|
TW321649B
(en)
*
|
1994-11-12 |
1997-12-01 |
Zeneca Ltd |
|
|
GB9424233D0
(en)
*
|
1994-11-30 |
1995-01-18 |
Zeneca Ltd |
Quinazoline derivatives
|
|
GB9508538D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
WO1996033977A1
(en)
*
|
1995-04-27 |
1996-10-31 |
Zeneca Limited |
Quinazoline derivatives
|
|
GB9508535D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivative
|
|
GB9508565D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quiazoline derivative
|
|
GB9508537D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
GB9624482D0
(en)
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
|
CA2242425C
(en)
|
1996-02-13 |
2006-07-18 |
Zeneca Limited |
Quinazoline derivatives as vegf inhibitors
|
|
GB9603097D0
(en)
*
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline compounds
|
|
GB9603095D0
(en)
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline derivatives
|
|
DE69709319T2
(en)
|
1996-03-05 |
2002-08-14 |
Astrazeneca Ab, Soedertaelje |
4-ANILINOQUINAZOLINE DERIVATIVES
|
|
ES2174250T5
(en)
|
1996-04-12 |
2010-04-21 |
Warner-Lambert Company Llc |
IRREVERSIBLE THYROSINE KINASE INHIBITORS.
|
|
GB9607729D0
(en)
*
|
1996-04-13 |
1996-06-19 |
Zeneca Ltd |
Quinazoline derivatives
|
|
GB9707800D0
(en)
|
1996-05-06 |
1997-06-04 |
Zeneca Ltd |
Chemical compounds
|
|
EP0912559B1
(en)
*
|
1996-07-13 |
2002-11-06 |
Glaxo Group Limited |
Fused heterocyclic compounds as protein tyrosine kinase inhibitors
|
|
US6310211B1
(en)
|
1996-09-10 |
2001-10-30 |
Pharmacia & Upjohn Company |
8-hydroxy-7-substituted quinolines as anti-viral agents
|
|
GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
|
ATE300521T1
(en)
*
|
1996-09-25 |
2005-08-15 |
Astrazeneca Ab |
QUINOLINE DERIVATIVES THAT DELAY THE EFFECT OF GROWTH FACTORS LIKE VEGF
|
|
US7863444B2
(en)
|
1997-03-19 |
2011-01-04 |
Abbott Laboratories |
4-aminopyrrolopyrimidines as kinase inhibitors
|
|
AU8071698A
(en)
*
|
1997-06-13 |
1998-12-30 |
Sugen, Inc. |
Novel heteroaryl compounds for the modulation of protein tyrosine enzyme relatedcellular signal transduction
|
|
WO1999010349A1
(en)
|
1997-08-22 |
1999-03-04 |
Zeneca Limited |
Oxindolylquinazoline derivatives as angiogenesis inhibitors
|
|
GB9800569D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
GB9800575D0
(en)
*
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
US6706721B1
(en)
|
1998-04-29 |
2004-03-16 |
Osi Pharmaceuticals, Inc. |
N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
|
|
HUP0103386A3
(en)
*
|
1998-08-21 |
2002-07-29 |
Parker Hughes Inst St Paul |
Use of quinazoline derivatives for producing pharmaceutical compositions having jak 3-inhibitor effect
|
|
US6184226B1
(en)
|
1998-08-28 |
2001-02-06 |
Scios Inc. |
Quinazoline derivatives as inhibitors of P-38 α
|
|
US6713474B2
(en)
|
1998-09-18 |
2004-03-30 |
Abbott Gmbh & Co. Kg |
Pyrrolopyrimidines as therapeutic agents
|
|
ATE294796T1
(en)
|
1998-10-08 |
2005-05-15 |
Astrazeneca Ab |
QUINAZOLINE DERIVATIVES
|
|
GB9822450D0
(en)
*
|
1998-10-14 |
1998-12-09 |
Smithkline Beecham Plc |
Medicaments
|
|
ATE556713T1
(en)
|
1999-01-13 |
2012-05-15 |
Bayer Healthcare Llc |
OMEGA-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS P38 KINASE INHIBITORS
|
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
AU2437900A
(en)
*
|
1999-01-20 |
2000-08-07 |
Smithkline Beecham Plc |
Piperidinylquinolines as protein tyrosine kinase inhibitors
|
|
EE05345B1
(en)
|
1999-02-10 |
2010-10-15 |
Astrazeneca Ab |
Quinazoline derivatives as inhibitors of angiogenesis
|
|
GB9904103D0
(en)
|
1999-02-24 |
1999-04-14 |
Zeneca Ltd |
Quinoline derivatives
|
|
GB9910580D0
(en)
|
1999-05-08 |
1999-07-07 |
Zeneca Ltd |
Chemical compounds
|
|
GB9910579D0
(en)
|
1999-05-08 |
1999-07-07 |
Zeneca Ltd |
Chemical compounds
|
|
GB9914486D0
(en)
|
1999-06-21 |
1999-08-18 |
Smithkline Beecham Plc |
Medicaments
|
|
TWI262914B
(en)
*
|
1999-07-02 |
2006-10-01 |
Agouron Pharma |
Compounds and pharmaceutical compositions for inhibiting protein kinases
|
|
IL147280A0
(en)
|
1999-07-07 |
2002-08-14 |
Astrazeneca Uk Ltd |
Quinazoline derivatives
|
|
US6933299B1
(en)
|
1999-07-09 |
2005-08-23 |
Smithkline Beecham Corporation |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
|
JP2003504363A
(en)
*
|
1999-07-09 |
2003-02-04 |
グラクソ グループ リミテッド |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
|
GB9917406D0
(en)
|
1999-07-23 |
1999-09-22 |
Smithkline Beecham Plc |
Compounds
|
|
GB9917408D0
(en)
|
1999-07-23 |
1999-09-22 |
Smithkline Beecham Plc |
Compounds
|
|
DE60004685T2
(en)
|
1999-09-17 |
2004-07-29 |
Abbott Gmbh & Co. Kg |
PYRAZOLOPYRIMIDINE AS A MEDICINAL PRODUCT
|
|
US7071199B1
(en)
|
1999-09-17 |
2006-07-04 |
Abbott Gmbh & Cco. Kg |
Kinase inhibitors as therapeutic agents
|
|
KR100881105B1
(en)
|
1999-11-05 |
2009-02-02 |
아스트라제네카 아베 |
Quinazolin Derivatives as VEGF Inhibitors
|
|
UA74803C2
(en)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
A stable polymorph of n-(3-ethynylphenyl)-6,7-bis(2-methoxyetoxy)-4-quinazolinamine hydrochloride, a method for producing thereof (variants) and pharmaceutical use
|
|
US7087613B2
(en)
|
1999-11-11 |
2006-08-08 |
Osi Pharmaceuticals, Inc. |
Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
|
|
DE60112268T2
(en)
|
2000-03-06 |
2006-05-24 |
Astrazeneca Ab |
USE OF QUINAZOLIN DERIVATIVES AS INHIBITORS OF ANGIOGENESIS
|
|
US20030152572A1
(en)
*
|
2000-04-06 |
2003-08-14 |
Yoshimi Homma |
Diagnostic and therapeutic agents for rheumatoid arthritis
|
|
DE60121931T2
(en)
|
2000-04-07 |
2007-03-01 |
Astrazeneca Ab |
quinazoline
|
|
UA73993C2
(en)
|
2000-06-06 |
2005-10-17 |
Астразенека Аб |
Quinazoline derivatives for the treatment of tumours and a pharmaceutical composition
|
|
AU7425801A
(en)
|
2000-06-24 |
2002-01-08 |
Astrazeneca Ab |
Guanidine derivatives of quinazoline and quinoline for use in the treatment of autoimmune diseases
|
|
EP1299381B1
(en)
*
|
2000-06-28 |
2008-05-07 |
AstraZeneca AB |
Substituted quinazoline derivatives and their use as inhibitors
|
|
PL366335A1
(en)
|
2000-07-26 |
2005-01-24 |
Smithkline Beecham P.L.C. |
Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
|
|
MXPA03000252A
(en)
|
2000-08-09 |
2003-06-06 |
Astrazeneca Ab |
Quinoline derivatives having vegf inhibiting activity.
|
|
AU2001278609B2
(en)
|
2000-08-21 |
2005-04-14 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
ATE448226T1
(en)
|
2000-09-01 |
2009-11-15 |
Novartis Vaccines & Diagnostic |
AZA HETEROCYCLIC DERIVATIVES AND THEIR THERAPEUTIC USE
|
|
KR100732206B1
(en)
|
2000-09-11 |
2007-06-27 |
노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 |
Quinolinone Derivatives as Tyrosine Kinase Inhibitors
|
|
CN1474815A
(en)
|
2000-09-20 |
2004-02-11 |
Ĭ��ר���ɷ�����˾ |
4-amino-quinazoline
|
|
JP2004511479A
(en)
|
2000-10-13 |
2004-04-15 |
アストラゼネカ アクチボラグ |
Quinazoline derivatives
|
|
HU230302B1
(en)
|
2000-10-20 |
2015-12-28 |
Eisai R&D Management Co., Ltd. |
Nitrogenous aromatic ring compounds and pharmaceutical compositions containing them
|
|
EP1332141A1
(en)
*
|
2000-10-25 |
2003-08-06 |
AstraZeneca AB |
Quinazoline derivatives
|
|
EP1330444B1
(en)
|
2000-11-01 |
2011-03-23 |
Millennium Pharmaceuticals, Inc. |
Nitrogenous heterocyclic compounds and process for making them
|
|
AU2001295791A1
(en)
|
2000-11-02 |
2002-05-15 |
Astrazeneca Ab |
4-substituted quinolines as antitumor agents
|
|
EP1337524A1
(en)
|
2000-11-02 |
2003-08-27 |
AstraZeneca AB |
Substituted quinolines as antitumor agents
|
|
GB0101577D0
(en)
|
2001-01-22 |
2001-03-07 |
Smithkline Beecham Plc |
Compounds
|
|
DE60218138T2
(en)
*
|
2001-03-23 |
2007-09-20 |
Bayer Pharmaceuticals Corp., West Haven |
RHO-KINASE INHIBITORS
|
|
PE20021011A1
(en)
*
|
2001-03-23 |
2003-02-01 |
Bayer Corp |
QUINAZOLINE DERIVATIVES AS INHIBITORS OF RHO-KINASE
|
|
CA2440842A1
(en)
|
2001-04-16 |
2002-10-24 |
Eisai Co., Ltd. |
Novel 1h-indazole compounds
|
|
WO2002085895A1
(en)
|
2001-04-19 |
2002-10-31 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
GB0112834D0
(en)
|
2001-05-25 |
2001-07-18 |
Smithkline Beecham Plc |
Medicaments
|
|
US7829566B2
(en)
|
2001-09-17 |
2010-11-09 |
Werner Mederski |
4-amino-quinazolines
|
|
KR100810468B1
(en)
*
|
2001-10-10 |
2008-03-07 |
씨제이제일제당 (주) |
1H-indole derivative having excellent selectivity as an inhibitor of cyclooxygenase-2
|
|
GB0126433D0
(en)
*
|
2001-11-03 |
2002-01-02 |
Astrazeneca Ab |
Compounds
|
|
WO2003040108A1
(en)
*
|
2001-11-03 |
2003-05-15 |
Astrazeneca Ab |
Quinazoline derivatives as antitumor agents
|
|
WO2003055866A1
(en)
*
|
2001-12-21 |
2003-07-10 |
Bayer Pharmaceuticals Corporation |
Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
|
|
SI1463506T1
(en)
|
2001-12-24 |
2010-01-29 |
Astrazeneca Ab |
Substituted quinazoline derivatives as inhibitors of aurora kinases
|
|
ES2305435T3
(en)
|
2002-01-10 |
2008-11-01 |
Bayer Healthcare Ag |
INHIBITORS OF RHO-QUINASA.
|
|
JP4469179B2
(en)
|
2002-01-23 |
2010-05-26 |
バイエル ファーマセチカル コーポレーション |
Pyrimidine derivatives as Rho kinase inhibitors
|
|
JP4423043B2
(en)
|
2002-01-23 |
2010-03-03 |
バイエル ファーマセチカル コーポレーション |
Rho-kinase inhibitor
|
|
JP4445753B2
(en)
|
2002-01-29 |
2010-04-07 |
グラクソ グループ リミテッド |
Aminopiperidine derivatives
|
|
EP1470131A2
(en)
|
2002-01-29 |
2004-10-27 |
Glaxo Group Limited |
Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
|
|
MXPA04007459A
(en)
*
|
2002-02-01 |
2005-09-08 |
Astrazeneca Ab |
Quinazoline compounds.
|
|
AU2003209116A1
(en)
|
2002-02-11 |
2003-09-04 |
Bayer Pharmaceuticals Corporation |
Aryl ureas with angiogenesis inhibiting activity
|
|
TW200302722A
(en)
*
|
2002-02-13 |
2003-08-16 |
Astrazeneca Ab |
Therapeutic agents
|
|
US7645878B2
(en)
*
|
2002-03-22 |
2010-01-12 |
Bayer Healthcare Llc |
Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof
|
|
US6924285B2
(en)
|
2002-03-30 |
2005-08-02 |
Boehringer Ingelheim Pharma Gmbh & Co. |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
|
GB0215823D0
(en)
|
2002-07-09 |
2002-08-14 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
WO2004004732A1
(en)
|
2002-07-09 |
2004-01-15 |
Astrazeneca Ab |
Quinazoline derivatives for use in the treatment of cancer
|
|
WO2004006846A2
(en)
|
2002-07-15 |
2004-01-22 |
Exelixis, Inc. |
Receptor-type kinase modulators and methods of use
|
|
CA2494061C
(en)
|
2002-07-31 |
2011-06-14 |
Wayne R. Danter |
Protein tyrosine kinase inhibitors
|
|
US7470709B2
(en)
|
2002-08-23 |
2008-12-30 |
Novartis Vaccines And Diagnostics, Inc. |
Benzimidazole quinolinones and uses thereof
|
|
US7825132B2
(en)
|
2002-08-23 |
2010-11-02 |
Novartis Vaccines And Diagnostics, Inc. |
Inhibition of FGFR3 and treatment of multiple myeloma
|
|
WO2004033446A1
(en)
|
2002-10-09 |
2004-04-22 |
Danter Wayne R |
Protein tyrosine kinase inhibitors
|
|
EP1581217A4
(en)
*
|
2002-11-01 |
2007-07-11 |
Merck & Co Inc |
CARBONYLAMINO-BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF THE ANDROGEN RECEPTOR
|
|
GB0225579D0
(en)
|
2002-11-02 |
2002-12-11 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2004041829A1
(en)
|
2002-11-04 |
2004-05-21 |
Astrazeneca Ab |
Quinazoline derivatives as src tyrosine kinase inhibitors
|
|
CN100354278C
(en)
*
|
2002-11-04 |
2007-12-12 |
阿斯利康(瑞典)有限公司 |
Quinazoline derivatives as SRC tyrosine kinase inhibitors
|
|
JP2006511616A
(en)
|
2002-11-13 |
2006-04-06 |
カイロン コーポレイション |
Methods for treating cancer and related methods
|
|
US7429597B2
(en)
|
2002-12-23 |
2008-09-30 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
Substituted nitrogen-containing heterobicycles, the preparation thereof and their use as pharmaceutical compositions
|
|
DE10260730A1
(en)
|
2002-12-23 |
2004-07-01 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Novel substituted nitrogen-containing heterobicyclene, their preparation and their use as pharmaceuticals
|
|
ATE438644T1
(en)
|
2002-12-24 |
2009-08-15 |
Astrazeneca Ab |
CHINAZOLINE DERIVATIVES
|
|
GB0307333D0
(en)
*
|
2003-03-29 |
2003-05-07 |
Astrazeneca Ab |
Therapeutic agent
|
|
GB0309009D0
(en)
*
|
2003-04-22 |
2003-05-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
GB0309850D0
(en)
|
2003-04-30 |
2003-06-04 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
PT1636585E
(en)
|
2003-05-20 |
2008-03-27 |
Bayer Pharmaceuticals Corp |
Diaryl ureas with kinase inhibiting activity
|
|
GB0317665D0
(en)
|
2003-07-29 |
2003-09-03 |
Astrazeneca Ab |
Qinazoline derivatives
|
|
GB0318422D0
(en)
*
|
2003-08-06 |
2003-09-10 |
Astrazeneca Ab |
Chemical compounds
|
|
ATE395346T1
(en)
|
2003-09-16 |
2008-05-15 |
Astrazeneca Ab |
QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS
|
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
CA2744997A1
(en)
|
2003-09-26 |
2005-04-07 |
Exelixis, Inc. |
C-met modulators and method of use
|
|
CN100450998C
(en)
|
2003-11-11 |
2009-01-14 |
卫材R&D管理有限公司 |
Process for the preparation of urea derivatives
|
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
GEP20084572B
(en)
|
2003-12-23 |
2008-12-25 |
Pfizer |
Novel quinoline derivatives
|
|
GB0330042D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions them
|
|
GB0330043D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
|
|
GB0330002D0
(en)
|
2003-12-24 |
2004-01-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
UA86614C2
(en)
|
2004-01-23 |
2009-05-12 |
Амген Инк |
Compound having kinase ingibitor activity, pharmaceutical composition containing thereof and use thereof for the preparation of medicine
|
|
EP1711495A2
(en)
*
|
2004-01-23 |
2006-10-18 |
Amgen Inc. |
Quinoline, quinazoline, pyridine and pyrimidine counds and their use in the treatment of inflammation, angiogenesis and cancer
|
|
ES2315834T3
(en)
|
2004-02-03 |
2009-04-01 |
Astrazeneca Ab |
DERIVATIVES OF QUINAZOLINA.
|
|
CN1960731B
(en)
|
2004-02-20 |
2011-12-07 |
诺华疫苗和诊断公司 |
Method for regulating inflammatory and metastatic processes
|
|
SI1746999T1
(en)
|
2004-05-06 |
2012-01-31 |
Warner Lambert Co |
4-phenylamino-quinazolin-6-yl-amides
|
|
CA2567832A1
(en)
*
|
2004-06-04 |
2005-12-15 |
Astrazeneca Ab |
Quinazoline derivatives as erbb receptor tyrosine kinases
|
|
WO2005120509A1
(en)
|
2004-06-04 |
2005-12-22 |
Amphora Discovery Corporation |
Quinoline- and isoquinoline-based compounds exhibiting atp-utilizing enzyme inhibitory activity, and compositions, and uses thereof
|
|
EP1797881B1
(en)
|
2004-09-17 |
2009-04-15 |
Eisai R&D Management Co., Ltd. |
Medicinal composition with improved stability and reduced gelation properties
|
|
MX2007004403A
(en)
|
2004-10-12 |
2007-04-27 |
Astrazeneca Ab |
Quinazoline derivatives.
|
|
AU2005312048B2
(en)
|
2004-11-30 |
2012-08-02 |
Amgen Inc. |
Quinolines and quinazoline analogs and their use as medicaments for treating cancer
|
|
US7947676B2
(en)
|
2004-12-14 |
2011-05-24 |
Astrazeneca Ab |
Pyrazolo[3,4-d]pyrimidine compounds as antitumor agents
|
|
DE602006004976D1
(en)
|
2005-03-28 |
2009-03-12 |
Bristol Myers Squibb Co |
COMPETITIVE ATP KINASE HEMMER
|
|
JO2787B1
(en)
|
2005-04-27 |
2014-03-15 |
امجين إنك, |
Substituted Amid derivatives & methods of use
|
|
GB0508715D0
(en)
*
|
2005-04-29 |
2005-06-08 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2006124413A2
(en)
|
2005-05-13 |
2006-11-23 |
Novartis Ag |
Methods for treating drug resistant cancer
|
|
BRPI0610355A2
(en)
|
2005-05-17 |
2010-06-15 |
Novartis Ag |
methods to synthesize heterocyclic compounds
|
|
EP2270000B1
(en)
|
2005-05-23 |
2015-07-29 |
Novartis AG |
Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one lactic acid salts
|
|
WO2007011623A1
(en)
*
|
2005-07-15 |
2007-01-25 |
Schering Corporation |
Quinazoline derivatives useful in cancer treatment
|
|
EP2281901B1
(en)
|
2005-08-02 |
2013-11-27 |
Eisai R&D Management Co., Ltd. |
Anti-tumour pharmaceutical composition with angiogenesis inhibitors
|
|
TW200804345A
(en)
|
2005-08-30 |
2008-01-16 |
Novartis Ag |
Substituted benzimidazoles and methods of preparation
|
|
DE602006018331D1
(en)
|
2005-09-20 |
2010-12-30 |
Astrazeneca Ab |
4- (1H-INDAZOL-5-YLAMINO) CHINAZOLINE COMPOUNDS AS INHIBITORS OF ERBB RECEPTORT ROSINKINASE FOR THE TREATMENT OF CANCER
|
|
CA2641744C
(en)
|
2006-02-10 |
2012-09-25 |
Transtech Pharma, Inc. |
Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors
|
|
UY30183A1
(en)
|
2006-03-02 |
2007-10-31 |
Astrazeneca Ab |
QUINOLINE DERIVATIVES
|
|
EP2036557B1
(en)
|
2006-05-18 |
2015-10-21 |
Eisai R&D Management Co., Ltd. |
Antitumor agent for thyroid cancer
|
|
CN101511793B
(en)
|
2006-08-28 |
2011-08-03 |
卫材R&D管理有限公司 |
Antineoplastic agents against undifferentiated gastric cancer
|
|
EP1921070A1
(en)
|
2006-11-10 |
2008-05-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Bicyclic heterocycles, medicaments comprising them, their use and process for their preparation
|
|
AU2008211952B2
(en)
|
2007-01-29 |
2012-07-19 |
Eisai R & D Management Co., Ltd. |
Composition for treatment of undifferentiated-type of gastric cancer
|
|
EA200901041A1
(en)
|
2007-02-06 |
2010-02-26 |
Бёрингер Ингельхайм Интернациональ Гмбх |
BICYCLIC HETEROCYCLES CONTAINING THESE COMPOUNDS MEDICINES, THEIR APPLICATION AND METHOD OF OBTAINING THEM
|
|
JP5438008B2
(en)
*
|
2007-09-21 |
2014-03-12 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
Inhibitors of the interaction between MDM2 and p53
|
|
US7795254B2
(en)
|
2007-10-29 |
2010-09-14 |
Amgen Inc. |
Benzomorpholine derivatives and methods of use
|
|
EA018716B1
(en)
|
2007-10-29 |
2013-10-30 |
Натко Фарма Лимитед |
Novel 4-(tetrazol-5-yl)quinazoline derivatives as anti cancer agents
|
|
JP5638244B2
(en)
|
2007-11-09 |
2014-12-10 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
Combination of angiogenesis inhibitors and antitumor platinum complexes
|
|
CA2710039C
(en)
|
2007-12-26 |
2018-07-03 |
Critical Outcome Technologies, Inc. |
Semicarbazones, thiosemicarbazones and related compounds and methods for treatment of cancer
|
|
PL2245026T3
(en)
|
2008-02-07 |
2013-01-31 |
Boehringer Ingelheim Int |
Spirocyclic heterocycles, medicaments containing said compounds, use thereof and method for their production
|
|
ES2444128T3
(en)
|
2008-05-13 |
2014-02-24 |
Astrazeneca Ab |
New SAL-554
|
|
WO2010006438A1
(en)
|
2008-07-17 |
2010-01-21 |
Critical Outcome Technologies Inc. |
Thiosemicarbazone inhibitor compounds and cancer treatment methods
|
|
JP5539351B2
(en)
|
2008-08-08 |
2014-07-02 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cyclohexyloxy-substituted heterocycles, medicaments containing these compounds, and methods for producing them
|
|
KR101733773B1
(en)
|
2009-01-16 |
2017-05-10 |
엑셀리시스, 인코포레이티드 |
The end of N- (4 - {[6,7-bis (methyloxy) quinolin-4-yl] oxy} phenyl) -N '- (4-fluorophenyl) cyclopropane-1,1-dicarboxamide Acid salts and their crystalline forms
|
|
UA108618C2
(en)
|
2009-08-07 |
2015-05-25 |
|
APPLICATION OF C-MET-MODULATORS IN COMBINATION WITH THEMOSOLOMID AND / OR RADIATION THERAPY FOR CANCER TREATMENT
|
|
ES2900504T3
(en)
|
2009-09-03 |
2022-03-17 |
Bristol Myers Squibb Co |
Quinazolines as inhibitors of potassium ion channels
|
|
US8987272B2
(en)
|
2010-04-01 |
2015-03-24 |
Critical Outcome Technologies Inc. |
Compounds and method for treatment of HIV
|
|
MX2012014776A
(en)
|
2010-06-25 |
2013-01-29 |
Eisai R&D Man Co Ltd |
Antitumor agent using compounds having kinase inhibitory effect in combination.
|
|
EP2598497B1
(en)
*
|
2010-07-29 |
2019-03-06 |
Merck Patent GmbH |
Cyclic amine azaheterocyclic carboxamides
|
|
KR20210043016A
(en)
|
2011-03-04 |
2021-04-20 |
뉴젠 세러퓨틱스 인코포레이티드 |
Alkyne substituted quinazoline compound and methods of use
|
|
MX2013009931A
(en)
|
2011-04-18 |
2013-10-01 |
Eisai R&D Man Co Ltd |
Therapeutic agent for tumor.
|
|
US9945862B2
(en)
|
2011-06-03 |
2018-04-17 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
|
CN102942561A
(en)
*
|
2012-11-06 |
2013-02-27 |
深圳海王药业有限公司 |
4-amino quinazoline heterocyclic compound and purpose of 4-amino quinazoline heterocyclic compound
|
|
US9334239B2
(en)
|
2012-12-21 |
2016-05-10 |
Eisai R&D Management Co., Ltd. |
Amorphous form of quinoline derivative, and method for producing same
|
|
JP6669499B2
(en)
|
2013-02-15 |
2020-03-18 |
カラ ファーマシューティカルズ インコーポレイテッド |
Therapeutic compounds
|
|
US9688688B2
(en)
|
2013-02-20 |
2017-06-27 |
Kala Pharmaceuticals, Inc. |
Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
|
|
WO2014130612A1
(en)
|
2013-02-20 |
2014-08-28 |
Kala Pharmaceuticals, Inc. |
Therapeutic compounds and uses thereof
|
|
BR112015024971B1
(en)
|
2013-04-04 |
2022-09-20 |
Janssen Pharmaceutica Nv |
N-(2,3-DIHYDRO-1H-PYROLO[2,3-B]PYRIDIN-5-IL)-4-QUINAZOLINAMINE AND N-(2,3-DIHYDRO-1HINDOL-5-IL) DERIVATIVES )-4-QUINAZOLINAMINE AS PERK INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING THEM
|
|
US10517861B2
(en)
|
2013-05-14 |
2019-12-31 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
|
TW201534597A
(en)
|
2013-06-20 |
2015-09-16 |
Ab Science |
Benzimidazole derivatives as selective proteine kinase inhibitors
|
|
LT3046584T
(en)
|
2013-09-16 |
2017-10-10 |
Astrazeneca Ab |
Therapeutic polymeric nanoparticles and methods of making and using same
|
|
CN108530458A
(en)
|
2013-11-01 |
2018-09-14 |
卡拉制药公司 |
Crystal form of therapeutic compounds and application thereof
|
|
US9890173B2
(en)
|
2013-11-01 |
2018-02-13 |
Kala Pharmaceuticals, Inc. |
Crystalline forms of therapeutic compounds and uses thereof
|
|
DK3126330T3
(en)
*
|
2014-04-04 |
2019-04-23 |
Pfizer |
BICYCLE-FUSED HETEROARYL OR ARYL COMPOUNDS AND USE THEREOF AS IRAC4 INHIBITORS
|
|
CN106660964B
(en)
|
2014-08-28 |
2021-09-03 |
卫材R&D管理有限公司 |
High-purity quinoline derivative and process for producing the same
|
|
PL3263106T3
(en)
|
2015-02-25 |
2024-04-02 |
Eisai R&D Management Co., Ltd. |
Method for suppressing bitterness of quinoline derivative
|
|
KR102662228B1
(en)
|
2015-03-04 |
2024-05-02 |
머크 샤프 앤드 돔 코포레이션 |
Combination of PD-1 antagonists and VEGFR/FGFR/RET tyrosine kinase inhibitors to treat cancer
|
|
CN104725364B
(en)
*
|
2015-03-12 |
2017-09-15 |
江苏省中国科学院植物研究所 |
The amine derivative of 6,7 dimethoxyquinazoline 4, its preparation method and medical usage
|
|
ES2886107T3
(en)
|
2015-06-16 |
2021-12-16 |
Prism Biolab Co Ltd |
Antineoplastic
|
|
AU2016309356B2
(en)
|
2015-08-20 |
2021-06-24 |
Eisai R&D Management Co., Ltd. |
Tumor therapeutic agent
|
|
KR20180086187A
(en)
|
2015-10-05 |
2018-07-30 |
더 트러스티이스 오브 콜롬비아 유니버시티 인 더 시티 오브 뉴욕 |
Clearance of protein aggregates including phospholipase D and tau, and treatment of protein diseases
|
|
CN106045980B
(en)
*
|
2016-06-03 |
2017-11-03 |
江苏开放大学 |
A kind of quinazoline derivant and preparation method thereof
|
|
EP3509421A4
(en)
|
2016-09-08 |
2020-05-20 |
Kala Pharmaceuticals, Inc. |
Crystalline forms of therapeutic compounds and uses thereof
|
|
AU2017324713B2
(en)
|
2016-09-08 |
2020-08-13 |
KALA BIO, Inc. |
Crystalline forms of therapeutic compounds and uses thereof
|
|
EP3509423A4
(en)
|
2016-09-08 |
2020-05-13 |
Kala Pharmaceuticals, Inc. |
Crystalline forms of therapeutic compounds and uses thereof
|
|
MX380144B
(en)
|
2017-02-08 |
2025-03-12 |
Eisai R&D Man Co Ltd |
PHARMACEUTICAL COMPOSITION FOR TUMOR TREATMENT.
|
|
WO2018197643A1
(en)
*
|
2017-04-27 |
2018-11-01 |
Astrazeneca Ab |
Phenoxyquinazoline compounds and their use in treating cancer
|
|
EP3615522B1
(en)
|
2017-04-27 |
2021-08-04 |
Astrazeneca AB |
C5-anilinoquinazoline compounds and their use in treating cancer
|
|
CA3061888A1
(en)
|
2017-05-16 |
2018-11-22 |
Eisai R&D Management Co., Ltd. |
Treatment of hepatocellular carcinoma
|
|
US20200290978A1
(en)
*
|
2017-09-26 |
2020-09-17 |
The Regents Of The University Of California |
Compositions and methods for treating cancer
|
|
FR3080620B1
(en)
*
|
2018-04-27 |
2021-11-12 |
Univ Paris Sud |
COMPOUNDS WITH TUBULIN POLYMERIZATION INHIBITOR ACTIVITY AND IMMUNOMODULATORY PROPERTIES
|