ZA200805786B - Use of CNS penetrating anticancer compounds for the treatment of protozoal diseases - Google Patents
Use of CNS penetrating anticancer compounds for the treatment of protozoal diseasesInfo
- Publication number
- ZA200805786B ZA200805786B ZA200805786A ZA200805786A ZA200805786B ZA 200805786 B ZA200805786 B ZA 200805786B ZA 200805786 A ZA200805786 A ZA 200805786A ZA 200805786 A ZA200805786 A ZA 200805786A ZA 200805786 B ZA200805786 B ZA 200805786B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- anticancer compounds
- protozoal diseases
- cns penetrating
- cns
- Prior art date
Links
- 230000001093 anti-cancer Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000000149 penetrating effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06000654A EP1808173A1 (en) | 2006-01-12 | 2006-01-12 | Use of CNS penetrating anticancer compounds for the treatment of protozan diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200805786B true ZA200805786B (en) | 2009-08-26 |
Family
ID=36061620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200805786A ZA200805786B (en) | 2006-01-12 | 2008-07-02 | Use of CNS penetrating anticancer compounds for the treatment of protozoal diseases |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20110118199A1 (xx) |
| EP (2) | EP1808173A1 (xx) |
| CA (1) | CA2635825A1 (xx) |
| WO (1) | WO2007080116A2 (xx) |
| ZA (1) | ZA200805786B (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201503234SA (en) | 2010-05-03 | 2015-06-29 | Teikoku Pharma Usa Inc | Non-Aqueous Taxane Pro-Emulsion Formulations and Methods of Making and Using the Same |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| CA2928035C (en) | 2012-12-27 | 2024-07-02 | Massachusetts Eye & Ear Infirmary | Treatment of rhinosinusitis with p-glycoprotein inhibitors |
| CN104910069B (zh) * | 2014-12-15 | 2018-03-23 | 北京科技大学 | 氨茴酸类衍生物、其制备方法及其在医药上的用途 |
| JP7085485B2 (ja) | 2016-01-15 | 2022-06-16 | マサチューセッツ アイ アンド イヤー インファーマリー | 分泌型p-糖タンパク質は、慢性鼻副鼻腔炎の非侵襲的バイオマーカーである |
| WO2017214468A1 (en) | 2016-06-09 | 2017-12-14 | Tien Yang Der | Nanodroplet compositions for the efficient delivery of anti-cancer agents |
| CN108659001B (zh) * | 2018-07-16 | 2020-01-31 | 陕西科技大学 | 一种氟哌噻吨衍生物及其制备方法 |
| US12295933B2 (en) | 2019-03-25 | 2025-05-13 | Massachusetts Eye And Ear Infirmary | Methods and compositions to treat and diagnose diseases or pathologies associated with inflammation of the sinuses and nasal cavity |
| EP4574143A1 (en) * | 2023-12-21 | 2025-06-25 | Universität Regensburg | Inhibitors of plasmodia remodeling enzymes |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399151A (en) * | 1980-06-16 | 1983-08-16 | Merrell Dow Pharmaceuticals Inc. | Method of inhibiting the growth of protozoa |
| US5260291A (en) * | 1981-08-24 | 1993-11-09 | Cancer Research Campaign Technology Limited | Tetrazine derivatives |
| US5101072A (en) * | 1989-09-06 | 1992-03-31 | Yale University | Sulfonylhydrazines and their use as antineoplastic agents and as antitrypanosomal agents |
| US5631278A (en) * | 1992-12-02 | 1997-05-20 | Thomas Jefferson University | Methods of killing protozoal parasites |
| FR2707165B1 (fr) * | 1993-07-06 | 1995-08-11 | Rhone Poulenc Rorer Sa | Application des taxoides au traitement de maladies d'origine parasitaire . |
| US6703400B2 (en) * | 2001-02-23 | 2004-03-09 | Schering Corporation | Methods for treating multidrug resistance |
| AP2006003756A0 (en) * | 2004-03-05 | 2006-10-31 | He Regents Of The University O | Anti-parasitic compounds and methods of their use |
| CN1742723A (zh) * | 2004-09-02 | 2006-03-08 | 天津倍方科技发展有限公司 | 含有替莫唑胺-8-羧酸酯的药物组合物以及该类化合物用于制备抗肿瘤药物的用途 |
| CN1752088A (zh) * | 2004-09-22 | 2006-03-29 | 天津市金士力药物研究开发有限公司 | 含有替莫唑胺酯的药用组合物 |
-
2006
- 2006-01-12 EP EP06000654A patent/EP1808173A1/en not_active Withdrawn
-
2007
- 2007-01-11 US US12/160,596 patent/US20110118199A1/en not_active Abandoned
- 2007-01-11 EP EP07702700A patent/EP1971335A2/en not_active Withdrawn
- 2007-01-11 CA CA002635825A patent/CA2635825A1/en not_active Abandoned
- 2007-01-11 WO PCT/EP2007/000224 patent/WO2007080116A2/en not_active Ceased
-
2008
- 2008-07-02 ZA ZA200805786A patent/ZA200805786B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007080116A2 (en) | 2007-07-19 |
| CA2635825A1 (en) | 2007-07-19 |
| EP1971335A2 (en) | 2008-09-24 |
| WO2007080116A3 (en) | 2007-11-29 |
| EP1808173A1 (en) | 2007-07-18 |
| US20110118199A1 (en) | 2011-05-19 |
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