ZA947659B - 3-(disubstitutedphenyl)cyclohexan-1-ones for use in treating asthma - Google Patents

3-(disubstitutedphenyl)cyclohexan-1-ones for use in treating asthma

Info

Publication number: ZA947659B
Authority: ZA; South Africa
Prior art keywords: disubstitutedphenyl; cyclohexan; ones; treating asthma; asthma
Prior art date: 1993-10-01

Application number

ZA947659A

Other languages

English (en)

Inventor

Siegfried Benjamin Christensen

Kevin Scott Webb

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-01

Filing date

1994-09-30

Publication date

1995-08-07

1994-09-30 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1995-08-07 Publication of ZA947659B publication Critical patent/ZA947659B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA947659A 1993-10-01 1994-09-30 3-(disubstitutedphenyl)cyclohexan-1-ones for use in treating asthma ZA947659B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US13021593A	1993-10-01	1993-10-01

Publications (1)

Publication Number	Publication Date
ZA947659B true ZA947659B (en)	1995-08-07

Family

ID=22443610

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA947659A ZA947659B (en)	1993-10-01	1994-09-30	3-(disubstitutedphenyl)cyclohexan-1-ones for use in treating asthma

Country Status (6)

Country	Link
EP (1)	EP0727990B1 (xx)
JP (1)	JPH09503505A (xx)
AU (1)	AU8011194A (xx)
DE (1)	DE69427485T2 (xx)
WO (1)	WO1995009624A1 (xx)
ZA (1)	ZA947659B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997048697A1 (en)	1996-06-19	1997-12-24	Rhone-Poulenc Rorer Limited	Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase
CZ302882B6 (cs)	1999-08-21	2012-01-04	Nycomed Gmbh	Farmaceutický prostredek
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
BRPI0409229A (pt)	2003-04-01	2006-03-28	Applied Research Systems	inibidores das fosfodiesterases na infertilidade
US20100120694A1 (en)	2008-06-04	2010-05-13	Synergy Pharmaceuticals, Inc.	Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP5546451B2 (ja)	2007-06-04	2014-07-09	シナジーファーマシューティカルズインコーポレイテッド	胃腸の障害、炎症、癌および他の障害の処置に有用なグアニル酸シクラーゼのアゴニスト
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh)	2011-03-01	2018-10-19	辛纳吉制药公司	制备鸟苷酸环化酶c激动剂的方法
EP3718557A3 (en)	2013-02-25	2020-10-21	Bausch Health Ireland Limited	Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing
HK1220696A1 (zh)	2013-03-15	2017-05-12	Bausch Health Ireland Limited	鸟苷酸环化酶激动剂及其用途
AU2014235209B2 (en)	2013-03-15	2018-06-14	Bausch Health Ireland Limited	Guanylate cyclase receptor agonists combined with other drugs
EP4424697A3 (en)	2013-06-05	2024-12-25	Bausch Health Ireland Limited	Ultra-pure agonists of guanylate cyclase c, method of making and using same
JP6694385B2 (ja)	2013-08-09	2020-05-13	アーデリクス，インコーポレーテッド	リン酸塩輸送阻害のための化合物及び方法
EP3972599B1 (en)	2019-05-21	2025-10-22	Ardelyx, Inc.	Combination for lowering serum phosphate in a patient

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69328778T2 (de) *	1992-04-02	2000-11-23	Smithkline Beecham Corp., Philadelphia	Verbindungen für die behandlung von entzündlichen erkrankungen und zur hemmung der produktion von tumornekrosefaktor
JP3192424B2 (ja) *	1992-04-02	2001-07-30	スミスクライン・ビーチャム・コーポレイション	アレルギーまたは炎症疾患の治療用化合物
WO1995003794A1 (en) *	1993-07-30	1995-02-09	Smithkline Beecham Corporation	3-cyano-3-(3,4-disubstituted)phenylcyclohexyl-1-carboxylates

1994
- 1994-09-23 WO PCT/US1994/010815 patent/WO1995009624A1/en not_active Ceased
- 1994-09-23 JP JP7510846A patent/JPH09503505A/ja not_active Ceased
- 1994-09-23 AU AU80111/94A patent/AU8011194A/en not_active Abandoned
- 1994-09-23 EP EP94931286A patent/EP0727990B1/en not_active Expired - Lifetime
- 1994-09-23 DE DE69427485T patent/DE69427485T2/de not_active Expired - Lifetime
- 1994-09-30 ZA ZA947659A patent/ZA947659B/xx unknown

Also Published As

Publication number	Publication date
EP0727990B1 (en)	2001-06-13
EP0727990A4 (en)	1999-03-10
DE69427485D1 (de)	2001-07-19
AU8011194A (en)	1995-05-01
JPH09503505A (ja)	1997-04-08
WO1995009624A1 (en)	1995-04-13
EP0727990A1 (en)	1996-08-28
DE69427485T2 (de)	2002-04-25

Publication	Publication Date	Title
EG24222A (en)	2008-11-10	Spiro-azabicyclic compounds useful in therapy
GB2276639B (en)	1996-05-01	Solutions for wood treatment and their preparation
ZA945089B (en)	1995-02-22	Air treatment apparatus
ZA947659B (en)	1995-08-07	3-(disubstitutedphenyl)cyclohexan-1-ones for use in treating asthma
GB2277450B (en)	1997-03-12	Device for use in lithotrity
HU9401228D0 (en)	1994-08-29	Grinding apparatus
AU7227394A (en)	1995-02-28	Method for surface treatment, means for carrying out the method and the use thereof
PL305419A1 (en)	1995-04-18	Drying apparatus for use in desulphurisation process
HUP9901177A3 (en)	2001-03-28	Fungicide mixtures and process for their use
GB2294105B (en)	1998-01-28	Improvements in decontamination
GB9411291D0 (en)	1994-07-27	Treatment apparatus
GB9320897D0 (en)	1993-12-01	Compounds useful in anti-allergy treatment
HU9500100D0 (en)	1995-03-28	Built in apparatus
ZA947658B (en)	1995-08-07	2-carbmethoxy-5-(disubstitutedphenyl)cyclohexan-1-ones and analogs thereof for use in treating asthma
GB2291971B (en)	1998-09-23	Apparatus for use in therapy
GB9324977D0 (en)	1994-01-26	Providing mecroorgansims for use in waste treatment
GB9404075D0 (en)	1994-03-03	Apparatus for use in the treatment of workpieces
GB9320773D0 (en)	1993-12-01	Game apparatus
GB9318116D0 (en)	1993-10-20	Compounds useful in therapy
GB9322790D0 (en)	1993-12-22	Compounds useful in therapy
GB9322864D0 (en)	1993-12-22	Compounds useful in therapy
GB9417084D0 (en)	1994-10-12	Compounds useful in therapy
GB9411293D0 (en)	1994-07-27	Compounds useful in therapy
GB9417501D0 (en)	1994-10-19	Compounds useful in therapy
GB9411244D0 (en)	1994-07-27	Compounds useful in therapy