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ZA908641B - (n-phthalimidoalkyl)piperidines - Google Patents

(n-phthalimidoalkyl)piperidines

Info

Publication number
ZA908641B
ZA908641B ZA908641A ZA908641A ZA908641B ZA 908641 B ZA908641 B ZA 908641B ZA 908641 A ZA908641 A ZA 908641A ZA 908641 A ZA908641 A ZA 908641A ZA 908641 B ZA908641 B ZA 908641B
Authority
ZA
South Africa
Prior art keywords
phthalimidoalkyl
piperidines
Prior art date
Application number
ZA908641A
Other languages
English (en)
Inventor
Engelbert Ciganek
Ciganek Engelbert
Sang William Tam
William Tam Sang
Ann Sorrentino Wright
Sorrentino Wright Ann
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of ZA908641B publication Critical patent/ZA908641B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA908641A 1989-10-27 1990-10-29 (n-phthalimidoalkyl)piperidines ZA908641B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42809789A 1989-10-27 1989-10-27

Publications (1)

Publication Number Publication Date
ZA908641B true ZA908641B (en) 1992-06-24

Family

ID=23697544

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA908641A ZA908641B (en) 1989-10-27 1990-10-29 (n-phthalimidoalkyl)piperidines

Country Status (5)

Country Link
EP (1) EP0497843A4 (fr)
KR (1) KR927002347A (fr)
CA (1) CA2069318A1 (fr)
WO (1) WO1991006297A1 (fr)
ZA (1) ZA908641B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356906A (en) * 1989-10-27 1994-10-18 The Du Pont Merck Pharmaceutical Company (N-phthalimidoalkyl) piperidines useful as treatments for psychosis
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
US5162341A (en) * 1991-02-22 1992-11-10 Du Pont Merck Pharmaceutical Company Use of sigma receptor antagonists for treatment of amphetamine abuse
US5180729A (en) * 1991-02-22 1993-01-19 Du Pont Merck Pharmaceutical Company Use of sigma receptor antagonists for treatment of cocaine abuse
ATE201677T1 (de) * 1992-04-23 2001-06-15 Merrell Pharma Inc 4-imidomethyl-1-(2'-phenyl-2-oxoethyl)-piperidi e als serotonin-5ht2-antagonisten, ihre herstellung und therapeutische anwendung
FR2713639B1 (fr) * 1993-12-09 1996-08-30 Irj Nouveaux dérivés de 2-arylalkényl-azacycloalkanes ligands aux récepteurs sigma, leur procédé de préparation et leur application en thérapeutique.
GB9416571D0 (en) * 1994-08-16 1994-10-12 Battelle Memorial Institute Novel alkylamino derivatives as sigma 2 selective ligands
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
EP1024799A1 (fr) * 1997-10-24 2000-08-09 Warner-Lambert Company Methode de traitement de dyskinesies liees a une maladie ou provoquees par l'absorption de medicaments
DE60129210T2 (de) 2000-02-29 2008-03-20 Mitsubishi Pharma Corp. Zyklische amid-derivate
US20040077605A1 (en) 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (fr) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Composés de succinimide hétérocyclique fondu et leurs analogies, modulateurs de la fonction de récepteur d'hormone nucléaire
WO2002046156A2 (fr) * 2000-12-06 2002-06-13 Sepracor, Inc. Piperidines 4,4-disubstituees leurs procedes d'utilisation
EP1467979B1 (fr) 2001-12-19 2008-08-13 Bristol-Myers Squibb Company Composes heterocycliques condenses et leurs substances analogues, modulant la fonction du recepteur hormonal nucleaire
TWI263640B (en) * 2001-12-19 2006-10-11 Bristol Myers Squibb Co Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (fr) 2005-10-31 2007-05-10 Braincells, Inc. Modulation de la neurogenese dont la mediation est assuree par recepteur gaba
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
EP4494704A3 (fr) * 2010-07-20 2025-04-23 Minerva Neurosciences, Inc. Utilisation de dérivés d'amide cyclique pour traiter des troubles du sommeil
US20130274290A1 (en) * 2010-07-20 2013-10-17 Cyrenaic Pharmaceuticals, Inc. Methods of use of cyclic amide derivatives to treat sigma receptor mediated disorders
US9458130B2 (en) 2014-12-02 2016-10-04 Minerva Neurosciences, Inc. Compositions and methods for treating schizophrenia
AU2018290287B2 (en) 2017-06-21 2024-06-13 Minerva Neurosciences, Inc. Gastro-resistant controlled release oral dosage forms
WO2020041504A1 (fr) 2018-08-21 2020-02-27 Minerva Neurosciences, Inc. Utilisation de rolupéridone pour traiter des symptômes et des troubles négatifs, augmenter la neuroplasticité et favoriser la neuroprotection
US11919860B1 (en) 2023-10-06 2024-03-05 King Faisal University 1-2(-(substituted phenyl)-2-oxoethyl)-4-(isopropoxycarbonyl)pyridin-1-ium bromides as anti-tubercular agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425578A (en) * 1972-10-21 1976-02-18 Wyeth John & Brother Ltd Piperidine derivatives
SE7907121L (sv) * 1979-08-27 1981-02-28 Astra Laekemedel Ab Ftalimidinderivat
US4495194A (en) * 1982-11-12 1985-01-22 Mead Johnson & Company Antihypertensive isoindole derivatives
NZ216720A (en) * 1985-07-08 1990-09-26 Bristol Myers Co Diazinylpiperidine derivatives and pharmaceutical compositions
DE3717561A1 (de) * 1987-05-25 1988-12-08 Thomae Gmbh Dr K Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
AU593194B2 (en) * 1986-09-26 1990-02-01 Sumitomo Pharmaceuticals Company, Limited Imide derivatives ,and their production and use
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi

Also Published As

Publication number Publication date
EP0497843A4 (en) 1992-09-23
EP0497843A1 (fr) 1992-08-12
WO1991006297A1 (fr) 1991-05-16
KR927002347A (ko) 1992-09-03
CA2069318A1 (fr) 1991-04-28

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