ZA937604B - 3,3-disubstituted tri and tetracyclic indolin-2-ones useful for the treatment of cognitive disorders - Google Patents
3,3-disubstituted tri and tetracyclic indolin-2-ones useful for the treatment of cognitive disordersInfo
- Publication number
- ZA937604B ZA937604B ZA937604A ZA937604A ZA937604B ZA 937604 B ZA937604 B ZA 937604B ZA 937604 A ZA937604 A ZA 937604A ZA 937604 A ZA937604 A ZA 937604A ZA 937604 B ZA937604 B ZA 937604B
- Authority
- ZA
- South Africa
- Prior art keywords
- indolin
- tetracyclic
- disubstituted
- tri
- treatment
- Prior art date
Links
- 208000010877 cognitive disease Diseases 0.000 title 1
- 150000005623 oxindoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96052292A | 1992-10-13 | 1992-10-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA937604B true ZA937604B (en) | 1995-04-13 |
Family
ID=25503278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA937604A ZA937604B (en) | 1992-10-13 | 1993-10-13 | 3,3-disubstituted tri and tetracyclic indolin-2-ones useful for the treatment of cognitive disorders |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0664810A1 (xx) |
| JP (1) | JPH08502293A (xx) |
| AU (1) | AU6242294A (xx) |
| CA (1) | CA2146000A1 (xx) |
| IL (1) | IL107251A0 (xx) |
| MX (1) | MX9306337A (xx) |
| WO (1) | WO1994009009A1 (xx) |
| ZA (1) | ZA937604B (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601856B2 (en) | 2006-07-27 | 2009-10-13 | Wyeth | Benzofurans as potassium ion channel modulators |
| CN112624972A (zh) * | 2019-09-24 | 2021-04-09 | 中国人民解放军军事科学院军事医学研究院 | 吖啶酮类化合物及医药用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4760083A (en) * | 1986-04-10 | 1988-07-26 | E. I. Dupont De Nemours & Company | 3,3-disubstituted indolines |
| US5173489A (en) * | 1986-04-10 | 1992-12-22 | The Dupont Merck Pharmaceutical Co. | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers |
| US5278045A (en) * | 1990-02-28 | 1994-01-11 | Du Pont Merck Pharmaceutical Company | Method and compositions to screen compounds for enhancement of the cholinergic, dopaminergic and serotonergic function |
-
1993
- 1993-10-12 JP JP6510082A patent/JPH08502293A/ja active Pending
- 1993-10-12 WO PCT/US1993/009476 patent/WO1994009009A1/en not_active Ceased
- 1993-10-12 CA CA002146000A patent/CA2146000A1/en not_active Abandoned
- 1993-10-12 IL IL107251A patent/IL107251A0/xx unknown
- 1993-10-12 EP EP93923238A patent/EP0664810A1/en not_active Withdrawn
- 1993-10-12 MX MX9306337A patent/MX9306337A/es unknown
- 1993-10-12 AU AU62422/94A patent/AU6242294A/en not_active Abandoned
- 1993-10-13 ZA ZA937604A patent/ZA937604B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994009009A1 (en) | 1994-04-28 |
| JPH08502293A (ja) | 1996-03-12 |
| AU6242294A (en) | 1994-05-09 |
| IL107251A0 (en) | 1994-01-25 |
| EP0664810A1 (en) | 1995-08-02 |
| MX9306337A (es) | 1995-01-31 |
| CA2146000A1 (en) | 1994-04-28 |
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