018 |
| Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding D Sang, T Shu, CF Pantoja, AI de Opakua, M Zweckstetter, LJ Holt Molecular cell 82 (19), 3693-3711. e10, 2022 | 87 | 2022 |
| Phase separation in biology and disease; current perspectives and open questions S Boeynaems, S Chong, J Gsponer, L Holt, D Milovanovic, DM Mitrea, ... Journal of molecular biology 435 (5), 167971, 2023 | 84 | 2023 |
| Regulatory modules: Coupling protein stability to phopshoregulation during cell division LJ Holt FEBS letters 586 (17), 2773-2777, 2012 | 84 | 2012 |
| Control of nuclear size by osmotic forces in Schizosaccharomyces pombe J Lemière, P Real-Calderon, LJ Holt, TG Fai, F Chang Elife 11, e76075, 2022 | 75 | 2022 |
| Ancestral resurrection reveals evolutionary mechanisms of kinase plasticity CJ Howard, V Hanson-Smith, KJ Kennedy, CJ Miller, HJ Lou, AD Johnson, ... elife 3, e04126, 2014 | 66 | 2014 |
| The Giardia cell cycle progresses independently of the anaphase-promoting complex S Gourguechon, LJ Holt, WZ Cande Journal of cell science 126 (10), 2246-2255, 2013 | 61 | 2013 |
Gregory BrittinghamNew York UniversityVerified email at nyumc.org
