[go: up one dir, main page]

ZA897508B - Novel artemisinin derivatives,processes for their preparation and their use as antiprotozoal agents - Google Patents

Novel artemisinin derivatives,processes for their preparation and their use as antiprotozoal agents

Info

Publication number
ZA897508B
ZA897508B ZA897508A ZA897508A ZA897508B ZA 897508 B ZA897508 B ZA 897508B ZA 897508 A ZA897508 A ZA 897508A ZA 897508 A ZA897508 A ZA 897508A ZA 897508 B ZA897508 B ZA 897508B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
antiprotozoal agents
artemisinin derivatives
novel artemisinin
Prior art date
Application number
ZA897508A
Other languages
English (en)
Inventor
Bindumadhavan Venugopalan
Venugopalan Bindumadhavan
Chintamam Prabhakar Bapat
Prabhakar Bapat Chintamam
Pravin Jayant Karnik
Jayant Karnik Pravin
Bansi Lal
Lal Bansi
Deepak Kumar Chatterjee
Kumar Chatterjee Deepak
Subramani Natrajan Iyer
Natrajan Iyer Subramani
Richard Helmut Rupp
Helmut Rupp Richard
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA897508B publication Critical patent/ZA897508B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA897508A 1988-10-04 1989-10-03 Novel artemisinin derivatives,processes for their preparation and their use as antiprotozoal agents ZA897508B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88116378 1988-10-04

Publications (1)

Publication Number Publication Date
ZA897508B true ZA897508B (en) 1991-06-26

Family

ID=8199419

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897508A ZA897508B (en) 1988-10-04 1989-10-03 Novel artemisinin derivatives,processes for their preparation and their use as antiprotozoal agents

Country Status (9)

Country Link
EP (1) EP0362730A1 (xx)
JP (1) JPH02145586A (xx)
KR (1) KR900006340A (xx)
CN (1) CN1041595A (xx)
AU (1) AU629571B2 (xx)
MA (1) MA21645A1 (xx)
MX (1) MX17808A (xx)
NZ (1) NZ230868A (xx)
ZA (1) ZA897508B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225554A (en) * 1986-12-18 1993-07-06 Sri International Polyoxa tetracyclic compounds
US5225427A (en) * 1988-10-04 1993-07-06 Hoechst Aktiengesellschaft 10-substituted ether derivatives of dihydroartemisinin, process for their preparation and their use as antiprotozoal agents
AU640171B2 (en) * 1989-09-27 1993-08-19 Rhone-Poulenc Rorer S.A. Cyclic peroxyacetal lactone, lactol and ether compounds
TW198722B (xx) * 1990-05-07 1993-01-21 Hoechst Ag
US5225562A (en) * 1990-08-10 1993-07-06 Mcchesney James D Method of preparing (+)-deoxoartemisinin and selected analogues of (+)-deoxoartemisinin
AU659505B2 (en) * 1991-10-14 1995-05-18 University Of Sydney, The Cyclic peroxyacetal compounds
CN1049435C (zh) * 1994-11-09 2000-02-16 中国科学院上海药物研究所 含苯基和杂环基的青蒿素衍生物及其制备方法
CH692321A5 (de) * 1997-11-03 2002-05-15 Mepha Ag Pharmazeutisch wirksame Zusammensetzung, welche eine gegen Malariaparasiten wirksame Substanz enthält.
US6160004A (en) * 1997-12-30 2000-12-12 Hauser, Inc. C-10 carbon-substituted artemisinin-like trioxane compounds having antimalarial, antiproliferative and antitumor activities
EP0974593A1 (en) * 1998-07-14 2000-01-26 The Hong Kong University of Science & Technology Artemisinin derivatives as antiparasitic agents
SK542001A3 (en) * 1998-07-14 2001-08-06 Bayer Ag Antiparasitic artemisinin derivatives (endoperoxides)
EP0974594A1 (en) * 1998-07-14 2000-01-26 The Hong Kong University of Science & Technology Artemisinin derivatives as anti-infective agent
EP0974354A1 (en) * 1998-07-14 2000-01-26 The Hong Kong University of Science & Technology Artemisinin derivatives
IN191696B (xx) * 1999-02-12 2003-12-20 Council Scient Ind Res
AU2002352357A1 (en) * 2001-12-06 2003-06-17 Ufc Limited Trioxane derivatives
ES2243103B1 (es) 2002-11-22 2006-12-01 Felipe Puig Aguilella Procedimiento para el llenado de recipientes flexibles normalmente dispuestos sobre receptaculos rigidos paletizados tipo jaula o semirrigidos, y conjunto de dispositivos para realizar dicho llenado.
CN1900081A (zh) * 2005-07-22 2007-01-24 中国科学院上海药物研究所 水溶性青蒿素衍生物、制法、药物组合物及用途
WO2009033494A1 (en) * 2007-09-10 2009-03-19 Dafra Pharma N.V. 1- or 2-substituted artemisinin derivatives for increasing the in vivo biological activity of biologically active compounds
EP2573089A1 (en) * 2011-09-23 2013-03-27 Spago Imaging AB Novel artmisinin derivatives
CN103664982A (zh) * 2013-12-06 2014-03-26 湖南科源生物制品有限公司 青蒿素类似物及其制备方法
CN103664985B (zh) * 2013-12-12 2015-12-09 华东理工大学 β型羟基青蒿烷基醚的立体选择性制备方法
CN105503898B (zh) * 2015-11-16 2018-04-27 中国人民解放军第三军医大学 一种含氮杂环的青蒿素衍生物及其制备方法
CN110448552B (zh) * 2019-08-23 2023-05-12 西南大学 二氢青蒿素衍生物在制备抗疟药物中的应用
KR102266875B1 (ko) * 2019-12-12 2021-06-18 대한민국 감자 바이러스 y 방제용 화합물
CN118165000A (zh) * 2024-02-20 2024-06-11 江苏左右生物医药股份有限公司 马来酸蒿乙醚胺晶型i及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791135A (en) * 1987-08-20 1988-12-13 The United States Of America As Represented By The Secretary Of The Army Novel antimalarial dihydroartemisinin derivatives

Also Published As

Publication number Publication date
MA21645A1 (fr) 1990-07-01
MX17808A (es) 1994-03-31
AU629571B2 (en) 1992-10-08
JPH02145586A (ja) 1990-06-05
NZ230868A (en) 1992-08-26
KR900006340A (ko) 1990-05-08
EP0362730A1 (en) 1990-04-11
AU4242189A (en) 1990-04-12
CN1041595A (zh) 1990-04-25

Similar Documents

Publication Publication Date Title
ZA897508B (en) Novel artemisinin derivatives,processes for their preparation and their use as antiprotozoal agents
EP0412350A3 (en) Renininhibitors, procedure for their preparation and use as medicaments
IL84522A0 (en) Imidazopyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA899725B (en) N-aryl-azetidinones,their preparation process and their use as elastage inhibitors
EP0187620A3 (en) Pyrrolo-pyrroles, process for their preparation and use
IL83760A (en) 3-pyrazoliomethyl-3- cephem-4-carboxylate derivatives, process for the preparation thereof, and pharmacetuical compositions containing the same
IL84913A0 (en) Alkanesulfonanilide derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
ZA866529B (en) Azolyl-cyclopropyl-ethanol derivatives,processes for their preparation and their use
IL86649A0 (en) 2-guanidino-thiazole derivatives,their preparation and use as intermediates
IL74133A0 (en) Azolyl-aryl-alkanol derivatives,processes for their preparation and their use
IL93339A0 (en) 2,3,23-trihydroxy-urs-12-ene and its derivatives,processes for their preparation and their use
ZA83592B (en) Corynantheine derivatives,processes for their preparation,and their use
PT83801B (en) Process for preparing 6,7,8,9/tetrahydro-10-methylpyrido]1,2-a"indol-9-amines and derivatives thereof
ZA879235B (en) Peridone derivatives,and their preparation and use
ZA856431B (en) 1,6-naphthyridine derivatives,process for the preparation and the use thereof
ZA871756B (en) Arylazolylmethylbenzocycloalkene derivatives,processes for the preparation thereof,and the use thereof
IL80977A0 (en) 1-azolyl-3,3-dimethylbutan-2-one and ol derivatives,their preparation and their use as fungicides
IL91332A0 (en) Mitomycin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA87324B (en) Naphthyridine derivatives,processes for their preparation and their use as herbicides
IL90004A0 (en) 5-fluoromethyl pyrimidine-2-sulfonamides,process for their preparation and composition for their use as herbicides
ZA891183B (en) Novel 16-homo-piperidino-androstane derivatives and processes for their preparation
ZA844618B (en) Tetrahydropyridazinone derivatives,processes for their preparation and their use
GB2213480B (en) Dioxazocine derivatives, their preparation and compositions containing them
ZA902002B (en) 2-halocyclopropylethane derivatives,processes for their preparation and their use as pesticides
EP0344112A3 (en) Substituted bisacyloxynaphthacenes, and process for the preparation of tetrathiotetracenes