| Genome-scale CRISPR-Cas9 knockout screening in human cells O Shalem, NE Sanjana, E Hartenian, X Shi, DA Scott, TS Mikkelsen, ... Science 343 (6166), 84-87, 2014 | 6448 | 2014 |
| Improved vectors and genome-wide libraries for CRISPR screening NE Sanjana, O Shalem, F Zhang Nature methods 11 (8), 783-784, 2014 | 5976 | 2014 |
| High-throughput functional genomics using CRISPR–Cas9 O Shalem, NE Sanjana, F Zhang Nature Reviews Genetics 16 (5), 299-311, 2015 | 1576 | 2015 |
| Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ... Nature protocols 12 (4), 828-863, 2017 | 1511 | 2017 |
| Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5′ sites S Schwartz, MR Mumbach, M Jovanovic, T Wang, K Maciag, GG Bushkin, ... Cell reports 8 (1), 284-296, 2014 | 1338 | 2014 |
| Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis S Chen, NE Sanjana, K Zheng, O Shalem, K Lee, X Shi, DA Scott, J Song, ... Cell 160 (6), 1246-1260, 2015 | 1198 | 2015 |
| BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature 527 (7577), 192-197, 2015 | 1061 | 2015 |
| A transcription activator-like effector toolbox for genome engineering NE Sanjana, L Cong, Y Zhou, MM Cunniff, G Feng, F Zhang Nature protocols 7 (1), 171-192, 2012 | 1036 | 2012 |
| Identification of essential genes for cancer immunotherapy SJ Patel, NE Sanjana, RJ Kishton, A Eidizadeh, SK Vodnala, M Cam, ... Nature 548 (7669), 537-542, 2017 | 996 | 2017 |
| CRISPR-Cas component systems, methods and compositions for sequence manipulation F Zhang US Patent 8,795,965, 2014 | 782 | 2014 |
| Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains F Zhang, L Cong, RJ Platt, NE Sanjana, F RAN US Patent 8,993,233, 2015 | 685 | 2015 |
| Identification of required host factors for SARS-CoV-2 infection in human cells Z Daniloski, TX Jordan, HH Wessels, DA Hoagland, S Kasela, M Legut, ... Cell 184 (1), 92-105. e16, 2021 | 643 | 2021 |
| A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks O Parnas, M Jovanovic, TM Eisenhaure, RH Herbst, A Dixit, CJ Ye, ... Cell 162 (3), 675-686, 2015 | 591 | 2015 |
| Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells EP Mimitou, A Cheng, A Montalbano, S Hao, M Stoeckius, M Legut, ... Nature methods 16 (5), 409-412, 2019 | 556 | 2019 |
| Hypoxia as a therapy for mitochondrial disease IH Jain, L Zazzeron, R Goli, K Alexa, S Schatzman-Bone, H Dhillon, ... Science 352 (6281), 54-61, 2016 | 521 | 2016 |
| Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 471 | 2010 |
| Massively parallel Cas13 screens reveal principles for guide RNA design HH Wessels, A Méndez-Mancilla, X Guo, M Legut, Z Daniloski, ... Nature biotechnology 38 (6), 722-727, 2020 | 461 | 2020 |
| Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ... Nature 548 (7667), 343-346, 2017 | 457 | 2017 |
| CRISPR in cancer biology and therapy A Katti, BJ Diaz, CM Caragine, NE Sanjana, LE Dow Nature Reviews Cancer 22 (5), 259-279, 2022 | 453 | 2022 |
| Autism genes converge on asynchronous development of shared neuron classes B Paulsen, S Velasco, AJ Kedaigle, M Pigoni, G Quadrato, AJ Deo, ... Nature 602 (7896), 268-273, 2022 | 410 | 2022 |