ZA99252B - Thioether furan nitrone compounds. - Google Patents

Thioether furan nitrone compounds.

Info

Publication number: ZA99252B
Authority: ZA; South Africa
Prior art keywords: nitrone compounds; furan nitrone; thioether furan; thioether; compounds
Prior art date: 1998-01-16

Application number

ZA9900252A

Other languages

English (en)

Inventor

Judith A Kelleher

Yong-Kang Zhang

Kirk R Maples

Original Assignee

Centaur Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-16

Filing date

1999-01-14

Publication date

1999-07-14

1999-01-14 Application filed by Centaur Pharmaceuticals Inc filed Critical Centaur Pharmaceuticals Inc

1999-07-14 Publication of ZA99252B publication Critical patent/ZA99252B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/64—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Psychology (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA9900252A 1998-01-16 1999-01-14 Thioether furan nitrone compounds. ZA99252B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7162698P	1998-01-16	1998-01-16

Publications (1)

Publication Number	Publication Date
ZA99252B true ZA99252B (en)	1999-07-14

Family

ID=22102531

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9900252A ZA99252B (en)	1998-01-16	1999-01-14	Thioether furan nitrone compounds.

Country Status (10)

Country	Link
US (3)	US5998469A (fr)
EP (1)	EP1047683A1 (fr)
JP (1)	JP2002509143A (fr)
CN (1)	CN1291980A (fr)
AU (1)	AU742768B2 (fr)
CA (1)	CA2318357A1 (fr)
NZ (1)	NZ505757A (fr)
TW (1)	TW446703B (fr)
WO (1)	WO1999036415A1 (fr)
ZA (1)	ZA99252B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69917643T2 (de)	1998-07-17	2004-10-07	Renovis Inc	Alpha-(2-hydroxyphenyl)nitrone, diese enthaltenden pharmazeutische zubereitungen sowie deren verwendung zur behandlung von entzündungen
US6730700B2 (en)	1998-12-02	2004-05-04	Renovis, Inc.	3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same
UA66401C2 (en)	1998-12-02	2004-05-17	Sentor Pharmaceuticals Inc	3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same
US6808902B1 (en)	1999-11-12	2004-10-26	Amgen Inc.	Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
ES2706902T3 (es)	2001-06-26	2019-04-01	Amgen Inc	Anticuerpos para OPGL
PL377091A1 (pl)	2002-09-06	2006-01-23	Amgen, Inc.	Ludzkie monoklonalne przeciwciało przeciw-IL-1R1, o właściwościach terapeutycznych
MY150088A (en) *	2003-05-19	2013-11-29	Irm Llc	Immunosuppressant compounds and compositions
US20050059638A1 (en) *	2003-08-04	2005-03-17	Kelly Michael G.	Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) *	2004-02-13	2005-08-18	Kelly Michael G.	2-Substituted and 4-substituted aryl nitrone compounds
WO2006026713A2 (fr) *	2004-08-31	2006-03-09	Tracie Martyn International, Llc	Compositions topiques contenant de la benfotiamine et de la pyridoxamine
US12403181B2 (en)	2018-08-13	2025-09-02	Iltoo Pharma	Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof
EP4526469A1 (fr)	2022-05-16	2025-03-26	Institut National de la Santé et de la Recherche Médicale	Procédés d'évaluation de l'épuisement de cellules souches hématopoïétiques induites par une inflammation chronique

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3666754A (en) *	1965-11-06	1972-05-30	Dainippon Pharmaceutical Co	2-(5-nitrofuryl) nitrone derivatives
US3988159A (en) *	1967-07-28	1976-10-26	American Can Company	Light-sensitive material containing nitrone for forming heat-fixed images
US3834073A (en) *	1971-05-03	1974-09-10	Scm Corp	Phenyl nitrone derivatives useful as seed protectants
US3849934A (en) *	1971-05-03	1974-11-26	Scm Corp	Alpha-aryl-n-lower alkyl nitrone-containing compositions useful as anti-fungal agents
US3950327A (en) *	1972-09-19	1976-04-13	Ciba-Geigy Corporation	New nitrones, their manufacture and their use for the manufacture of n-substituted araliphatic aldehyde-nitrones
US3903049A (en) *	1974-01-30	1975-09-02	Goodyear Tire & Rubber	Oxidation resistant sulfur curable rubbery polymers
US3917700A (en) *	1974-01-30	1975-11-04	Goodyear Tire & Rubber	Nitrone compounds
GB1565966A (en) *	1976-08-04	1980-04-23	Allen & Hanburys Ltd	Aminoalkyl furan derivatives
GB1588417A (en) *	1977-03-15	1981-04-23	Agfa Gevaert	Photoresist materials
US4153722A (en) *	1977-10-06	1979-05-08	William H. Rorer, Inc.	Method of treatment
GB2137619A (en) *	1983-03-30	1984-10-10	Gerald Scott	Nitrone compounds and stabilised rubber compositions containing them
US5352442A (en) *	1985-07-18	1994-10-04	Proctor Peter H	Topical tempo
US5723502A (en) *	1985-07-18	1998-03-03	Proctor; Peter H.	Topical spin trap composition and method
US4871862A (en) *	1986-08-27	1989-10-03	Fisons Corporation	α-Substituted ketonitrone derivatives
US4803282A (en) *	1986-08-27	1989-02-07	Pennwalt Corporation	Alpha-substituted ketonitrone derivatives
US5591761A (en) *	1993-05-20	1997-01-07	Texas Biotechnology Corporation	Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
EP0327263B1 (fr) *	1988-01-29	1994-09-07	PROCTOR, Peter H.	Stimulation de la croissance des cheveux avec nitroxide et autres radicaux
KR960008230B1 (ko) *	1989-10-17	1996-06-21	윌리엄 쥐.씨먼	중추신경계의 산화적 손상에 관련된 질병들을 억제하기 위한 조성물들
ATE209908T1 (de) *	1991-06-18	2001-12-15	Oklahoma Med Res Found	RADIKALFÄNGER (ßSPIN TRAPSß) ZUR BEHANDLUNG VON MIT OXIDATION VON LIPIDEN UND PROTEINEN VERBUNDENEN ERKRANKUNGEN
US5292746A (en) *	1991-09-12	1994-03-08	Merrell Dow Pharmaceuticals Inc.	Cyclic nitrones, pharmaceutical compositions thereof and their use in treating shock
GB9300894D0 (en) *	1992-02-07	1993-03-10	Zeneca Ltd	Oxime derivatives
US5455272A (en) *	1993-10-22	1995-10-03	Oklahoma Medical Research Foundation	Spin trap nitronyl hindered phenols
US5488145A (en) *	1993-12-23	1996-01-30	Oklahoma Medical Research Foundation	2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
EP0888290B1 (fr) *	1995-11-17	2006-12-27	Florida International University	Agents de piegeage de spin a base d'azulenyl-nitrones, et leurs procedes de fabrication et d'utilisation
JP2000514822A (ja) *	1996-07-19	2000-11-07	センターファーマシューティカルズ，インコーポレイテッド	フランニトロン化合物
TW429241B (en) *	1996-09-26	2001-04-11	Sumitomo Pharma	Nitrone derivatives

1999
- 1999-01-14 EP EP99903086A patent/EP1047683A1/fr not_active Ceased
- 1999-01-14 AU AU23192/99A patent/AU742768B2/en not_active Ceased
- 1999-01-14 JP JP2000540131A patent/JP2002509143A/ja not_active Withdrawn
- 1999-01-14 NZ NZ505757A patent/NZ505757A/xx unknown
- 1999-01-14 ZA ZA9900252A patent/ZA99252B/xx unknown
- 1999-01-14 WO PCT/US1999/000785 patent/WO1999036415A1/fr not_active Ceased
- 1999-01-14 CN CN99803302A patent/CN1291980A/zh active Pending
- 1999-01-14 CA CA002318357A patent/CA2318357A1/fr not_active Abandoned
- 1999-01-14 US US09/245,130 patent/US5998469A/en not_active Expired - Fee Related
- 1999-01-15 TW TW088100606A patent/TW446703B/zh not_active IP Right Cessation
- 1999-09-29 US US09/408,126 patent/US6127408A/en not_active Expired - Fee Related
2000
- 2000-02-17 US US09/505,716 patent/US6310092B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
TW446703B (en)	2001-07-21
US5998469A (en)	1999-12-07
CN1291980A (zh)	2001-04-18
JP2002509143A (ja)	2002-03-26
US6127408A (en)	2000-10-03
US6310092B1 (en)	2001-10-30
CA2318357A1 (fr)	1999-07-22
WO1999036415A1 (fr)	1999-07-22
NZ505757A (en)	2002-09-27
EP1047683A1 (fr)	2000-11-02
AU2319299A (en)	1999-08-02
AU742768B2 (en)	2002-01-10

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