| Endoplasmic Reticulum Stress in Malignancy HJ Clarke, JE Chambers, E Liniker, SJ Marciniak Cancer Cell 25 (5), 563-573, 2014 | 530 | 2014 |
| Pharmacological targeting of endoplasmic reticulum stress in disease SJ Marciniak, JE Chambers, D Ron Nature Reviews Drug Discovery, 1-26, 2021 | 488 | 2021 |
| The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ... Nature, 2014 | 428 | 2014 |
| An Optical Technique for Mapping Microviscosity Dynamics in Cellular Organelles. JE Chambers, M Kubankova, RG Huber, I López-Duarte, E Avezov, ... ACS nano, 2018 | 166 | 2018 |
| Intracellular Sources of ROS/H2O2 in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum T Konno, EP Melo, JE Chambers, E Avezov Cells 10 (2), 233, 2021 | 148 | 2021 |
| Macromolecular condensation buffers intracellular water potential JL Watson, E Seinkmane, CT Styles, A Mihut, LK Krüger, KE McNally, ... Nature, 1-11, 2023 | 119 | 2023 |
| Single particle trajectories reveal active endoplasmic reticulum luminal flow D Holcman, P Parutto, JE Chambers, M Fantham, LJ Young, SJ Marciniak, ... Nature Cell Biology, 1, 2018 | 118 | 2018 |
| Substrate specificity of the oxidoreductase ERp57 is determined primarily by its interaction with calnexin and calreticulin CE Jessop, TJ Tavender, RH Watkins, JE Chambers, NJ Bulleid Journal of Biological Chemistry 284 (4), 2194-2202, 2009 | 113 | 2009 |
| PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz A Crespillo-Casado, JE Chambers, PM Fischer, SJ Marciniak, D Ron eLife 6, e26109, 2017 | 112 | 2017 |
| Protein misfolding and ER stress JE Chambers, SJ Marciniak American Journal of Physiology-Cell Physiology, 2014 | 109 | 2014 |
| ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load JE Chambers, K Petrova, G Tomba, M Vendruscolo, D Ron The Journal of Cell Biology 198 (3), 371-385, 2012 | 101 | 2012 |
| Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation JE Chambers, LE Dalton, HJ Clarke, E Malzer, CS Dominicus, V Patel, ... eLife, e04872, 2015 | 95 | 2015 |
| The reduction potential of the active site disulfides of human protein disulfide isomerase limits oxidation of the enzyme by Ero1α JE Chambers, TJ Tavender, OBV Oka, S Warwood, D Knight, NJ Bulleid Journal of Biological Chemistry 285 (38), 29200-29207, 2010 | 93 | 2010 |
| Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker S Preissler, JE Chambers, A Crespillo-Casado, E Avezov, E Miranda, ... eLife, 2015 | 89 | 2015 |
| HaloFlippers: A General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living Cells K Straková, J López-Andarias, N Jiménez-Rojo, JE Chambers, ... ACS Central Science, 2020 | 61 | 2020 |
| Z-α1-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state JE Chambers*, N Zubkov, M Kubánková, J Nixon-Abell, I Mela, S Abreu, ... Science Advances 8 (14), eabm2094, 2022 | 38 | 2022 |
| Pulmonary endoplasmic reticulum stress—scars, smoke, and suffocation JA Dickens, E Malzer, JE Chambers, SJ Marciniak The FEBS journal 286 (2), 322-341, 2019 | 38 | 2019 |
| New Concepts in Alpha-1 Antitrypsin Deficiency Disease Mechanisms SJ Marciniak, A Ordóñez, JA Dickens, JE Chambers, V Patel, ... Annals of the American Thoracic Society 13 (Supplement 4), S289-S296, 2016 | 37 | 2016 |
| The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α1-antitrypsin JA Dickens, A Ordóñez, JE Chambers, AJ Beckett, V Patel, E Malzer, ... The FASEB Journal, fj. 201600430R, 2016 | 33 | 2016 |
| Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport T Konno, P Parutto, CC Crapart, V Davì, DMD Bailey, MA Awadelkareem, ... Cell Reports, 2024 | 29 | 2024 |
Stefan MarciniakProfessor of Respiratory Science, CambridgeVerified email at cam.ac.uk
