ZA907976B - Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof - Google Patents
Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereofInfo
- Publication number
- ZA907976B ZA907976B ZA907976A ZA907976A ZA907976B ZA 907976 B ZA907976 B ZA 907976B ZA 907976 A ZA907976 A ZA 907976A ZA 907976 A ZA907976 A ZA 907976A ZA 907976 B ZA907976 B ZA 907976B
- Authority
- ZA
- South Africa
- Prior art keywords
- novel
- processes
- preparation
- sulfone derivatives
- cephalosporin sulfone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41807589A | 1989-10-06 | 1989-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA907976B true ZA907976B (en) | 1991-09-25 |
Family
ID=23656604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA907976A ZA907976B (en) | 1989-10-06 | 1990-10-05 | Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5264430A (xx) |
| EP (1) | EP0494914B1 (xx) |
| JP (1) | JPH05503290A (xx) |
| KR (1) | KR927003605A (xx) |
| AT (1) | ATE174919T1 (xx) |
| AU (1) | AU661453B2 (xx) |
| CA (1) | CA2067803A1 (xx) |
| DE (1) | DE69032857T2 (xx) |
| FI (1) | FI921507A7 (xx) |
| HU (2) | HUT61769A (xx) |
| NZ (1) | NZ235589A (xx) |
| WO (1) | WO1991004977A1 (xx) |
| ZA (1) | ZA907976B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA907976B (en) * | 1989-10-06 | 1991-09-25 | Synphar Lab Inc | Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof |
| US5264429A (en) * | 1989-10-06 | 1993-11-23 | Synphar Laboratories, Inc. | 2-spirocyclopropyl cephalosporin sulfone derivatives |
| US5258377A (en) * | 1991-04-08 | 1993-11-02 | Taiho Pharmaceutical Co., Ltd. | 2-spirocyclopropyl 4-acylcephems |
| US5439904A (en) * | 1993-12-07 | 1995-08-08 | Synphar Laboratories, Inc. | 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents |
| JPH11511463A (ja) * | 1995-08-31 | 1999-10-05 | スミスクライン・ビーチャム・コーポレイション | インターロイキン変換酵素およびアポプトーシス |
| HRP970713A2 (en) * | 1997-12-30 | 1999-10-31 | Pliva Pharm & Chem Works | 7-bromo- and 7,7 dibromo-cepham and cephem derivatives |
| US7833998B2 (en) * | 2003-08-25 | 2010-11-16 | Revaax Pharmaceuticals, Llc | Oral neurotherapeutic cephalosporin sulfoxide and sulfone-containing compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH563396A5 (xx) * | 1970-06-05 | 1975-06-30 | Ciba Geigy Ag | |
| US4547371A (en) * | 1983-04-18 | 1985-10-15 | Merck & Co., Inc. | Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents |
| EP0124081A3 (en) * | 1983-05-02 | 1986-11-26 | Merck & Co. Inc. | New substituted cephalosporin sulfones as antiinflammatory and antidegenerative agents, pharmaceutical compositions containing the same and processes for making them |
| EP0267723B1 (en) * | 1986-11-12 | 1996-02-07 | Merck & Co. Inc. | New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents |
| GB8808701D0 (en) * | 1988-04-13 | 1988-05-18 | Erba Carlo Spa | Beta-lactam derivatives |
| GB8811388D0 (en) * | 1988-05-13 | 1988-06-15 | Erba Carlo Spa | 1,1-dioxo-cephem-4-carbothiolic acid derivatives |
| ZA907976B (en) * | 1989-10-06 | 1991-09-25 | Synphar Lab Inc | Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof |
-
1990
- 1990-10-05 ZA ZA907976A patent/ZA907976B/xx unknown
- 1990-10-05 AU AU65131/90A patent/AU661453B2/en not_active Ceased
- 1990-10-05 DE DE69032857T patent/DE69032857T2/de not_active Expired - Fee Related
- 1990-10-05 NZ NZ235589A patent/NZ235589A/xx unknown
- 1990-10-05 EP EP90914668A patent/EP0494914B1/en not_active Expired - Lifetime
- 1990-10-05 HU HU9201149A patent/HUT61769A/hu unknown
- 1990-10-05 CA CA002067803A patent/CA2067803A1/en not_active Abandoned
- 1990-10-05 FI FI921507A patent/FI921507A7/fi not_active Application Discontinuation
- 1990-10-05 HU HU9201149A patent/HU213612B/hu not_active IP Right Cessation
- 1990-10-05 AT AT90914668T patent/ATE174919T1/de not_active IP Right Cessation
- 1990-10-05 WO PCT/CA1990/000343 patent/WO1991004977A1/en not_active Ceased
- 1990-10-05 JP JP2513517A patent/JPH05503290A/ja active Pending
- 1990-10-05 KR KR1019920700808A patent/KR927003605A/ko not_active Ceased
-
1991
- 1991-04-08 US US07/685,960 patent/US5264430A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0494914A1 (en) | 1992-07-22 |
| DE69032857T2 (de) | 1999-08-05 |
| ATE174919T1 (de) | 1999-01-15 |
| WO1991004977A1 (en) | 1991-04-18 |
| FI921507L (fi) | 1992-04-06 |
| JPH05503290A (ja) | 1993-06-03 |
| FI921507A0 (fi) | 1992-04-06 |
| FI921507A7 (fi) | 1992-04-06 |
| NZ235589A (en) | 1993-05-26 |
| KR927003605A (ko) | 1992-12-18 |
| HU9201149D0 (en) | 1992-07-28 |
| AU661453B2 (en) | 1995-07-27 |
| CA2067803A1 (en) | 1991-04-07 |
| EP0494914B1 (en) | 1998-12-23 |
| HU213612B (en) | 1997-08-28 |
| US5264430A (en) | 1993-11-23 |
| AU6513190A (en) | 1991-04-28 |
| DE69032857D1 (de) | 1999-02-04 |
| HUT61769A (en) | 1993-03-01 |
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