ZA918025B - Acetylenes disubstituted with a heteroaromatic group and a 2-substituted cromanyl,thiocromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity - Google Patents

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted cromanyl,thiocromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

Info

Publication number: ZA918025B
Authority: ZA; South Africa
Prior art keywords: group; thiocromanyl; cromanyl; retinoid; substituted
Prior art date: 1990-10-09

Application number

ZA918025A

Other languages

English (en)

Inventor

Roshantha A S Chandraratna

A S Chandraratna Roshantha

Original Assignee

Allergan Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-09

Filing date

1991-10-08

Publication date

1992-06-24

1991-10-08 Application filed by Allergan Inc filed Critical Allergan Inc

1992-06-24 Publication of ZA918025B publication Critical patent/ZA918025B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ZA918025A 1990-10-09 1991-10-08 Acetylenes disubstituted with a heteroaromatic group and a 2-substituted cromanyl,thiocromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity ZA918025B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US59512890A	1990-10-09	1990-10-09

Publications (1)

Publication Number	Publication Date
ZA918025B true ZA918025B (en)	1992-06-24

Family

ID=24381853

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA918025A ZA918025B (en)	1990-10-09	1991-10-08	Acetylenes disubstituted with a heteroaromatic group and a 2-substituted cromanyl,thiocromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

Country Status (13)

Country	Link
EP (1)	EP0555235A4 (xx)
JP (1)	JPH06501684A (xx)
AU (1)	AU657100B2 (xx)
CA (1)	CA2091763A1 (xx)
FI (1)	FI931624A7 (xx)
HU (1)	HUT63412A (xx)
IE (1)	IE913568A1 (xx)
IL (1)	IL99618A0 (xx)
NZ (1)	NZ240059A (xx)
PL (1)	PL168075B1 (xx)
PT (1)	PT99189A (xx)
WO (1)	WO1992006092A1 (xx)
ZA (1)	ZA918025B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5602130A (en) *	1987-03-20	1997-02-11	Allergan	Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US7452911B2 (en)	2002-10-31	2008-11-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
CN107176945B (zh) *	2016-03-11	2021-06-08	中国科学院上海有机化学研究所	一种视黄酸类化合物、其制备方法、中间体及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3816466A (en) *	1971-12-22	1974-06-11	Warner Lambert Co	Flavanoid ring systems
US3868379A (en) *	1972-04-28	1975-02-25	Warner Lambert Co	Heterocyclic amides of 4-hydroxy-2H-1-benzothiopyran-3-carboxylic acid 1,1-dioxide
CA1305480C (en) *	1987-03-20	1992-07-21	Roshantha A.S. Chandraratna	Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US5045551A (en) *	1989-09-19	1991-09-03	Allergan, Inc.	Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5023341A (en) *	1989-09-19	1991-06-11	Allergan, Inc.	Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity

1991
- 1991-09-24 WO PCT/US1991/006900 patent/WO1992006092A1/en not_active Ceased
- 1991-09-24 HU HU931031A patent/HUT63412A/hu unknown
- 1991-09-24 EP EP19910917319 patent/EP0555235A4/en not_active Withdrawn
- 1991-09-24 FI FI931624A patent/FI931624A7/fi not_active Application Discontinuation
- 1991-09-24 PL PL91299062A patent/PL168075B1/pl not_active IP Right Cessation
- 1991-09-24 JP JP3515926A patent/JPH06501684A/ja active Pending
- 1991-09-24 AU AU86149/91A patent/AU657100B2/en not_active Ceased
- 1991-09-24 CA CA002091763A patent/CA2091763A1/en not_active Abandoned
- 1991-10-01 NZ NZ240059A patent/NZ240059A/xx unknown
- 1991-10-01 IL IL99618A patent/IL99618A0/xx unknown
- 1991-10-08 ZA ZA918025A patent/ZA918025B/xx unknown
- 1991-10-09 PT PT99189A patent/PT99189A/pt not_active Application Discontinuation
- 1991-10-16 IE IE356891A patent/IE913568A1/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
PT99189A (pt)	1992-09-30
EP0555235A4 (en)	1993-11-10
NZ240059A (en)	1993-10-26
FI931624L (fi)	1993-04-08
CA2091763A1 (en)	1992-04-10
IL99618A0 (en)	1992-08-18
PL168075B1 (pl)	1995-12-30
EP0555235A1 (en)	1993-08-18
JPH06501684A (ja)	1994-02-24
FI931624A0 (fi)	1993-04-08
WO1992006092A1 (en)	1992-04-16
FI931624A7 (fi)	1993-04-08
HUT63412A (en)	1993-08-30
IE913568A1 (en)	1992-04-22
AU8614991A (en)	1992-04-28
HU9301031D0 (en)	1993-07-28
AU657100B2 (en)	1995-03-02

Similar Documents

Publication	Publication Date	Title
EP0423358A4 (en)	1992-05-06	Postostatin and related compound thereof, or their salts
NZ234679A (en)	1991-11-26	4-phosphonomethyl-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane n-oxide and salts thereof
IL101530A0 (en)	1992-12-30	3,4,n-trisubstituted-4,5-dihydro-1h-pyrazole-1-carboxamides and their use as insecticides
HU913050D0 (en)	1992-01-28	1,3-benzoxasine derivatives, production and application thereof
FI894629A7 (fi)	1990-03-31	Uusia 3,4-diaminokinoliini- ja -pyridiiniyhdisteitä
IL101774A0 (en)	1992-12-30	Microencapsulated agriculturally active agents,and their production
FI923189A7 (fi)	1992-07-10	2-substituoituja 4,5-difenyyliimidatsoleja
MX9203459A (es)	1992-08-01	Nuevos derivados de 2'-halometilideno, 2'-etenilideno y 2'-etinilcitidina, uridina y guanosina.
BR8903908A (pt)	1990-03-27	Artigo de reduco de atrito
IT1214648B (it)	1990-01-18	8 alfa-acilamminoergoline,loro preparazione e loro impiego come medicamenti
DE68909253D1 (de)	1993-10-28	1-Aminomethyl-1,2,3,4-tetrahydronaphthaline und -indane.
FI931459L (fi)	1993-10-02	Sammansaettningar med 1-klor-2,2,2-trifluoretyldifluor-metyleter
IL99617A0 (en)	1992-08-18	Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl,thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
GB8908587D0 (en)	1989-06-01	New 2-substituted n,n'-ditrimethoxybenzoyl piperazines
FI923458A7 (fi)	1992-07-31	4,5-sykloalkano-3-bentsatsepin-7-olijohdannaiset ja niiden käyttö
ZA918025B (en)	1992-06-24	Acetylenes disubstituted with a heteroaromatic group and a 2-substituted cromanyl,thiocromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
IT8520903A0 (it)	1985-05-27	Derivato chinolin-lattaminico ad attivita' antibatterica ed inibitrice delle b-lattamasi.
EP0425680A4 (en)	1992-07-08	New vitamin b 12? derivative, production thereof, and application thereof
IT8621999A0 (it)	1986-10-14	Derivati pirido-benzotiazinici adattivita' antibatterica ed a lunga durata di azione.
IL76074A0 (en)	1985-12-31	Substituted acylhydrazones,their production and their use as bactericides and/or fungicides
NO923489L (no)	1993-03-10	1,4-dihydroksypyridiner med paf-antagonistisk aktivitet
AU627355C (en)	1995-08-10	Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4- tetrahydroquinolinyl group having retinoid-like activity
DE58904664D1 (de)	1993-07-15	Durchschreibesatz, bestehend aus unbeschrifteten und/oder beschrifteten blaettern und/oder formularblaettern.
ITMI912652A1 (it)	1993-04-04	Medicamento ad attivita' antielastasica.
NO931344L (no)	1993-06-04	Acetylener disubstituert med en fenylgruppe og en 2-substituert kromanyl-, tiokromanyl- eller 1,2,3,4 - tetrahydrokinolinylgruppe med retinoidlignende aktivitet