[go: up one dir, main page]

ZA935943B - New formulations - Google Patents

New formulations

Info

Publication number
ZA935943B
ZA935943B ZA935943A ZA935943A ZA935943B ZA 935943 B ZA935943 B ZA 935943B ZA 935943 A ZA935943 A ZA 935943A ZA 935943 A ZA935943 A ZA 935943A ZA 935943 B ZA935943 B ZA 935943B
Authority
ZA
South Africa
Prior art keywords
new formulations
carrier
inhalation
formulations
new
Prior art date
Application number
ZA935943A
Other languages
English (en)
Inventor
Gordon Thomas Simpkin
Roy Trunley
Ann-Marie Leighton
Original Assignee
Rhone Poulenc Rorer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Ltd filed Critical Rhone Poulenc Rorer Ltd
Publication of ZA935943B publication Critical patent/ZA935943B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA935943A 1992-08-14 1993-08-13 New formulations ZA935943B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9217312A GB2269992A (en) 1992-08-14 1992-08-14 Powder inhalation formulations

Publications (1)

Publication Number Publication Date
ZA935943B true ZA935943B (en) 1994-06-09

Family

ID=10720370

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA935943A ZA935943B (en) 1992-08-14 1993-08-13 New formulations

Country Status (16)

Country Link
US (1) US5908639A (xx)
EP (1) EP0654991B1 (xx)
JP (1) JP3787573B2 (xx)
AT (1) ATE154237T1 (xx)
AU (1) AU678379B2 (xx)
CA (1) CA2142126C (xx)
DE (1) DE69311556T2 (xx)
DK (1) DK0654991T3 (xx)
ES (1) ES2106362T3 (xx)
GB (1) GB2269992A (xx)
GR (1) GR3024468T3 (xx)
IL (1) IL106665A (xx)
MX (1) MX9304975A (xx)
NZ (1) NZ254945A (xx)
WO (1) WO1994004133A1 (xx)
ZA (1) ZA935943B (xx)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9322014D0 (en) 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9501841D0 (en) * 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US5612053A (en) * 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
GB9515182D0 (en) 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
US6017963A (en) * 1995-11-14 2000-01-25 Euro-Celtique, S.A. Formulation for intranasal administration
US20020052310A1 (en) 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
FR2756739B1 (fr) * 1996-12-05 2000-04-28 Astra Ab Nouvelle formulation de budesonide
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
JP2001514663A (ja) 1997-03-12 2001-09-11 エスモンド，ロバート ダブリュー． アルツハイマー病を処置または予防するための方法
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6565885B1 (en) * 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US6191154B1 (en) 1998-11-27 2001-02-20 Case Western Reserve University Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AU7685200A (en) 1999-10-12 2001-04-23 Kaken Pharmaceutical Co., Ltd. Powdery inhalational preparations and process for producing the same
CN1188111C (zh) * 1999-10-29 2005-02-09 耐科塔医药公司 分散性得到改进的干粉组合物
WO2001056581A1 (en) * 2000-02-04 2001-08-09 Kissei Pharmaceutical Co., Ltd. Powdered preparation for inhalation and powder inhalant containing the same packed
AU2001234005B2 (en) 2000-02-28 2006-01-19 Pharmakodex Limited Improvements in or relating to the delivery of oral drugs
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
DK1296651T3 (da) * 2000-06-27 2008-02-11 Vectura Ltd Fremgangsmåde til fremstilling af partikler til anvendelse i et farmaceutisk præparat
EP1296651B2 (en) 2000-06-27 2019-07-17 Vectura Limited Method of making particles for use in a pharmaceutical composition
EP1337239B2 (en) * 2000-11-30 2015-11-25 Vectura Limited Particles for use in a pharmaceutical composition
DK1337240T4 (en) 2000-11-30 2015-01-05 Vectura Ltd A process for the preparation of particles for use in a pharmaceutical composition
EP1345629A2 (en) 2000-12-29 2003-09-24 Advanced Inhalation Research, Inc. Particles for inhalation having sustained release properties
WO2003020197A1 (en) 2001-09-05 2003-03-13 Vectura Limited Improvements in or relating to the delivery of oral drugs
CA2465675C (en) 2001-11-20 2008-06-10 Advanced Inhalation Research, Inc. Improved particulate compositions for pulmonary delivery
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
JP2005527508A (ja) 2002-03-07 2005-09-15 ヴェクトゥラ　リミテッド 経口デリバリー用急速溶融多粒子製剤
AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
US7638138B2 (en) 2003-02-21 2009-12-29 Translational Research, Ltd. Compositions for nasal administration of pharmaceuticals
MXPA05010379A (es) 2003-03-27 2006-05-31 Bioactis Ltd Aparato para administrar una medicina en polvo en la cavidad intranasal.
ITMI20040795A1 (it) * 2004-04-23 2004-07-23 Eratech S R L Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa
US8673360B2 (en) 2004-08-10 2014-03-18 Shin Nippon Biomedical Laboratories, Ltd. Compositions that enable rapid-acting and highly absorptive intranasal administration
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
EP1657278A1 (en) 2004-11-12 2006-05-17 SOLVAY (Société Anonyme) Coated particles of calcium carbonate having a high specific surface
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
US20070172430A1 (en) * 2006-01-20 2007-07-26 Nastech Pharmaceutical Company Inc. Dry powder compositions for rna influenza therapeutics
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
JP5415769B2 (ja) 2006-12-26 2014-02-12 株式会社新日本科学 経鼻投与用製剤
CN103252007B (zh) 2008-06-13 2016-06-22 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
MX2011000410A (es) * 2008-07-18 2011-03-24 Prosonix Ltd Proceso para mejorar la cristalinidad de particulas de fluticasona.
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
ES2739352T3 (es) 2009-02-26 2020-01-30 Glaxo Group Ltd Formulaciones farmacéuticas que comprenden 4-{(1R)-2-[(6-{2-[(2,6-diclorobencil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroximetil)fenol
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
US9101539B2 (en) 2009-05-15 2015-08-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
GB2472327B (en) 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
CN105451716A (zh) 2013-07-18 2016-03-30 曼金德公司 热稳定性干粉药物组合物和方法
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
US20230233635A1 (en) 2020-05-26 2023-07-27 Rhodes Technologies Cannabinoid compositions and dosage forms for intranasal or inhalational delivery
JP7606825B2 (ja) * 2020-06-15 2024-12-26 東和薬品株式会社 エソメプラゾール顆粒ならびにその製造方法および用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581225A (en) * 1984-04-25 1986-04-08 Eli Lilly And Company Sustained release intranasal formulation and method of use thereof
US4916230A (en) * 1984-07-02 1990-04-10 Merck & Co., Inc. Process for preparing novel N-(acyloxy-alkoxy)carbonyl derivatives useful as bioreversible prodrug moieties for primary and secondary amine functions in drugs
EP0309519B1 (en) * 1987-04-09 1992-07-08 FISONS plc Pharmaceutical compositions containing pentamidine
US5039699A (en) * 1989-03-27 1991-08-13 Lederle (Japan), Ltd. Anti-peptic ulcer agent
JPH05963A (ja) * 1990-04-13 1993-01-08 Toray Ind Inc ポリペプチド類組成物
GB9020544D0 (en) * 1990-09-20 1990-10-31 Sandoz Ltd Improvements in or relating to organic compounds
IE71647B1 (en) * 1991-01-28 1997-02-26 Rhone Poulenc Rorer Ltd Benzamide derivatives

Also Published As

Publication number Publication date
DE69311556D1 (de) 1997-07-17
NZ254945A (en) 1996-06-25
GB2269992A (en) 1994-03-02
GR3024468T3 (en) 1997-11-28
CA2142126C (en) 2007-01-09
AU678379B2 (en) 1997-05-29
MX9304975A (es) 1994-05-31
IL106665A0 (en) 1993-12-08
JPH08500109A (ja) 1996-01-09
JP3787573B2 (ja) 2006-06-21
ATE154237T1 (de) 1997-06-15
WO1994004133A1 (en) 1994-03-03
GB9217312D0 (en) 1992-09-30
US5908639A (en) 1999-06-01
DK0654991T3 (da) 1997-12-29
EP0654991A1 (en) 1995-05-31
DE69311556T2 (de) 1997-12-04
CA2142126A1 (en) 1994-03-03
AU4725693A (en) 1994-03-15
ES2106362T3 (es) 1997-11-01
IL106665A (en) 1998-02-22
EP0654991B1 (en) 1997-06-11

Similar Documents

Publication Publication Date Title
GB9217312D0 (en) New formulations
TW286273B (xx)
MY131774A (en) Coated pesticidal agents, processes for their preparation and compositions containing them
HUT76900A (en) Dry powder inhalator medicament carrier
NZ238739A (en) Aerosol formulations comprising a powdered drug, a hydrofluorocarbon propellant and a perfluoroalkylsulphonamidoalkylphosphate surface-active agent
EP0681491A4 (en) INTRAPULMONARY CONTRIBUTION OF HORMONES.
AU645342B2 (en) Antimicrobial peptides and an antimicrobial agent
AU584900B2 (en) Formulating and delivery system for emulsion blasting agents
MXPA97002401A (es) Agente antiinflamatorio para uso externo.
CZ20011581A3 (cs) Systém pro podávání bioaktivní sloučeniny inhalací
CA2004598A1 (en) Medicinal aerosol formulations
CA2277824A1 (en) Dosage composition for nasal delivery and method of use of the same
ZA971324B (en) Powdered medication inhaler.
IL111533A0 (en) Quinoxalinedione derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same
HU904007D0 (en) Medical preparations providing regulated active agent discharge and processes for the preparation thereof
IL97931A0 (en) Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
AU631334B2 (en) 2-substituted n,n'-ditrimethoxybenzoyl piperazines, and therapeutic compositions containing them
AU2721995A (en) Coated pesticidal agents, processing for their preparation and compositions containing them
AU7467994A (en) Novel polysaccharide and radioprotective agent containing the same as active ingredient
GB9312982D0 (en) Active agent delivery systems
AU1092095A (en) Intra-uterine ring for the release of an active agent, such as a hormone, and an introducer
HUT75711A (en) The use of dimeticone as a transport and carrier system and/or drug delivery system, and pharmaceutical compositions containing dimeticone
SG34313A1 (en) Tape carrying active agent-containing fine powder
BG101119A (en) Analgesic composition
IL94658A0 (en) 1,5-diazabicyclodiones and pharmaceutical compositions containing them