| Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2 J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ... New England Journal of Medicine 369 (25), 2391-2405, 2013 | 2371 | 2013 |
| Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated … E Avezov, Z Frenkel, M Ehrlich, A Herscovics, GZ Lederkremer Molecular biology of the cell 19 (1), 216-225, 2008 | 184 | 2008 |
| An optical technique for mapping microviscosity dynamics in cellular organelles JE Chambers, M Kubánková, RG Huber, I López-Duarte, E Avezov, ... Acs Nano 12 (5), 4398-4407, 2018 | 166 | 2018 |
| Intracellular Sources of ROS/H2O2 in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum T Konno, EP Melo, JE Chambers, E Avezov Cells 10 (2), 233, 2021 | 148 | 2021 |
| Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox E Avezov, BCS Cross, GS Kaminski Schierle, M Winters, HP Harding, ... Journal of Cell Biology 201 (2), 337-349, 2013 | 120 | 2013 |
| The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes M Lu, FW van Tartwijk, JQ Lin, W Nijenhuis, P Parutto, M Fantham, ... Science advances 6 (51), eabc7209, 2020 | 119 | 2020 |
| Single particle trajectories reveal active endoplasmic reticulum luminal flow D Holcman, P Parutto, JE Chambers, M Fantham, LJ Young, SJ Marciniak, ... Nature cell biology 20 (10), 1118-1125, 2018 | 118 | 2018 |
| Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm P Gulati, E Avezov, M Ma, R Antrobus, P Lehner, S O’Rahilly, GSH Yeo Bioscience reports 34 (5), e00144, 2014 | 114 | 2014 |
| PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress M Kondratyev, E Avezov, M Shenkman, B Groisman, GZ Lederkremer Experimental cell research 313 (16), 3395-3407, 2007 | 100 | 2007 |
| Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker S Preissler, JE Chambers, A Crespillo-Casado, E Avezov, E Miranda, ... Elife 4, e08961, 2015 | 89 | 2015 |
| Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants S Tsunoda, E Avezov, A Zyryanova, T Konno, L Mendes-Silva, ... Elife 3, e03421, 2014 | 89 | 2014 |
| ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity I Mehmeti, S Lortz, E Avezov, A Jörns, S Lenzen Free Radical Biology and Medicine 112, 121-130, 2017 | 82 | 2017 |
| A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation K Kollmann, W Warsch, C Gonzalez-Arias, FL Nice, E Avezov, J Milburn, ... Leukemia 31 (4), 934-944, 2017 | 79 | 2017 |
| ERO1-independent production of H2O2 within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding T Konno, E Pinho Melo, C Lopes, I Mehmeti, S Lenzen, D Ron, E Avezov Journal of Cell Biology 211 (2), 253-259, 2015 | 77 | 2015 |
| A shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins M Shenkman, B Groisman, E Ron, E Avezov, LM Hendershot, ... Journal of Biological Chemistry 288 (4), 2167-2178, 2013 | 72 | 2013 |
| Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models AS Mukadam, LVC Miller, AE Smith, M Vaysburd, SA Sakya, S Sanford, ... Science 379 (6639), 1336-1341, 2023 | 64 | 2023 |
| TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2 EP Melo, C Lopes, P Gollwitzer, S Lortz, S Lenzen, I Mehmeti, ... BMC biology 15 (1), 24, 2017 | 59 | 2017 |
| Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum E Avezov, T Konno, A Zyryanova, W Chen, R Laine, A Crespillo-Casado, ... BMC biology 13 (1), 2, 2015 | 57 | 2015 |
| ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology M Lu, CN Christensen, JM Weber, T Konno, NF Läubli, KM Scherer, ... Nature Methods 20 (4), 569-579, 2023 | 44 | 2023 |
| Stress-induced protein disaggregation in the endoplasmic reticulum catalysed by BiP EP Melo, T Konno, I Farace, MA Awadelkareem, LR Skov, F Teodoro, ... Nature Communications 13 (1), 2501, 2022 | 41 | 2022 |
Clemens F KaminskiProfessor, Dept of Chemical Engineering and Biotechnology, University of CambridgeVerified email at cam.ac.uk
