ZA817929B - 5alpha-and 5beta-androstane-17beta-carboxylates - Google Patents
5alpha-and 5beta-androstane-17beta-carboxylatesInfo
- Publication number
- ZA817929B ZA817929B ZA817929A ZA817929A ZA817929B ZA 817929 B ZA817929 B ZA 817929B ZA 817929 A ZA817929 A ZA 817929A ZA 817929 A ZA817929 A ZA 817929A ZA 817929 B ZA817929 B ZA 817929B
- Authority
- ZA
- South Africa
- Prior art keywords
- 5beta
- 5alpha
- 17beta
- androstane
- carboxylates
- Prior art date
Links
- PBXJGQQGODZSQR-WQBJWTDHSA-N (5s,8r,9s,10s,13s,14s,17s)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene-17-carboxylic acid Chemical class C1CCC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)C(O)=O)[C@@H]4[C@@H]3CC[C@@H]21 PBXJGQQGODZSQR-WQBJWTDHSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21929380A | 1980-12-22 | 1980-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA817929B true ZA817929B (en) | 1982-10-27 |
Family
ID=22818692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA817929A ZA817929B (en) | 1980-12-22 | 1981-11-16 | 5alpha-and 5beta-androstane-17beta-carboxylates |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS57131000A (en) |
| BE (1) | BE891585A (en) |
| DE (1) | DE3149475A1 (en) |
| FR (1) | FR2496668A1 (en) |
| GB (1) | GB2089808A (en) |
| IT (1) | IT1142142B (en) |
| NL (1) | NL8105455A (en) |
| ZA (1) | ZA817929B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78144A0 (en) * | 1985-04-04 | 1986-07-31 | Draco Ab | Novel androstane-17beta-carboxylic acid esters |
| SE8501693D0 (en) * | 1985-04-04 | 1985-04-04 | Draco Ab | NOVEL 16,17-ACETALSUBSTITUTED ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS |
| EP0245357B1 (en) * | 1985-10-23 | 1991-08-07 | The Upjohn Company | Angiostatic steroids |
| JP5780521B2 (en) | 2008-05-28 | 2015-09-16 | リベラジェン・バイオファーマ・インコーポレイテッドＲｅｖｅｒａＧｅｎ ＢｉｏＰｈａｒｍａ，Ｉｎｃ． | Non-hormonal steroid modulators of NF-κB for treating diseases |
| EP2556083A4 (en) | 2010-04-05 | 2013-12-04 | Validus Biopharma Inc | Non-hormonal steroid modulators of nf- kappa b for treatment of disease |
| US10799514B2 (en) | 2015-06-29 | 2020-10-13 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kappa beta for treatment of disease |
| US11382922B2 (en) | 2019-03-07 | 2022-07-12 | Reveragen Biopharma, Inc. | Aqueous oral pharmaceutical suspension compositions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3828080A (en) * | 1972-01-20 | 1974-08-06 | Glaxo Lab Ltd | Androstane-17beta-carboxylic acids and processes for the preparation thereof |
| FI70904C (en) * | 1980-02-15 | 1986-10-27 | Glaxo Group Ltd | FREQUENCY REFERENCE FOR THERAPEUTIC USE OF THERAPEUTIC ACID 11ETA, 17ALFA-DIHYDROXI-3-OXO- -ANDROST-4-EN-17BETA-THIOCARBOX XYATER |
-
1981
- 1981-11-16 ZA ZA817929A patent/ZA817929B/en unknown
- 1981-12-03 NL NL8105455A patent/NL8105455A/en not_active Application Discontinuation
- 1981-12-14 DE DE19813149475 patent/DE3149475A1/en not_active Withdrawn
- 1981-12-18 IT IT25692/81A patent/IT1142142B/en active
- 1981-12-21 FR FR8123840A patent/FR2496668A1/en active Pending
- 1981-12-22 JP JP56207928A patent/JPS57131000A/en active Pending
- 1981-12-22 GB GB8138530A patent/GB2089808A/en not_active Withdrawn
- 1981-12-22 BE BE0/206909A patent/BE891585A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB2089808A (en) | 1982-06-30 |
| DE3149475A1 (en) | 1982-07-15 |
| JPS57131000A (en) | 1982-08-13 |
| IT8125692A0 (en) | 1981-12-18 |
| BE891585A (en) | 1982-06-22 |
| FR2496668A1 (en) | 1982-06-25 |
| IT1142142B (en) | 1986-10-08 |
| NL8105455A (en) | 1982-07-16 |
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