ZA91490B - Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity - Google Patents
Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activityInfo
- Publication number
- ZA91490B ZA91490B ZA91490A ZA91490A ZA91490B ZA 91490 B ZA91490 B ZA 91490B ZA 91490 A ZA91490 A ZA 91490A ZA 91490 A ZA91490 A ZA 91490A ZA 91490 B ZA91490 B ZA 91490B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyridylphenyl
- derivatives
- nitrogen heterocycle
- inflammatory activity
- substituted carbinols
- Prior art date
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/469,854 US5049570A (en) | 1990-01-23 | 1990-01-23 | Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA91490B true ZA91490B (en) | 1992-09-30 |
Family
ID=23865295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA91490A ZA91490B (en) | 1990-01-23 | 1991-01-23 | Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5049570A (xx) |
| EP (1) | EP0513149B1 (xx) |
| JP (1) | JP3053428B2 (xx) |
| KR (1) | KR927003575A (xx) |
| AT (1) | ATE131475T1 (xx) |
| AU (1) | AU632905B2 (xx) |
| CA (1) | CA2074723C (xx) |
| DE (1) | DE69115468T2 (xx) |
| GR (1) | GR3019121T3 (xx) |
| IE (1) | IE910207A1 (xx) |
| IL (1) | IL97007A0 (xx) |
| NZ (1) | NZ236850A (xx) |
| WO (1) | WO1991011445A1 (xx) |
| ZA (1) | ZA91490B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ270418A (en) * | 1994-02-07 | 1997-09-22 | Eisai Co Ltd | Polycyclic triazole & imidazole derivatives, antifungal compositions |
| US6265584B1 (en) * | 1998-05-22 | 2001-07-24 | Bristol-Myers Squibb Company | Water soluble prodrugs of azole compounds |
| HRP20100675T1 (hr) | 2003-12-23 | 2011-01-31 | Astex Therapeutics Limited | Derivati pirazola kao modulatori protein kinaze |
| US7880000B2 (en) * | 2004-05-07 | 2011-02-01 | Amgen Inc. | Protein kinase modulators and method of use |
| WO2006136823A1 (en) * | 2005-06-21 | 2006-12-28 | Astex Therapeutics Limited | Heterocyclic containing amines as kinase b inhibitors |
| JP2008546751A (ja) | 2005-06-22 | 2008-12-25 | アステックス・セラピューティクス・リミテッド | 医薬組成物 |
| EP1933832A2 (en) | 2005-06-23 | 2008-06-25 | Astex Therapeutics Limited | Pharmaceutical combinations comprising pyrazole derivatives as protein kinase modulators |
| GB0704932D0 (en) | 2007-03-14 | 2007-04-25 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| TW201609661A (zh) | 2013-12-05 | 2016-03-16 | 拜耳作物科學公司 | Ｎ－環烷基－ｎ－｛［２－（１－經取代環烷基）苯基］亞甲基｝－（硫代）甲醯胺衍生物 |
| WO2015082587A1 (en) | 2013-12-05 | 2015-06-11 | Bayer Cropscience Ag | N-cycloalkyl-n-{[2-(1-substitutedcycloalkyl)phenyl]methylene}-(thio)carboxamide derivatives |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2732750A1 (de) * | 1977-07-20 | 1979-02-08 | Merck Patent Gmbh | Basische thioaether und verfahren zu ihrer herstellung |
| DE2851116A1 (de) * | 1978-11-25 | 1980-06-12 | Bayer Ag | Hydroxyethyl-azole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2920374A1 (de) * | 1979-05-19 | 1980-11-20 | Bayer Ag | Fungizide mittel, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide |
| DE2920375A1 (de) * | 1979-05-19 | 1980-11-20 | Bayer Ag | Fungizide mittel, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide |
| DE3345813A1 (de) * | 1983-12-17 | 1985-06-27 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue 2-(1-imidazolyl)-ethanol-derivate |
| DE3413173A1 (de) * | 1984-04-07 | 1985-10-17 | Bayer Ag, 5090 Leverkusen | (1,2,4-triazol-1-yl)-methyl-carbinole |
| DE3813841A1 (de) * | 1987-06-03 | 1988-12-15 | Bayer Ag | Heterocyclische hydroxyethylazole |
| US4859693A (en) * | 1988-08-10 | 1989-08-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory carbinoloimidazoles |
-
1990
- 1990-01-23 US US07/469,854 patent/US5049570A/en not_active Expired - Lifetime
-
1991
- 1991-01-09 EP EP91903786A patent/EP0513149B1/en not_active Expired - Lifetime
- 1991-01-09 DE DE69115468T patent/DE69115468T2/de not_active Expired - Fee Related
- 1991-01-09 WO PCT/US1991/000022 patent/WO1991011445A1/en not_active Ceased
- 1991-01-09 KR KR1019920701744A patent/KR927003575A/ko not_active Withdrawn
- 1991-01-09 AU AU72228/91A patent/AU632905B2/en not_active Ceased
- 1991-01-09 JP JP3503531A patent/JP3053428B2/ja not_active Expired - Lifetime
- 1991-01-09 AT AT91903786T patent/ATE131475T1/de active
- 1991-01-09 CA CA002074723A patent/CA2074723C/en not_active Expired - Fee Related
- 1991-01-22 NZ NZ236850A patent/NZ236850A/en unknown
- 1991-01-22 IE IE020791A patent/IE910207A1/en unknown
- 1991-01-23 IL IL97007A patent/IL97007A0/xx unknown
- 1991-01-23 ZA ZA91490A patent/ZA91490B/xx unknown
-
1996
- 1996-02-28 GR GR960400545T patent/GR3019121T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP3053428B2 (ja) | 2000-06-19 |
| AU7222891A (en) | 1991-08-21 |
| AU632905B2 (en) | 1993-01-14 |
| HK1006840A1 (en) | 1999-03-19 |
| WO1991011445A1 (en) | 1991-08-08 |
| NZ236850A (en) | 1994-01-26 |
| IL97007A0 (en) | 1992-03-29 |
| EP0513149B1 (en) | 1995-12-13 |
| EP0513149A1 (en) | 1992-11-19 |
| DE69115468D1 (de) | 1996-01-25 |
| US5049570A (en) | 1991-09-17 |
| CA2074723A1 (en) | 1991-07-24 |
| CA2074723C (en) | 2001-10-30 |
| KR927003575A (ko) | 1992-12-18 |
| GR3019121T3 (en) | 1996-05-31 |
| IE910207A1 (en) | 1991-07-31 |
| ATE131475T1 (de) | 1995-12-15 |
| DE69115468T2 (de) | 1996-05-23 |
| JPH05507904A (ja) | 1993-11-11 |
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