ZA914747B - Piperidyl-substituted indoles - Google Patents

Piperidyl-substituted indoles

Info

Publication number: ZA914747B
Authority: ZA; South Africa
Prior art keywords: piperidyl; substituted indoles; methyl; mammals; mammal
Prior art date: 1990-06-22

Application number

ZA914747A

Other languages

English (en)

Inventor

Jens Perregaard

Perregaard Jens

Brenda Costall

Costall Brenda

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-22

Filing date

1991-06-20

Publication date

1992-03-25

1991-06-20 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

1992-03-25 Publication of ZA914747B publication Critical patent/ZA914747B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Anesthesiology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

ZA914747A 1990-06-22 1991-06-20 Piperidyl-substituted indoles ZA914747B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK152090A DK152090D0 (da)	1990-06-22	1990-06-22	Piperidylsubstituerede indolderivater
SG19795A SG19795G (en)	1990-06-22	1995-02-07	Piperidyl-substituted indoles

Publications (1)

Publication Number	Publication Date
ZA914747B true ZA914747B (en)	1992-03-25

Family

ID=26065861

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA914747A ZA914747B (en)	1990-06-22	1991-06-20	Piperidyl-substituted indoles

Country Status (17)

Country	Link
US (1)	US5439922A (xx)
EP (1)	EP0533824B1 (xx)
JP (1)	JP3332232B2 (xx)
AT (1)	ATE113838T1 (xx)
AU (1)	AU650464B2 (xx)
CA (1)	CA2085987C (xx)
DE (1)	DE69105135T2 (xx)
DK (2)	DK152090D0 (xx)
FI (1)	FI925801A0 (xx)
HK (1)	HK51395A (xx)
IE (1)	IE65421B1 (xx)
IL (1)	IL98574A (xx)
NO (1)	NO924949L (xx)
NZ (1)	NZ238655A (xx)
SG (1)	SG19795G (xx)
WO (1)	WO1992000070A1 (xx)
ZA (1)	ZA914747B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5643784A (en) *	1990-12-04	1997-07-01	H, Lundbeck A/S	Indan derivatives
NZ243065A (en) *	1991-06-13	1995-07-26	Lundbeck & Co As H	Piperidine derivatives and pharmaceutical compositions
DK55192D0 (da) *	1992-04-28	1992-04-28	Lundbeck & Co As H	1-piperazino-1,2-dihydroindenderivater
DK78692D0 (da) *	1992-06-12	1992-06-12	Lundbeck & Co As H	Dimere piperidin- og piperazinderivater
DK148392D0 (da) *	1992-12-09	1992-12-09	Lundbeck & Co As H	Heterocykliske forbindelser
DK148292D0 (da) *	1992-12-09	1992-12-09	Lundbeck & Co As H	Forbindelser
US5631017A (en) *	1993-03-26	1997-05-20	Beth Israel Deaconess Medical Center, Inc.	Topical application of buspirone for treatment of pathological conditions associated with immune responses
US5484788A (en) *	1993-03-26	1996-01-16	Beth Israel Hospital Association	Buspirone as a systemic immunosuppressant
DK123493D0 (da) *	1993-11-01	1993-11-01	Lundbeck & Co As H	Compounds
DK139593D0 (da) *	1993-12-16	1993-12-16	Lundbeck & Co As H	Compounds
DE19500689A1 (de) *	1995-01-12	1996-07-18	Merck Patent Gmbh	Indolpiperidin-Derivate
US5637314A (en) *	1995-06-07	1997-06-10	Beth Israel Deaconess Medical Center, Inc.	Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
GB9523583D0 (en) *	1995-11-17	1996-01-17	Merck Sharp & Dohme	Therapeutic agents
DE19707628A1 (de) *	1997-02-26	1998-08-27	Merck Patent Gmbh	Oxazolidinone
US6489341B1 (en)	1999-06-02	2002-12-03	Sepracor Inc.	Methods for the treatment of neuroleptic and related disorders using sertindole derivatives
US20070212412A1 (en) *	2005-09-08	2007-09-13	H. Lundbeck A/S	Stable solid formulation of sertindole
TW200821296A (en) *	2006-06-01	2008-05-16	Lundbeck & Co As H	Use of sertindole for the preventive treatment of suicidal behaviour

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2258843B1 (xx) *	1974-01-30	1977-09-09	Roussel Uclaf
US4208417A (en) *	1978-06-29	1980-06-17	Pharmindustrie	Indole derivatives and their use as anxiolytics
IE58370B1 (en) *	1985-04-10	1993-09-08	Lundbeck & Co As H	Indole derivatives
IE61488B1 (en) *	1987-08-13	1994-11-02	Glaxo Group Ltd	Indole derivatives
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
DK158590D0 (da) *	1990-07-02	1990-07-02	Lundbeck & Co As H	Indolderivater

1990
- 1990-06-22 DK DK152090A patent/DK152090D0/da not_active Application Discontinuation
1991
- 1991-06-20 IE IE213791A patent/IE65421B1/en not_active IP Right Cessation
- 1991-06-20 IL IL9857491A patent/IL98574A/en not_active IP Right Cessation
- 1991-06-20 ZA ZA914747A patent/ZA914747B/xx unknown
- 1991-06-21 NZ NZ238655A patent/NZ238655A/en not_active IP Right Cessation
- 1991-06-21 DK DK91912147.5T patent/DK0533824T3/da active
- 1991-06-21 JP JP51105091A patent/JP3332232B2/ja not_active Expired - Fee Related
- 1991-06-21 AU AU80684/91A patent/AU650464B2/en not_active Ceased
- 1991-06-21 DE DE69105135T patent/DE69105135T2/de not_active Expired - Fee Related
- 1991-06-21 CA CA002085987A patent/CA2085987C/en not_active Expired - Fee Related
- 1991-06-21 AT AT91912147T patent/ATE113838T1/de not_active IP Right Cessation
- 1991-06-21 EP EP91912147A patent/EP0533824B1/en not_active Expired - Lifetime
- 1991-06-21 FI FI925801A patent/FI925801A0/fi not_active Application Discontinuation
- 1991-06-21 WO PCT/DK1991/000168 patent/WO1992000070A1/en not_active Ceased
1992
- 1992-12-17 US US07/999,482 patent/US5439922A/en not_active Expired - Lifetime
- 1992-12-21 NO NO92924949A patent/NO924949L/no unknown
1995
- 1995-02-07 SG SG19795A patent/SG19795G/en unknown
- 1995-04-06 HK HK51395A patent/HK51395A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL98574A (en)	1995-11-27
NO924949D0 (no)	1992-12-21
CA2085987C (en)	2000-08-22
US5439922A (en)	1995-08-08
FI925801L (fi)	1992-12-21
ATE113838T1 (de)	1994-11-15
EP0533824A1 (en)	1993-03-31
CA2085987A1 (en)	1991-12-23
IE912137A1 (en)	1992-01-01
NO924949L (no)	1993-02-19
IE65421B1 (en)	1995-10-18
DE69105135T2 (de)	1995-03-23
SG19795G (en)	1995-08-18
DK152090D0 (da)	1990-06-22
EP0533824B1 (en)	1994-11-09
AU650464B2 (en)	1994-06-23
IL98574A0 (en)	1992-07-15
DK0533824T3 (da)	1995-05-01
AU8068491A (en)	1992-01-23
HK51395A (en)	1995-04-13
JPH05509080A (ja)	1993-12-16
JP3332232B2 (ja)	2002-10-07
FI925801A7 (fi)	1992-12-21
DE69105135D1 (de)	1994-12-15
NZ238655A (en)	1993-11-25
WO1992000070A1 (en)	1992-01-09
FI925801A0 (fi)	1992-12-21

Publication	Publication Date	Title
SG19795G (en)	1995-08-18	Piperidyl-substituted indoles
IL116122A0 (en)	1996-01-31	Intermediates to heterocyclic-cyclic amine derivatives
ZA948026B (en)	1996-04-15	Methods for inhibiting smooth muscle cell proliferation and restinosis
YU97292A (sh)	1995-10-24	N-fenilalanil i n-fenilglicil derivati dipeptida l-azetidin-2-karboksilne kiseline
NO821494L (no)	1982-11-09	Terapeutisk nyttige 1-alkyl-2-aminotetralinderivater
DE3268225D1 (de)	1986-02-13	9-(2-(3-indolyl)ethyl)-1-oxa-4,9-diazaspiro(5.5)undecan-3-ones
DK0533000T3 (da)	1997-10-13	Fremgangsmåde til fremstilling af 1,2,3,4-tetrahydro-3-isoquinolinderivater
JPS52156862A (en)	1977-12-27	Novel indoleacetic acid ester derivatives
GR82222B (xx)	1984-12-13
YU140391A (sh)	1994-06-10	6-supstituisani-heksahidrobenz (cd)-indoli
TW225989B (xx)	1994-07-01
DK601888A (da)	1989-05-01	Anvendelse af 2-pyrimidinyl-1-piperazinderivater
YU140491A (sh)	1994-01-20	6-supstituisani-tetrahidrobenz(c,d) indoli
PL246418A1 (en)	1985-07-02	Process for preparing n-/3-trifluoromethylphenyl/-n'-propargylpiperazine
SE8302452D0 (sv)	1983-04-29	Method for treatment of senile dementia
EP0116255A3 (en)	1985-11-06	Treatment of migraine with n-alkyl-piperidinyl benzoate derivatives
PT78931B (en)	1986-09-08	Process for the preparation of 2-formylamino)-n-(1h-tetrazol-5-yl)benzamide and method for the administration thereof
TR199701185A2 (xx)	1998-05-21	Sefalosporin piridinyum t�revleri.
ATE50564T1 (de)	1990-03-15	Heterocyclische verbindungen.
FI921298A7 (fi)	1992-03-25	Menetelmä lääkeaineena käyttökelpoisen 5-(6-imidatso/1,2-a/pyridyyli)pyridiini-johdannaisen valmistamiseksi
FI962714L (fi)	1996-07-01	Menetelmä terapeuttisesti käyttökelpoisten naftyridiinijohdannaisten valmistamiseksi
ES8405403A1 (es)	1984-06-01	Procedimiento para la obtencion de 1,4-dihidropiridinas
JPS53130635A (en)	1978-11-14	Novel phenyl acetic acid ester derivatives