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ZA200810460B - Modified beta-lactamase and method for its preparation - Google Patents

Modified beta-lactamase and method for its preparation

Info

Publication number
ZA200810460B
ZA200810460B ZA200810460A ZA200810460A ZA200810460B ZA 200810460 B ZA200810460 B ZA 200810460B ZA 200810460 A ZA200810460 A ZA 200810460A ZA 200810460 A ZA200810460 A ZA 200810460A ZA 200810460 B ZA200810460 B ZA 200810460B
Authority
ZA
South Africa
Prior art keywords
lactamase
preparation
modified beta
beta
modified
Prior art date
Application number
ZA200810460A
Other languages
English (en)
Inventor
Susanna Kaeaeriaeinen
Nina Wickstrand
Pertti Koski
Original Assignee
Ipsat Therapies Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsat Therapies Oy filed Critical Ipsat Therapies Oy
Publication of ZA200810460B publication Critical patent/ZA200810460B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA200810460A 2006-06-21 2008-12-10 Modified beta-lactamase and method for its preparation ZA200810460B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20065431A FI119190B (fi) 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi

Publications (1)

Publication Number Publication Date
ZA200810460B true ZA200810460B (en) 2009-12-30

Family

ID=36651526

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200810460A ZA200810460B (en) 2006-06-21 2008-12-10 Modified beta-lactamase and method for its preparation

Country Status (15)

Country Link
US (1) US7989192B2 (xx)
EP (1) EP2038411B1 (xx)
JP (1) JP5306191B2 (xx)
KR (1) KR101609243B1 (xx)
CN (1) CN101484577A (xx)
AU (1) AU2007262916B2 (xx)
BR (1) BRPI0713726B1 (xx)
CA (1) CA2659691C (xx)
ES (1) ES2452321T3 (xx)
FI (1) FI119190B (xx)
NO (1) NO342006B1 (xx)
NZ (1) NZ573696A (xx)
RU (1) RU2009101795A (xx)
WO (1) WO2007147945A1 (xx)
ZA (1) ZA200810460B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20105572A0 (fi) 2010-05-24 2010-05-24 Prevab R Lcc Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt
NZ604013A (en) * 2010-06-16 2014-10-31 Abbott Lab Comparison of protein samples
US9405884B2 (en) 2010-06-16 2016-08-02 Abbvie Inc. Methods and systems for the analysis of protein samples
EP3156496B1 (fr) * 2011-04-21 2019-04-10 Biomérieux Inc. Procede de detection d'au moins un mecanisme de resistance aux cephalosporines par spectrometrie de masse
US9290754B2 (en) 2014-04-17 2016-03-22 Synthetic Biologics Inc. Beta-lactamases with improved properties for therapy
US11034966B2 (en) 2014-08-28 2021-06-15 Synthetic Biologics, Inc. E. coli-based production of beta-lactamase
KR102467968B1 (ko) 2014-10-08 2022-11-16 신세틱 바이오로직스, 인코퍼레이티드 베타-락타마제 제형 및 이의 용도
FR3027307B1 (fr) 2014-10-16 2016-11-04 Azurrx Sas Molecule proteique hybride apte a inhiber au moins un antibiotique et composition pharmaceutique la comportant
WO2016105498A1 (en) 2014-12-23 2016-06-30 Synthetic Biologics, Inc. Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics
WO2016137993A1 (en) 2015-02-23 2016-09-01 Synthetic Biologics, Inc. Carbapenemases for use with antibiotics for the protection of the intestinal microbiome
KR20170122776A (ko) 2015-03-06 2017-11-06 신세틱 바이오로직스, 인코퍼레이티드 마이크로바이옴 보호를 위한 안전하고 유효한 베타-락타마제 투약
PT3420078T (pt) * 2016-02-23 2022-07-13 Da Volterra Variantes da beta-lactamase
WO2017144495A1 (en) 2016-02-23 2017-08-31 Da Volterra Beta-lactamase variants
KR20210040997A (ko) 2018-08-05 2021-04-14 다 볼떼라 항암제 효능의 개선 방법
CN112689506A (zh) 2018-08-05 2021-04-20 达·沃尔泰拉公司 用于治疗移植物抗宿主疾病的组合物
US20220154156A1 (en) * 2019-03-11 2022-05-19 Regents Of The University Of Minnesota Proteins and methods for disrupting bacterial communication
WO2021137645A1 (ko) * 2019-12-30 2021-07-08 (재)씨젠의료재단 카바페넴 항생제에 대한 내성을 가지는 병원성 균주의 직접 검출 방법
EP4148136A1 (en) 2021-09-08 2023-03-15 Da Volterra An engineered yeast cell for the delivery of antibiotic-inactivating enzymes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI920206A0 (fi) 1992-01-17 1992-01-17 Pekka Untamo Heino Medicinsk anvaendning, medicinskt foerfarande och preparat.
FI112666B (fi) 2001-11-06 2003-12-31 Ipsat Therapies Oy Itiöimätön Bacillus subtilis, sen valmistus ja käyttö
FR2843302B1 (fr) 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs

Also Published As

Publication number Publication date
WO2007147945A1 (en) 2007-12-27
BRPI0713726A2 (pt) 2012-10-30
WO2007147945A8 (en) 2009-07-30
CN101484577A (zh) 2009-07-15
CA2659691A1 (en) 2007-12-27
AU2007262916A1 (en) 2007-12-27
EP2038411A1 (en) 2009-03-25
BRPI0713726B1 (pt) 2023-01-10
AU2007262916B2 (en) 2013-12-05
FI20065431L (fi) 2007-12-22
US7989192B2 (en) 2011-08-02
JP2009540814A (ja) 2009-11-26
EP2038411A4 (en) 2010-04-07
NZ573696A (en) 2011-09-30
EP2038411B1 (en) 2014-02-26
KR101609243B1 (ko) 2016-04-05
CA2659691C (en) 2015-05-19
RU2009101795A (ru) 2010-07-27
JP5306191B2 (ja) 2013-10-02
ES2452321T3 (es) 2014-03-31
NO342006B1 (no) 2018-03-12
NO20090297L (no) 2009-01-19
FI119190B (fi) 2008-08-29
KR20090046787A (ko) 2009-05-11
FI20065431A0 (fi) 2006-06-21
US20090181004A1 (en) 2009-07-16

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