ZA776497B - 4a-aryl-octahydro-1h-2-pyridines - Google Patents

4a-aryl-octahydro-1h-2-pyridines

Info

Publication number: ZA776497B
Authority: ZA; South Africa
Prior art keywords: octahydro; pyridines; aryl
Prior art date: 1976-11-02

Application number

ZA00776497A

Other languages

English (en)

Inventor

D Zimmerman

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-11-02

Filing date

1977-11-01

Publication date

1979-06-27

1977-11-01 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1979-06-27 Publication of ZA776497B publication Critical patent/ZA776497B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/757—Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)

ZA00776497A 1976-11-02 1977-11-01 4a-aryl-octahydro-1h-2-pyridines ZA776497B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US73795876A	1976-11-02	1976-11-02

Publications (1)

Publication Number	Publication Date
ZA776497B true ZA776497B (en)	1979-06-27

Family

ID=24965981

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA00776497A ZA776497B (en)	1976-11-02	1977-11-01	4a-aryl-octahydro-1h-2-pyridines

Country Status (26)

Country	Link
JP (1)	JPS5356669A (xx)
AR (1)	AR223454A1 (xx)
AT (1)	ATA782177A (xx)
AU (1)	AU513679B2 (xx)
BE (1)	BE860314A (xx)
CA (1)	CA1100136A (xx)
CS (1)	CS211380B2 (xx)
DD (1)	DD133795A5 (xx)
DE (1)	DE2748466A1 (xx)
DK (1)	DK485277A (xx)
ES (3)	ES463784A1 (xx)
FR (1)	FR2369267A1 (xx)
GB (1)	GB1590155A (xx)
GR (1)	GR70053B (xx)
HU (1)	HU176231B (xx)
IE (1)	IE45901B1 (xx)
IL (1)	IL53236A0 (xx)
NL (1)	NL7712053A (xx)
NZ (1)	NZ185539A (xx)
PH (1)	PH12590A (xx)
PL (3)	PL109690B1 (xx)
PT (1)	PT67194B (xx)
RO (3)	RO78300A (xx)
SE (3)	SE7712218L (xx)
SU (3)	SU812174A3 (xx)
ZA (1)	ZA776497B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL117572B1 (en) *	1977-12-27	1981-08-31	Lilly Co Eli	Process for preparing novel derivatives of trans-4a-phenyl-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindine3,4,4a,5,6,7,7a-oktagidro-1h-2-piridina
US4236009A (en) *	1979-06-21	1980-11-25	Eli Lilly And Company	Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines
US4277608A (en) *	1979-06-21	1981-07-07	Eli Lilly And Company	Method of preparing 4a-arylhexahydro-1H-2-pyrindines and 4a-aryloctahydroisoquinolines
ZA9510829B (en) *	1994-12-23	1996-07-03	Smithkline Beecham Corp	3,3-(disubstituted)cyclohexan-1-one monomers and related compounds
WO2011140425A1 (en)	2010-05-06	2011-11-10	Vertex Pharmaceuticals Incorporated	Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
TW201604196A (zh)	2011-02-02	2016-02-01	維泰克斯製藥公司	作為離子通道調節劑之吡咯并吡－螺環哌啶醯胺
MX2013009393A (es)	2011-02-18	2013-08-29	Vertex Pharma	Piperidinamidas cromano-espirociclicas como moduladores de canales de iones.
EP2686325B1 (en)	2011-03-14	2016-12-14	Vertex Pharmaceuticals Incorporated	Morpholine-spirocyclic piperidine amides as modulators of ion channels

1977
- 1977-10-26 PT PT67194A patent/PT67194B/pt unknown
- 1977-10-27 IL IL53236A patent/IL53236A0/xx unknown
- 1977-10-27 CA CA289,687A patent/CA1100136A/en not_active Expired
- 1977-10-27 GB GB44729/77A patent/GB1590155A/en not_active Expired
- 1977-10-27 NZ NZ185539A patent/NZ185539A/xx unknown
- 1977-10-28 FR FR7732776A patent/FR2369267A1/fr active Granted
- 1977-10-28 PH PH20380A patent/PH12590A/en unknown
- 1977-10-28 SE SE7712218A patent/SE7712218L/xx unknown
- 1977-10-28 IE IE2206/77A patent/IE45901B1/en unknown
- 1977-10-28 BE BE1008483A patent/BE860314A/xx unknown
- 1977-10-28 DE DE19772748466 patent/DE2748466A1/de not_active Withdrawn
- 1977-10-29 GR GR54664A patent/GR70053B/el unknown
- 1977-10-31 AR AR269797A patent/AR223454A1/es active
- 1977-11-01 NL NL7712053A patent/NL7712053A/xx not_active Application Discontinuation
- 1977-11-01 AU AU30235/77A patent/AU513679B2/en not_active Expired
- 1977-11-01 DK DK485277A patent/DK485277A/da unknown
- 1977-11-01 ZA ZA00776497A patent/ZA776497B/xx unknown
- 1977-11-01 HU HU77EI768A patent/HU176231B/hu unknown
- 1977-11-02 RO RO7799434A patent/RO78300A/ro unknown
- 1977-11-02 DD DD7700201831A patent/DD133795A5/xx unknown
- 1977-11-02 AT AT0782177A patent/ATA782177A/de not_active Application Discontinuation
- 1977-11-02 RO RO7792007A patent/RO72900A/ro unknown
- 1977-11-02 PL PL1977201885A patent/PL109690B1/pl unknown
- 1977-11-02 JP JP13211177A patent/JPS5356669A/ja active Pending
- 1977-11-02 CS CS777150A patent/CS211380B2/cs unknown
- 1977-11-02 ES ES463784A patent/ES463784A1/es not_active Expired
- 1977-11-02 PL PL1977212226A patent/PL108466B1/pl unknown
- 1977-11-02 PL PL1977212225A patent/PL108610B1/pl unknown
- 1977-11-02 ES ES463783A patent/ES463783A1/es not_active Expired
- 1977-11-02 SU SU772539649A patent/SU812174A3/ru active
- 1977-11-02 RO RO7799435A patent/RO77935A/ro unknown
1978
- 1978-08-01 ES ES472276A patent/ES472276A1/es not_active Expired
- 1978-10-03 SU SU782669395A patent/SU845777A3/ru active
- 1978-10-03 SU SU782669355A patent/SU913941A3/ru active
1981
- 1981-05-18 SE SE8103106A patent/SE8103106L/sv unknown
- 1981-05-18 SE SE8103107A patent/SE8103107L/sv unknown

Also Published As

Publication number	Publication date
SU812174A3 (ru)	1981-03-07
GB1590155A (en)	1981-05-28
HU176231B (en)	1981-01-28
PL108610B1 (en)	1980-04-30
DE2748466A1 (de)	1978-05-03
RO72900A (ro)	1981-11-04
ATA782177A (de)	1981-10-15
ES463783A1 (es)	1979-07-16
DK485277A (da)	1978-05-03
BE860314A (fr)	1978-04-28
PT67194B (en)	1979-03-23
SU913941A3 (en)	1982-03-15
AU513679B2 (en)	1980-12-18
GR70053B (xx)	1982-07-26
SE7712218L (sv)	1978-05-03
IL53236A0 (en)	1977-12-30
FR2369267A1 (fr)	1978-05-26
NZ185539A (en)	1979-12-11
ES463784A1 (es)	1978-06-16
SE8103107L (sv)	1981-05-18
ES472276A1 (es)	1979-10-01
PL201885A1 (pl)	1978-12-04
SU845777A3 (ru)	1981-07-07
IE45901L (en)	1978-05-02
CS211380B2 (en)	1982-02-26
PL109690B1 (en)	1980-06-30
FR2369267B1 (xx)	1980-05-16
RO77935A (ro)	1981-12-25
AU3023577A (en)	1979-05-10
SE8103106L (sv)	1981-05-18
JPS5356669A (en)	1978-05-23
PT67194A (en)	1977-11-01
CA1100136A (en)	1981-04-28
PL108466B1 (en)	1980-04-30
IE45901B1 (en)	1982-12-29
AR223454A1 (es)	1981-08-31
PH12590A (en)	1979-06-27
DD133795A5 (de)	1979-01-24
RO78300A (ro)	1982-04-12
NL7712053A (nl)	1978-05-05

Publication	Publication Date	Title
AU2542577A (en)	1978-11-30	4-amino-4-arylcyclohexanones
AU2384277A (en)	1978-10-05	Triazolo-pyrimidines
GB1542539A (en)	1979-03-21	Bicycle-trailer
CS164777A2 (en)	1987-01-15	Zpusob ziskavani krystalickeho xylitolu farmaceuricke jakosti
GB1522457A (en)	1978-08-23	Benzocycloheptafurans
CS474677A2 (en)	1987-06-11	Obrazovy zesilovac
AU3191677A (en)	1979-06-28	Cyclopentan-1-amine
AU2726877A (en)	1979-02-01	Benzofuranyl-benzimidazoles
AU507260B2 (en)	1980-02-07	N-2-imidazolidinylidene-benzeneamine
AU2451277A (en)	1978-10-26	Isothiazolopyridines
AU2714177A (en)	1979-01-25	Phenoxy-hydroxypropylamines
AU1309176A (en)	1977-10-20	Fire-barriers
IL53236A0 (en)	1977-12-30	4a-aryl octahydro-1h-2-pyrindines
GB1538366A (en)	1979-01-17	Pyridobenzodiazepines
JPS52142856A (en)	1977-11-29	Silter
AU2893177A (en)	1979-03-29	Perhydroindolinols
GB1520699A (en)	1978-08-09	Benzoxazolenes
AU508067B2 (en)	1980-03-06	Electroradiography
AU2493077A (en)	1978-11-09	2-amino-substituted-isothioureido bewzenes
CY1158A (en)	1983-01-28	Arylmalonamido-1-oxadethiacephalosporins
AU2378777A (en)	1978-10-05	Amino - alkoxyalkanes
GB1537670A (en)	1979-01-04	De-tinning
AU3192177A (en)	1979-06-28	2-methoxybenzamides
AU2710877A (en)	1979-01-25	Benzodioxepins
GB1540313A (en)	1979-02-07	Low-loader-waggons