ZA93436B - Benzopyran derivatives - Google Patents
Benzopyran derivativesInfo
- Publication number
- ZA93436B ZA93436B ZA93436A ZA93436A ZA93436B ZA 93436 B ZA93436 B ZA 93436B ZA 93436 A ZA93436 A ZA 93436A ZA 93436 A ZA93436 A ZA 93436A ZA 93436 B ZA93436 B ZA 93436B
- Authority
- ZA
- South Africa
- Prior art keywords
- represent
- hydroxy
- benzopyran derivatives
- hydrogen
- formula
- Prior art date
Links
- 150000001562 benzopyrans Chemical class 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001088 anti-asthma Effects 0.000 abstract 1
- 230000003556 anti-epileptic effect Effects 0.000 abstract 1
- 239000000924 antiasthmatic agent Substances 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- -1 hydroxy, substituted amino Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1081992 | 1992-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA93436B true ZA93436B (en) | 1993-08-25 |
Family
ID=11760967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA93436A ZA93436B (en) | 1992-01-24 | 1993-01-21 | Benzopyran derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5646308A (fr) |
| EP (1) | EP0632033B1 (fr) |
| JP (1) | JP3260458B2 (fr) |
| KR (1) | KR100217167B1 (fr) |
| CN (1) | CN1036918C (fr) |
| AT (1) | ATE178601T1 (fr) |
| AU (1) | AU3367393A (fr) |
| CA (1) | CA2128603A1 (fr) |
| DE (1) | DE69324354T2 (fr) |
| DK (1) | DK0632033T3 (fr) |
| ES (1) | ES2132217T3 (fr) |
| GR (1) | GR3030581T3 (fr) |
| SG (1) | SG52734A1 (fr) |
| WO (1) | WO1993015068A1 (fr) |
| ZA (1) | ZA93436B (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428031A (en) * | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
| EP0702952B1 (fr) * | 1993-04-23 | 1999-12-08 | Chugai Seiyaku Kabushiki Kaisha | Derives du benzopyranne |
| JP2649610B2 (ja) * | 1993-11-10 | 1997-09-03 | 日本たばこ産業株式会社 | クロマン誘導体及びその医薬用途 |
| FI970668L (fi) * | 1994-08-18 | 1997-02-17 | Merck & Co Ltd | 2,3-dihydro-1-(2,2,2-trifluorietyyli)-2-okso-5-fenyyli-1H-1,4-bentsodiatsepiinejä |
| US5631251A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | 5-cyclopropyl-1,4 benzodiazepine-2-ones |
| US5691331A (en) * | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
| US5700797A (en) * | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
| US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
| ATE235472T1 (de) * | 1995-06-07 | 2003-04-15 | Merck & Co Inc | N-(2-oxo-2,3,4,5-tetrahydro-1h-1,5-benzodiazepi - 3-yl)-3-amide |
| AU3867997A (en) * | 1996-08-27 | 1998-03-19 | Shionogi & Co., Ltd. | Chromene-3-carboxylate derivatives |
| FR2756284B1 (fr) * | 1996-11-26 | 2000-04-28 | Adir | Nouveaux derives du benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| TW533073B (en) * | 1997-03-03 | 2003-05-21 | Chugai Pharmaceutical Co Ltd | Therapeutic agents for peripheral vascular disease |
| WO1999007411A1 (fr) * | 1997-08-08 | 1999-02-18 | Chugai Seiyaku Kabushiki Kaisha | Remedes contre les complications du diabete |
| WO2000018754A1 (fr) * | 1998-09-30 | 2000-04-06 | Chugai Seiyaku Kabushiki Kaisha | Procedes de preparation de derives de benzopyranne 4-substitue |
| CZ20013076A3 (cs) * | 2000-08-29 | 2002-04-17 | Kuraray Co., Ltd. | Způsob výroby chromankarboxylové kyseliny |
| KR100602191B1 (ko) * | 2004-03-10 | 2006-07-19 | 한국화학연구원 | 5-라이폭시게네이즈 저해활성을 가지는2,2'-이중치환-3,4-디하이드로-7,8-이중치환-6-알킬아미노벤조피란 유도체 |
| NZ550441A (en) * | 2004-05-05 | 2009-07-31 | Hoffmann La Roche | Arylsulfonyl benzodioxanes useful for modulating the 5-HT6 receptor, the 5-HT2A receptor or both |
| EP1737847B1 (fr) | 2004-07-30 | 2008-06-04 | Torrent Pharmaceuticals Ltd | Nebivolol et ses sels pharmaceutiquement acceptables, procede de preparation et compositions pharmaceutiques de nebivolol |
| BRPI0515830A (pt) | 2004-12-21 | 2008-08-05 | F Hoffmann La Roche | derivados de cromano e usos dos mesmos no tratamento de distúrbios do sistema nervoso central |
| KR100889185B1 (ko) * | 2004-12-21 | 2009-03-16 | 에프. 호프만-라 로슈 아게 | 테트랄린 및 인단 유도체 및 5-ｈｔ 길항제로서의 이의용도 |
| DK1831159T3 (da) * | 2004-12-21 | 2010-03-22 | Hoffmann La Roche | Tetralin og indanderivater samt anvendelser deraf |
| BRPI0515835A (pt) * | 2004-12-21 | 2008-08-12 | Hoffmann La Roche | derivados de tetralina e de indano e seus usos |
| AU2005318596B2 (en) * | 2004-12-21 | 2010-12-23 | F. Hoffmann-La Roche Ag | Chroman derivatives and their use as 5-HT receptor ligands |
| KR100704009B1 (ko) * | 2005-08-30 | 2007-04-04 | 한국화학연구원 | 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(ｎ-메틸치환술폰아미도)메틸-2ｈ-1-벤조피란 유도체 |
| ATE499355T1 (de) * | 2005-11-03 | 2011-03-15 | Hoffmann La Roche | Arylsulfonylchromane als 5-ht6-inhibitoren |
| WO2007147763A1 (fr) * | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Dérivés arylsulfonylnaphtalène et leurs utilisations |
| KR101064001B1 (ko) * | 2006-06-20 | 2011-09-08 | 에프. 호프만-라 로슈 아게 | 아릴설폰아미딜 테트랄린 유도체 및 이의 용도 |
| CA2653758A1 (fr) * | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Derives tetraline et indane et leurs utilisations |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH619701A5 (fr) * | 1975-08-07 | 1980-10-15 | Bayer Ag | |
| JPS57167981A (en) * | 1981-04-08 | 1982-10-16 | Kowa Co | Benzopyran derivative |
| GB8911280D0 (en) * | 1989-05-17 | 1989-07-05 | Beecham Group Plc | Novel compounds |
| WO1992002514A1 (fr) * | 1990-07-27 | 1992-02-20 | Chugai Seiyaku Kabushiki Kaisha | Nouveau derive de benzopyrane |
-
1993
- 1993-01-21 ZA ZA93436A patent/ZA93436B/xx unknown
- 1993-01-22 JP JP00942193A patent/JP3260458B2/ja not_active Expired - Fee Related
- 1993-01-22 CN CN93102056A patent/CN1036918C/zh not_active Expired - Fee Related
- 1993-01-25 AU AU33673/93A patent/AU3367393A/en not_active Abandoned
- 1993-01-25 WO PCT/JP1993/000086 patent/WO1993015068A1/fr not_active Ceased
- 1993-01-25 DE DE69324354T patent/DE69324354T2/de not_active Expired - Fee Related
- 1993-01-25 KR KR1019940702541A patent/KR100217167B1/ko not_active Expired - Fee Related
- 1993-01-25 DK DK93902526T patent/DK0632033T3/da active
- 1993-01-25 US US08/256,580 patent/US5646308A/en not_active Expired - Fee Related
- 1993-01-25 SG SG1996008501A patent/SG52734A1/en unknown
- 1993-01-25 EP EP93902526A patent/EP0632033B1/fr not_active Expired - Lifetime
- 1993-01-25 AT AT93902526T patent/ATE178601T1/de not_active IP Right Cessation
- 1993-01-25 CA CA002128603A patent/CA2128603A1/fr not_active Abandoned
- 1993-01-25 ES ES93902526T patent/ES2132217T3/es not_active Expired - Lifetime
-
1999
- 1999-06-22 GR GR990401664T patent/GR3030581T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1036918C (zh) | 1998-01-07 |
| DK0632033T3 (da) | 1999-10-18 |
| KR100217167B1 (ko) | 1999-09-01 |
| JP3260458B2 (ja) | 2002-02-25 |
| EP0632033A4 (fr) | 1995-02-01 |
| AU3367393A (en) | 1993-09-01 |
| JPH05294954A (ja) | 1993-11-09 |
| ATE178601T1 (de) | 1999-04-15 |
| EP0632033A1 (fr) | 1995-01-04 |
| US5646308A (en) | 1997-07-08 |
| WO1993015068A1 (fr) | 1993-08-05 |
| CA2128603A1 (fr) | 1993-08-05 |
| EP0632033B1 (fr) | 1999-04-07 |
| DE69324354T2 (de) | 1999-11-25 |
| KR950700277A (ko) | 1995-01-16 |
| DE69324354D1 (de) | 1999-05-12 |
| SG52734A1 (en) | 1998-09-28 |
| GR3030581T3 (en) | 1999-10-29 |
| CN1077954A (zh) | 1993-11-03 |
| ES2132217T3 (es) | 1999-08-16 |
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