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ZA201703129B - Mutated protoporphyrinogen ix oxidase (ppx) genes - Google Patents

Mutated protoporphyrinogen ix oxidase (ppx) genes

Info

Publication number
ZA201703129B
ZA201703129B ZA2017/03129A ZA201703129A ZA201703129B ZA 201703129 B ZA201703129 B ZA 201703129B ZA 2017/03129 A ZA2017/03129 A ZA 2017/03129A ZA 201703129 A ZA201703129 A ZA 201703129A ZA 201703129 B ZA201703129 B ZA 201703129B
Authority
ZA
South Africa
Prior art keywords
ppx
oxidase
genes
mutated protoporphyrinogen
protoporphyrinogen
Prior art date
Application number
ZA2017/03129A
Inventor
Gregory F W Gocal
Peter R Beetham
Schopke Aura De
Sarah Dumm
James Pearce
Christian Schopke
Keith A Walker
Original Assignee
Cibus Us Llc
Cibus Europe Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cibus Us Llc, Cibus Europe Bv filed Critical Cibus Us Llc
Publication of ZA201703129B publication Critical patent/ZA201703129B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213Targeted insertion of genes into the plant genome by homologous recombination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/001Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y103/00Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/03Oxidoreductases acting on the CH-CH group of donors (1.3) with oxygen as acceptor (1.3.3)
    • C12Y103/03004Protoporphyrinogen oxidase (1.3.3.4)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Catching Or Destruction (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA2017/03129A 2010-08-03 2017-05-05 Mutated protoporphyrinogen ix oxidase (ppx) genes ZA201703129B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37043610P 2010-08-03 2010-08-03

Publications (1)

Publication Number Publication Date
ZA201703129B true ZA201703129B (en) 2021-08-25

Family

ID=45560039

Family Applications (5)

Application Number Title Priority Date Filing Date
ZA2013/01067A ZA201301067B (en) 2010-08-03 2013-02-08 Mutated protoporhyrinogen ix oxidase (ppx) genes
ZA2017/03129A ZA201703129B (en) 2010-08-03 2017-05-05 Mutated protoporphyrinogen ix oxidase (ppx) genes
ZA2019/03183A ZA201903183B (en) 2010-08-03 2019-05-21 Mutated protoporphyrinogen ix oxidase (ppx) genes
ZA2022/05535A ZA202205535B (en) 2010-08-03 2022-05-19 Mutated protoporphyrinogen ix oxidase (ppx) genes
ZA2024/03837A ZA202403837B (en) 2010-08-03 2024-05-17 Mutated protoporphyrinogen ix oxidase (ppx) genes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA2013/01067A ZA201301067B (en) 2010-08-03 2013-02-08 Mutated protoporhyrinogen ix oxidase (ppx) genes

Family Applications After (3)

Application Number Title Priority Date Filing Date
ZA2019/03183A ZA201903183B (en) 2010-08-03 2019-05-21 Mutated protoporphyrinogen ix oxidase (ppx) genes
ZA2022/05535A ZA202205535B (en) 2010-08-03 2022-05-19 Mutated protoporphyrinogen ix oxidase (ppx) genes
ZA2024/03837A ZA202403837B (en) 2010-08-03 2024-05-17 Mutated protoporphyrinogen ix oxidase (ppx) genes

Country Status (21)

Country Link
EP (3) EP2600710B1 (en)
JP (6) JP6058536B2 (en)
KR (1) KR101920503B1 (en)
CN (3) CN103327809B (en)
AU (1) AU2011285830B2 (en)
BR (1) BR112013002543B1 (en)
CA (3) CA2807035C (en)
CL (1) CL2013000341A1 (en)
DK (1) DK2600710T3 (en)
EA (2) EA202090661A1 (en)
ES (1) ES2688285T3 (en)
IL (3) IL294685A (en)
IN (1) IN2013MN00188A (en)
LT (1) LT2600710T (en)
MX (3) MX376540B (en)
NZ (2) NZ607627A (en)
PL (1) PL2600710T3 (en)
SI (1) SI2600710T1 (en)
UA (1) UA112969C2 (en)
WO (1) WO2012018862A2 (en)
ZA (5) ZA201301067B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120122223A1 (en) 2010-08-03 2012-05-17 Cibus Us Llc Mutated protoporphyrinogen ix oxidase (ppx) genes
UA112969C2 (en) * 2010-08-03 2016-11-25 Сібас Юс Ллс PLANT RESISTANT TO ONE OR MORE PPH-INHIBITING HERBICIDES CONTAINING PROTOPORPHYRINOGEN IX OXIDASE (PPX) MUTANT GENE
MY169304A (en) 2010-12-16 2019-03-21 Basf Agro Bv Plants having increased tolerance to herbicides
US10041087B2 (en) 2012-06-19 2018-08-07 BASF Agro B.V. Plants having increased tolerance to herbicides
AR091489A1 (en) * 2012-06-19 2015-02-11 Basf Se PLANTS THAT HAVE A GREATER TOLERANCE TO HERBICIDES INHIBITORS OF PROTOPORFIRINOGENO OXIDASA (PPO)
US9957515B2 (en) 2013-03-15 2018-05-01 Cibus Us Llc Methods and compositions for targeted gene modification
CA3206344A1 (en) * 2013-03-15 2014-09-18 Cibus Us Llc Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
US12331303B2 (en) 2013-03-15 2025-06-17 Cibus Us Llc Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
UA123757C2 (en) 2013-08-12 2021-06-02 Басф Агро Б. В. Plants having increased tolerance to herbicides
CA2920591A1 (en) 2013-08-12 2015-02-19 BASF Agro B.V. Plants having increased tolerance to herbicides
KR102569558B1 (en) * 2014-03-14 2023-08-22 시버스 유에스 엘엘씨 Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
MX389329B (en) 2015-06-17 2025-03-11 Basf Agro Bv PLANTS THAT HAVE A GREATER TOLERANCE TO HERBICIDES.
WO2018202199A1 (en) * 2017-05-05 2018-11-08 Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences Methods for isolating cells without the use of transgenic marker sequences
JP2020518253A (en) * 2017-05-05 2020-06-25 インスティテュート・オブ・ジェネティクス・アンド・ディヴェロプメンタル・バイオロジー、チャイニーズ・アカデミー・オブ・サイエンシズInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences Method for isolating cells without the use of transgenic marker sequences
CN110093325B (en) * 2019-02-27 2020-12-29 华中师范大学 Protoporphyrinogen oxidase mutants from tobacco mitochondria and their encoding genes and applications
CN115247157A (en) * 2021-04-02 2022-10-28 青岛清原化合物有限公司 PPO polypeptide with tolerance to PPO inhibitor herbicides and application thereof
CN118956784A (en) * 2021-04-02 2024-11-15 青岛清原种子科学有限公司 PPO polypeptides tolerant to PPO inhibitor herbicides and their applications
CN115354039A (en) * 2021-05-02 2022-11-18 青岛清原化合物有限公司 Methods and applications for creating new genes in living organisms

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US5569597A (en) 1985-05-13 1996-10-29 Ciba Geigy Corp. Methods of inserting viral DNA into plant material
US5268463A (en) 1986-11-11 1993-12-07 Jefferson Richard A Plant promoter α-glucuronidase gene construct
US5608142A (en) 1986-12-03 1997-03-04 Agracetus, Inc. Insecticidal cotton plants
US5302523A (en) 1989-06-21 1994-04-12 Zeneca Limited Transformation of plant cells
ATE225853T1 (en) 1990-04-12 2002-10-15 Syngenta Participations Ag TISSUE-SPECIFIC PROMOTORS
US5204253A (en) 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5498830A (en) 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
US5399680A (en) 1991-05-22 1995-03-21 The Salk Institute For Biological Studies Rice chitinase promoter
DE4216134A1 (en) 1991-06-20 1992-12-24 Europ Lab Molekularbiolog SYNTHETIC CATALYTIC OLIGONUCLEOTIDE STRUCTURES
US5604121A (en) 1991-08-27 1997-02-18 Agricultural Genetics Company Limited Proteins with insecticidal properties against homopteran insects and their use in plant protection
TW261517B (en) 1991-11-29 1995-11-01 Mitsubishi Shozi Kk
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
IT230274Y1 (en) 1993-06-11 1999-06-02 Silc Spa SHAPED ABSORBENT PANEL FOR INCONTINENCE
DK0733059T3 (en) 1993-12-09 2000-10-16 Univ Jefferson Compounds and Methods for Site-directed Mutations in Eukaryotic Cells
PT679657E (en) 1994-04-27 2003-11-28 Novartis Ag NUCLEOSID AND OLIGONUCLEOTIDES WITH 2'-ETER GROUPS
US5767373A (en) 1994-06-16 1998-06-16 Novartis Finance Corporation Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms
US6808904B2 (en) 1994-06-16 2004-10-26 Syngenta Participations Ag Herbicide-tolerant protox genes produced by DNA shuffling
US5608144A (en) 1994-08-12 1997-03-04 Dna Plant Technology Corp. Plant group 2 promoters and uses thereof
US5780296A (en) 1995-01-17 1998-07-14 Thomas Jefferson University Compositions and methods to promote homologous recombination in eukaryotic cells and organisms
US5659026A (en) 1995-03-24 1997-08-19 Pioneer Hi-Bred International ALS3 promoter
US6084155A (en) 1995-06-06 2000-07-04 Novartis Ag Herbicide-tolerant protoporphyrinogen oxidase ("protox") genes
PL187094B1 (en) * 1996-02-28 2004-05-31 Syngenta Participations Ag Dna molecules capable to encode plant protoporphyrinogen oxidase and mutants thereof being resistant to inhibitors
US20020073443A1 (en) * 1996-02-28 2002-06-13 Heifetz Peter B. Herbicide tolerance achieved through plastid transformation
US5731181A (en) 1996-06-17 1998-03-24 Thomas Jefferson University Chimeric mutational vectors having non-natural nucleotides
US5760012A (en) 1996-05-01 1998-06-02 Thomas Jefferson University Methods and compounds for curing diseases caused by mutations
US5888983A (en) 1996-05-01 1999-03-30 Thomas Jefferson University Method and oligonucleobase compounds for curing diseases caused by mutations
US6072050A (en) 1996-06-11 2000-06-06 Pioneer Hi-Bred International, Inc. Synthetic promoters
CN1268186A (en) 1997-04-30 2000-09-27 明尼苏达大学评议会 i (in vivo) use of recombinagenic oligonucleobases to correct genetic lesions in hepatocytes
US6524613B1 (en) 1997-04-30 2003-02-25 Regents Of The University Of Minnesota Hepatocellular chimeraplasty
JP2001512687A (en) 1997-08-05 2001-08-28 キメラジェン,インコーポレーテッド Use of mixed double-stranded oligonucleotides to generate localized genetic changes in plants
AU741013B2 (en) 1997-09-11 2001-11-22 Nihon Nohyaku Co., Ltd. Novel protoporphyrinogen oxidase tolerant to light-requiring herbicides
PT1019516E (en) 1997-10-07 2004-09-30 Embrapa Pesquisa Agropecuaria PROCESS FOR OBTAINING VEGETABLES (LEGUMINOSAE) TRANSGENIC CONTAINING DNA EXOGENO
US6177611B1 (en) 1998-02-26 2001-01-23 Pioneer Hi-Bred International, Inc. Maize promoters
AU769868B2 (en) 1998-04-10 2004-02-05 Sumitomo Chemical Company, Limited A method for evaluating the ability of a compound to inhibit the protoporphyrinogen oxidase activity
US6004804A (en) 1998-05-12 1999-12-21 Kimeragen, Inc. Non-chimeric mutational vectors
US6010907A (en) 1998-05-12 2000-01-04 Kimeragen, Inc. Eukaryotic use of non-chimeric mutational vectors
US6271360B1 (en) 1999-08-27 2001-08-07 Valigen (Us), Inc. Single-stranded oligodeoxynucleotide mutational vectors
BR0014681A (en) * 1999-10-11 2002-08-20 Process to increase crop yield or biomass using the protoporphyrinogen oxidase gene
AU2001260114A1 (en) 2000-03-14 2001-09-24 Syngenta Participations Ag Protoporphyrinogen oxidase ("protox") genes
US6936467B2 (en) * 2000-03-27 2005-08-30 University Of Delaware Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
US7842856B2 (en) * 2005-08-25 2010-11-30 The Board Of Trustees Of The University Of Illinois Herbicide resistance gene, compositions and methods
CN108342376A (en) * 2007-10-05 2018-07-31 赛布斯欧洲公司 The acetohydroxy acid synthase gene being mutated in Btassica
EP2331694B1 (en) * 2008-07-31 2016-03-02 Anglo Netherlands Grain BV Herbicide resistant sunflower plants
KR20110080154A (en) * 2008-09-26 2011-07-12 바스프아그로케미칼 프로덕츠 비.브이. Herbicide-resistant AHS-mutants and methods of use
UA112969C2 (en) * 2010-08-03 2016-11-25 Сібас Юс Ллс PLANT RESISTANT TO ONE OR MORE PPH-INHIBITING HERBICIDES CONTAINING PROTOPORPHYRINOGEN IX OXIDASE (PPX) MUTANT GENE

Also Published As

Publication number Publication date
EP2600710A4 (en) 2014-01-22
JP6396958B2 (en) 2018-09-26
EP2600710A2 (en) 2013-06-12
DK2600710T3 (en) 2018-10-22
MX2013001299A (en) 2013-10-28
KR101920503B1 (en) 2018-11-20
ZA201903183B (en) 2022-11-30
EP4534659A2 (en) 2025-04-09
JP6058536B2 (en) 2017-01-11
IL224535B (en) 2019-05-30
JP2023183416A (en) 2023-12-27
CA3084764C (en) 2023-10-10
CN103327809A (en) 2013-09-25
IL294685A (en) 2022-09-01
IL266730A (en) 2019-07-31
BR112013002543B1 (en) 2020-10-27
CA2807035C (en) 2020-09-01
JP7354205B2 (en) 2023-10-02
CN113957091A (en) 2022-01-21
JP2025143393A (en) 2025-10-01
JP2022023150A (en) 2022-02-07
BR112013002543A2 (en) 2017-07-04
JP7707250B2 (en) 2025-07-14
EA202090661A1 (en) 2020-09-30
JP2019004899A (en) 2019-01-17
IL266730B (en) 2022-08-01
JP6965219B2 (en) 2021-11-10
JP2016220685A (en) 2016-12-28
IN2013MN00188A (en) 2015-05-29
CA2807035A1 (en) 2012-02-09
CN113957091B (en) 2024-08-16
CA3210405A1 (en) 2012-02-09
NZ607627A (en) 2015-10-30
ZA202205535B (en) 2024-09-25
AU2011285830B2 (en) 2015-09-24
ZA201301067B (en) 2017-08-30
CN107384911B (en) 2021-06-01
CN107384911A (en) 2017-11-24
EA201390034A1 (en) 2013-09-30
JP2013545434A (en) 2013-12-26
KR20130093615A (en) 2013-08-22
LT2600710T (en) 2018-12-10
WO2012018862A3 (en) 2012-05-31
CA3084764A1 (en) 2012-02-09
UA112969C2 (en) 2016-11-25
MX348704B (en) 2017-06-26
CN103327809B (en) 2017-04-26
ES2688285T3 (en) 2018-10-31
PL2600710T3 (en) 2019-02-28
NZ761237A (en) 2024-08-30
EP4534659A3 (en) 2025-08-27
NZ811395A (en) 2025-11-28
MX2020011389A (en) 2020-11-24
AU2011285830A1 (en) 2013-03-21
ZA202403837B (en) 2025-08-27
CL2013000341A1 (en) 2013-12-13
MX376540B (en) 2025-03-07
WO2012018862A2 (en) 2012-02-09
SI2600710T1 (en) 2019-01-31
EP3441469A1 (en) 2019-02-13
EP3441469B1 (en) 2024-11-20
EA035397B1 (en) 2020-06-05
EP2600710B1 (en) 2018-08-01

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