ZA905686B - Preparation of n-formyl-l-aspartic anhydride - Google Patents
Preparation of n-formyl-l-aspartic anhydrideInfo
- Publication number
- ZA905686B ZA905686B ZA905686A ZA905686A ZA905686B ZA 905686 B ZA905686 B ZA 905686B ZA 905686 A ZA905686 A ZA 905686A ZA 905686 A ZA905686 A ZA 905686A ZA 905686 B ZA905686 B ZA 905686B
- Authority
- ZA
- South Africa
- Prior art keywords
- formyl
- preparation
- aspartic anhydride
- aspartic
- anhydride
- Prior art date
Links
- DFTMVZIUYVECNW-VKHMYHEASA-N n-[(3s)-2,5-dioxooxolan-3-yl]formamide Chemical compound O=CN[C@H]1CC(=O)OC1=O DFTMVZIUYVECNW-VKHMYHEASA-N 0.000 title abstract 2
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 3
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 2
- 235000019253 formic acid Nutrition 0.000 abstract 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Natural products OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- CKLJMWTZIZZHCS-UWTATZPHSA-N L-Aspartic acid Natural products OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 abstract 1
- 229960005261 aspartic acid Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/66—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA905686A ZA905686B (en) | 1988-02-12 | 1990-07-19 | Preparation of n-formyl-l-aspartic anhydride |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15626888A | 1988-02-12 | 1988-02-12 | |
| ZA905686A ZA905686B (en) | 1988-02-12 | 1990-07-19 | Preparation of n-formyl-l-aspartic anhydride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA905686B true ZA905686B (en) | 1991-07-31 |
Family
ID=22558839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA905686A ZA905686B (en) | 1988-02-12 | 1990-07-19 | Preparation of n-formyl-l-aspartic anhydride |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0466959B1 (xx) |
| JP (1) | JP2611047B2 (xx) |
| KR (1) | KR0185410B1 (xx) |
| CN (1) | CN1058784A (xx) |
| AT (1) | ATE133168T1 (xx) |
| AU (1) | AU649623B2 (xx) |
| BR (1) | BR9007647A (xx) |
| DE (1) | DE69024952T2 (xx) |
| DK (1) | DK0466959T3 (xx) |
| ES (1) | ES2081877T3 (xx) |
| GR (1) | GR3018712T3 (xx) |
| HU (1) | HU209489B (xx) |
| WO (1) | WO1992000949A1 (xx) |
| ZA (1) | ZA905686B (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU648291B2 (en) * | 1988-02-12 | 1994-04-21 | Nutrasweet Company, The | A one-pot process for the preparation of alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride |
| CN102206246A (zh) * | 2011-04-18 | 2011-10-05 | 吴江 | 水相合成N-甲酰-α-L-天门冬氨酰-L-苯丙氨酸的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3933781A (en) * | 1973-11-05 | 1976-01-20 | Monsanto Company | Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters |
| US4508912A (en) * | 1982-03-30 | 1985-04-02 | Ajinomoto Company, Incorporated | Process for producing N-carbobenzoxy-L-aspartic anhydride |
| IT1152488B (it) * | 1982-08-06 | 1986-12-31 | Pierrel Spa | Procedimento per la preparazione dell'anidride dell'acido n-formil-l-aspartico |
| JPS59175484A (ja) * | 1983-03-25 | 1984-10-04 | Ajinomoto Co Inc | Ｎ−ホルミルアスパラギン酸無水物の製造法 |
| US4670568A (en) * | 1984-12-07 | 1987-06-02 | Ajinomoto Co., Inc. | Process of producing n-formylaspartic anhydride |
| JPS63154669A (ja) * | 1986-12-18 | 1988-06-27 | Mitsui Petrochem Ind Ltd | イミダゾ−ル類の製造工程におけるギ酸の除去方法 |
| JPS62252754A (ja) * | 1986-04-24 | 1987-11-04 | Ajinomoto Co Inc | 新規アミノ酸誘導体および甘味剤組成物 |
| JPH085912B2 (ja) * | 1986-09-04 | 1996-01-24 | 味の素株式会社 | Ｎ−ホルミルアスパルチル−フエニルアラニンまたはそのメチルエステルの製造方法 |
| US4801742A (en) * | 1987-07-17 | 1989-01-31 | W. R. Grace & Co.-Conn. | N-formylation of amino carboxylates with alkyl formates |
| JPH01100163A (ja) * | 1987-10-14 | 1989-04-18 | Mitsui Toatsu Chem Inc | Ｎ−ホルミル−ｌ−アスパラギン酸無水物の製造法 |
-
1990
- 1990-07-11 AU AU61506/90A patent/AU649623B2/en not_active Ceased
- 1990-07-11 KR KR1019910700148A patent/KR0185410B1/ko not_active Expired - Fee Related
- 1990-07-11 WO PCT/US1990/003898 patent/WO1992000949A1/en not_active Ceased
- 1990-07-11 BR BR909007647A patent/BR9007647A/pt not_active Application Discontinuation
- 1990-07-11 JP JP2511285A patent/JP2611047B2/ja not_active Expired - Lifetime
- 1990-07-19 ES ES90113843T patent/ES2081877T3/es not_active Expired - Lifetime
- 1990-07-19 AT AT90113843T patent/ATE133168T1/de not_active IP Right Cessation
- 1990-07-19 EP EP90113843A patent/EP0466959B1/en not_active Expired - Lifetime
- 1990-07-19 DE DE69024952T patent/DE69024952T2/de not_active Expired - Fee Related
- 1990-07-19 ZA ZA905686A patent/ZA905686B/xx unknown
- 1990-07-19 DK DK90113843.8T patent/DK0466959T3/da active
- 1990-07-24 HU HU904595A patent/HU209489B/hu not_active IP Right Cessation
- 1990-08-06 CN CN90106907A patent/CN1058784A/zh active Pending
-
1996
- 1996-01-18 GR GR950403643T patent/GR3018712T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR0185410B1 (ko) | 1999-06-01 |
| HU209489B (en) | 1994-06-28 |
| DE69024952T2 (de) | 1996-05-30 |
| HU904595D0 (en) | 1990-12-28 |
| WO1992000949A1 (en) | 1992-01-23 |
| AU6150690A (en) | 1992-02-04 |
| EP0466959A1 (en) | 1992-01-22 |
| AU649623B2 (en) | 1994-06-02 |
| HUT58046A (en) | 1992-01-28 |
| JP2611047B2 (ja) | 1997-05-21 |
| CN1058784A (zh) | 1992-02-19 |
| DK0466959T3 (da) | 1996-02-12 |
| JPH05500359A (ja) | 1993-01-28 |
| EP0466959B1 (en) | 1996-01-17 |
| GR3018712T3 (en) | 1996-04-30 |
| DE69024952D1 (de) | 1996-02-29 |
| BR9007647A (pt) | 1992-09-15 |
| ES2081877T3 (es) | 1996-03-16 |
| ATE133168T1 (de) | 1996-02-15 |
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