ZA200810703B - Compounds having a potentiating effect on the activity of ethionamide and uses thereof - Google Patents
Compounds having a potentiating effect on the activity of ethionamide and uses thereofInfo
- Publication number
- ZA200810703B ZA200810703B ZA200810703A ZA200810703A ZA200810703B ZA 200810703 B ZA200810703 B ZA 200810703B ZA 200810703 A ZA200810703 A ZA 200810703A ZA 200810703 A ZA200810703 A ZA 200810703A ZA 200810703 B ZA200810703 B ZA 200810703B
- Authority
- ZA
- South Africa
- Prior art keywords
- ethionamide
- activity
- compounds
- potentiating effect
- potentiating
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 title 1
- 229960002001 ethionamide Drugs 0.000 title 1
- 230000003389 potentiating effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0606088A FR2903405B1 (fr) | 2006-07-04 | 2006-07-04 | Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200810703B true ZA200810703B (en) | 2009-10-28 |
Family
ID=37775154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200810703A ZA200810703B (en) | 2006-07-04 | 2008-12-19 | Compounds having a potentiating effect on the activity of ethionamide and uses thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8338599B2 (xx) |
| EP (1) | EP2044064A1 (xx) |
| JP (1) | JP2009541474A (xx) |
| KR (1) | KR20090043506A (xx) |
| CN (1) | CN101516876A (xx) |
| AP (1) | AP2009004747A0 (xx) |
| AU (1) | AU2007271013A1 (xx) |
| BR (1) | BRPI0714225A2 (xx) |
| CA (1) | CA2656502C (xx) |
| EA (1) | EA200970081A1 (xx) |
| FR (1) | FR2903405B1 (xx) |
| WO (1) | WO2008003861A1 (xx) |
| ZA (1) | ZA200810703B (xx) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009080432A2 (en) | 2007-12-21 | 2009-07-02 | Eth Zurich | Composition for treatment of tuberculosis |
| GB0813740D0 (en) * | 2008-07-28 | 2008-09-03 | Angeletti P Ist Richerche Biologica | Therapeutic compounds |
| JP5685247B2 (ja) * | 2009-06-25 | 2015-03-18 | バイオヴァーシス・アーゲーＢｉｏｖｅｒｓｙｓ Ａｇ | 結核を処置するための組成物 |
| GB0916608D0 (en) * | 2009-09-22 | 2009-11-04 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| WO2012040170A2 (en) * | 2010-09-20 | 2012-03-29 | University Of Virginia Patent Foundation | Compositions and methods for treating tuberculosis |
| US8962658B2 (en) | 2011-10-25 | 2015-02-24 | Universite De Droit Et De La Sante De Lille 2 | Fluoralkylcarbonyl-oxadiazoles |
| EP2809668B1 (en) | 2012-02-02 | 2017-04-12 | Actelion Pharmaceuticals Ltd. | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives |
| FR3000064A1 (fr) | 2012-12-21 | 2014-06-27 | Univ Lille Ii Droit & Sante | Composes de type spiroisoxazoline ayant une activite potentialisatrice de l'activite d'un antibiotique-composition et produit pharmaceutiques comprenant de tels composes |
| FR3000065A1 (fr) | 2012-12-21 | 2014-06-27 | Univ Lille Ii Droit & Sante | Composes bicycliques ayant une activite potentialisatrice de l'activite d'un antibiotique actif contre les mycobacteries-composition et produit pharmaceutiques comprenant de tels composes |
| ES2671323T3 (es) | 2013-07-22 | 2018-06-06 | Idorsia Pharmaceuticals Ltd | Derivados 1¿(piperazin¿1¿il)¿2¿([1,2,4]triazol¿1¿il)¿etanona |
| AR099789A1 (es) | 2014-03-24 | 2016-08-17 | Actelion Pharmaceuticals Ltd | Derivados de 8-(piperazin-1-il)-1,2,3,4-tetrahidro-isoquinolina |
| AR103399A1 (es) | 2015-01-15 | 2017-05-10 | Actelion Pharmaceuticals Ltd | Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3 |
| HRP20190024T1 (hr) | 2015-01-15 | 2019-02-22 | Idorsia Pharmaceuticals Ltd | Derivati hidroksialkil-piperazina kao modulatori receptora cxcr3 |
| HRP20211894T1 (hr) * | 2017-08-16 | 2022-08-19 | Glaxosmithkline Intellectual Property Development Limited | Novi spojevi |
| US20200281202A1 (en) * | 2017-09-08 | 2020-09-10 | Pi Industries Ltd. | Novel fungicidal heterocyclic compounds |
| CN108558858A (zh) * | 2018-05-23 | 2018-09-21 | 成都师范学院 | 硝基呋喃类抗结核化合物 |
| WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| CN116438174B (zh) * | 2020-06-23 | 2025-10-31 | 南京艾美斐生物医药科技有限公司 | 化合物及其作为mif抑制剂的用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2275458A1 (fr) * | 1974-06-21 | 1976-01-16 | Aries Robert | Analogues de la rifampicine portant un noyau oxadiazole |
| US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
| WO2001002375A1 (en) * | 1999-07-01 | 2001-01-11 | Chemrx Advanced Technologies, Inc. | Process for synthesizing oxadiazoles |
| US20010049373A1 (en) * | 2000-01-28 | 2001-12-06 | Chalquest Richard R. | Materials and methods for killing nematodes and nematode eggs |
| WO2003093297A2 (en) * | 2002-05-03 | 2003-11-13 | Exelixis, Inc. | Protein kinase modulators and methods of use |
| JP2006502134A (ja) * | 2002-08-09 | 2006-01-19 | アストラゼネカ アクチボラグ | 代謝調節型グルタミン酸受容体において活性を有する化合物 |
| GB0325956D0 (en) * | 2003-11-06 | 2003-12-10 | Addex Pharmaceuticals Sa | Novel compounds |
| JP4958560B2 (ja) * | 2003-12-24 | 2012-06-20 | プロシディオン・リミテッド | Ｇｐｃｒ受容体作動薬としてのヘテロ環誘導体 |
| EP1604989A1 (en) * | 2004-06-08 | 2005-12-14 | Santhera Pharmaceuticals (Deutschland) Aktiengesellschaft | DPP-IV inhibitors |
| AU2005290081B2 (en) * | 2004-08-23 | 2010-12-02 | Merck Sharp & Dohme Corp. | Inhibitors of Akt activity |
| TW200633990A (en) * | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
| TW200635587A (en) * | 2004-12-01 | 2006-10-16 | Kalypsys Inc | Inducible nitric oxide synthase dimerization inhibitors |
| AU2005316826A1 (en) * | 2004-12-15 | 2006-06-22 | Merck Sharp & Dohme Corp. | Inhibitors of Akt activity |
| US8193359B2 (en) * | 2004-12-24 | 2012-06-05 | Prosidion Limited | G-protein coupled receptor agonists |
-
2006
- 2006-07-04 FR FR0606088A patent/FR2903405B1/fr not_active Expired - Fee Related
-
2007
- 2007-07-04 BR BRPI0714225-0A patent/BRPI0714225A2/pt active Search and Examination
- 2007-07-04 US US12/306,333 patent/US8338599B2/en not_active Expired - Fee Related
- 2007-07-04 JP JP2009517335A patent/JP2009541474A/ja active Pending
- 2007-07-04 EP EP07803843A patent/EP2044064A1/fr not_active Withdrawn
- 2007-07-04 WO PCT/FR2007/001138 patent/WO2008003861A1/fr not_active Ceased
- 2007-07-04 EA EA200970081A patent/EA200970081A1/ru unknown
- 2007-07-04 AP AP2009004747A patent/AP2009004747A0/xx unknown
- 2007-07-04 KR KR1020097002316A patent/KR20090043506A/ko not_active Withdrawn
- 2007-07-04 CA CA2656502A patent/CA2656502C/fr not_active Expired - Fee Related
- 2007-07-04 CN CNA2007800326714A patent/CN101516876A/zh active Pending
- 2007-07-04 AU AU2007271013A patent/AU2007271013A1/en not_active Abandoned
-
2008
- 2008-12-19 ZA ZA200810703A patent/ZA200810703B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009541474A (ja) | 2009-11-26 |
| US8338599B2 (en) | 2012-12-25 |
| US20110136823A1 (en) | 2011-06-09 |
| CA2656502C (fr) | 2017-06-13 |
| AP2009004747A0 (en) | 2009-02-28 |
| FR2903405B1 (fr) | 2011-09-09 |
| CN101516876A (zh) | 2009-08-26 |
| WO2008003861A1 (fr) | 2008-01-10 |
| KR20090043506A (ko) | 2009-05-06 |
| AU2007271013A1 (en) | 2008-01-10 |
| EP2044064A1 (fr) | 2009-04-08 |
| FR2903405A1 (fr) | 2008-01-11 |
| BRPI0714225A2 (pt) | 2013-01-29 |
| CA2656502A1 (fr) | 2008-01-10 |
| EA200970081A1 (ru) | 2009-06-30 |
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