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ZA994406B - Meta-azacyclic amino benzoic acid and derivatives thereof. - Google Patents

Meta-azacyclic amino benzoic acid and derivatives thereof.

Info

Publication number
ZA994406B
ZA994406B ZA9904406A ZA994406A ZA994406B ZA 994406 B ZA994406 B ZA 994406B ZA 9904406 A ZA9904406 A ZA 9904406A ZA 994406 A ZA994406 A ZA 994406A ZA 994406 B ZA994406 B ZA 994406B
Authority
ZA
South Africa
Prior art keywords
meta
derivatives
benzoic acid
amino benzoic
azacyclic amino
Prior art date
Application number
ZA9904406A
Inventor
Thomas E Rogers
Peter G Ruminski
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of ZA994406B publication Critical patent/ZA994406B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12Nitrogen atoms not forming part of a nitro radical
    • C07D239/14Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
ZA9904406A 1998-03-04 1999-02-11 Meta-azacyclic amino benzoic acid and derivatives thereof. ZA994406B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3427098A 1998-03-04 1998-03-04

Publications (1)

Publication Number Publication Date
ZA994406B true ZA994406B (en) 2000-02-11

Family

ID=21875345

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9904406A ZA994406B (en) 1998-03-04 1999-02-11 Meta-azacyclic amino benzoic acid and derivatives thereof.

Country Status (29)

Country Link
EP (1) EP1060164A1 (en)
JP (1) JP2002505323A (en)
KR (1) KR20010041584A (en)
CN (1) CN1214011C (en)
AP (1) AP1244A (en)
AR (1) AR018139A1 (en)
AU (1) AU753230B2 (en)
BG (1) BG104740A (en)
BR (1) BR9908470A (en)
CA (1) CA2322207A1 (en)
EA (1) EA200000804A1 (en)
EE (1) EE200000506A (en)
GE (1) GEP20033118B (en)
HR (1) HRP20000574A2 (en)
HU (1) HUP0100865A3 (en)
ID (1) ID25591A (en)
IL (1) IL137653A0 (en)
IS (1) IS5582A (en)
MY (1) MY123908A (en)
NO (1) NO315703B1 (en)
NZ (1) NZ506598A (en)
OA (1) OA11530A (en)
PL (1) PL342726A1 (en)
SK (1) SK13002000A3 (en)
TR (1) TR200002542T2 (en)
UA (1) UA71906C2 (en)
WO (1) WO1999044994A1 (en)
YU (1) YU52000A (en)
ZA (1) ZA994406B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9805655D0 (en) 1998-03-16 1998-05-13 Celltech Therapeutics Ltd Chemical compounds
GB9814414D0 (en) 1998-07-03 1998-09-02 Celltech Therapeutics Ltd Chemical compounds
GB9821061D0 (en) 1998-09-28 1998-11-18 Celltech Therapeutics Ltd Chemical compounds
GB9826174D0 (en) 1998-11-30 1999-01-20 Celltech Therapeutics Ltd Chemical compounds
US6518283B1 (en) 1999-05-28 2003-02-11 Celltech R&D Limited Squaric acid derivatives
US6455539B2 (en) 1999-12-23 2002-09-24 Celltech R&D Limited Squaric acid derivates
EP1332132B1 (en) 2000-04-17 2007-10-10 UCB Pharma, S.A. Enamine derivatives as cell adhesion molecules
US6403608B1 (en) 2000-05-30 2002-06-11 Celltech R&D, Ltd. 3-Substituted isoquinolin-1-yl derivatives
US6545013B2 (en) 2000-05-30 2003-04-08 Celltech R&D Limited 2,7-naphthyridine derivatives
US6921767B2 (en) * 2000-06-15 2005-07-26 Pharmacia Corporation Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
WO2002010136A1 (en) 2000-08-02 2002-02-07 Celltech R & D Limited 3-substituted isoquinolin-1-yl derivatives
JP2006514050A (en) * 2002-12-20 2006-04-27 ファルマシア・コーポレーション R isomers of β-amino acid compounds as integrin receptor antagonist derivatives
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
US20070015814A1 (en) * 2005-06-10 2007-01-18 Ernest Kun Parp Modulators and Treatment of Cancer
WO2008108944A2 (en) 2007-03-01 2008-09-12 Mallinckrodt Inc. Integrated photoactive small molecules and uses thereof
JP4792124B1 (en) * 2010-11-15 2011-10-12 エフイートレード株式会社 Method for molding protective film for vehicle and method for manufacturing protective film for vehicle
CN104640857B (en) 2012-07-18 2017-07-04 圣路易斯大学 As the beta amino acids derivative of integrin antagonists
US8716226B2 (en) 2012-07-18 2014-05-06 Saint Louis University 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists
JP6649902B2 (en) 2014-05-30 2020-02-19 ファイザー・インク Carbonitrile derivatives as selective androgen receptor modulators
ES2757074T3 (en) * 2014-06-04 2020-04-28 Monsanto Technology Llc 3,6-Dichlorosalicylic Acid Compounds and Related Synthetic Procedures
HK1244806A1 (en) 2015-12-30 2018-08-17 Saint Louis University Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
EP4151632A4 (en) 2020-05-14 2024-04-24 UBE Corporation 1,4,5,6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators
EP4431098A4 (en) 2021-11-12 2025-10-08 Ube Corp Pharmaceutical composition for the treatment of Alport syndrome

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU702487B2 (en) * 1995-08-30 1999-02-25 G.D. Searle & Co. Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid derivatives as integrin antagonists

Also Published As

Publication number Publication date
AP1244A (en) 2004-02-04
HUP0100865A3 (en) 2001-11-28
WO1999044994A1 (en) 1999-09-10
HRP20000574A2 (en) 2001-08-31
PL342726A1 (en) 2001-07-02
KR20010041584A (en) 2001-05-25
MY123908A (en) 2006-06-30
EP1060164A1 (en) 2000-12-20
AR018139A1 (en) 2001-10-31
CA2322207A1 (en) 1999-09-10
IS5582A (en) 2000-08-04
BR9908470A (en) 2000-12-05
CN1291978A (en) 2001-04-18
NZ506598A (en) 2003-07-25
UA71906C2 (en) 2005-01-17
OA11530A (en) 2004-05-17
YU52000A (en) 2003-02-28
AU753230B2 (en) 2002-10-10
AU3294799A (en) 1999-09-20
ID25591A (en) 2000-10-19
EE200000506A (en) 2002-04-15
IL137653A0 (en) 2001-10-31
AP2000001893A0 (en) 2000-09-30
CN1214011C (en) 2005-08-10
NO315703B1 (en) 2003-10-13
NO20004316D0 (en) 2000-08-30
GEP20033118B (en) 2003-11-25
TR200002542T2 (en) 2001-05-21
HUP0100865A2 (en) 2001-08-28
SK13002000A3 (en) 2001-07-10
JP2002505323A (en) 2002-02-19
BG104740A (en) 2001-02-28
NO20004316L (en) 2000-11-06
EA200000804A1 (en) 2001-04-23

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