ZA200703307B - Indol derivatives as inhibitors of soluble adenylyl cyclase - Google Patents
Indol derivatives as inhibitors of soluble adenylyl cyclaseInfo
- Publication number
- ZA200703307B ZA200703307B ZA200703307A ZA200703307A ZA200703307B ZA 200703307 B ZA200703307 B ZA 200703307B ZA 200703307 A ZA200703307 A ZA 200703307A ZA 200703307 A ZA200703307 A ZA 200703307A ZA 200703307 B ZA200703307 B ZA 200703307B
- Authority
- ZA
- South Africa
- Prior art keywords
- inhibitors
- adenylyl cyclase
- soluble adenylyl
- indol derivatives
- indol
- Prior art date
Links
- 102100032157 Adenylate cyclase type 10 Human genes 0.000 title 1
- 101000775498 Homo sapiens Adenylate cyclase type 10 Proteins 0.000 title 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004047272A DE102004047272A1 (de) | 2004-09-24 | 2004-09-24 | Inhibitoren der löslichen Adenylatzyklase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200703307B true ZA200703307B (en) | 2009-05-27 |
Family
ID=37600950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200703307A ZA200703307B (en) | 2004-09-24 | 2007-04-23 | Indol derivatives as inhibitors of soluble adenylyl cyclase |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20080004268A1 (xx) |
| EP (1) | EP1802572B1 (xx) |
| JP (1) | JP2008514572A (xx) |
| KR (1) | KR20070054685A (xx) |
| CN (1) | CN101084189A (xx) |
| AR (1) | AR051300A1 (xx) |
| AT (1) | ATE429419T1 (xx) |
| AU (1) | AU2005287481A1 (xx) |
| BR (1) | BRPI0516057A (xx) |
| CA (1) | CA2581492A1 (xx) |
| CR (1) | CR9058A (xx) |
| DE (1) | DE502005007158D1 (xx) |
| EA (1) | EA200700555A1 (xx) |
| GT (1) | GT200500268A (xx) |
| IL (1) | IL181739A0 (xx) |
| MX (1) | MX2007003287A (xx) |
| MY (1) | MY142839A (xx) |
| NO (1) | NO20072078L (xx) |
| PA (1) | PA8646301A1 (xx) |
| PE (1) | PE20060696A1 (xx) |
| SV (1) | SV2006002238A (xx) |
| TW (1) | TW200615260A (xx) |
| UY (1) | UY29141A1 (xx) |
| ZA (1) | ZA200703307B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070225284A1 (en) * | 2006-03-23 | 2007-09-27 | Bernd Buchmann | Inhibitors of soluble adenylate cyclase |
| CN102262159B (zh) | 2010-05-27 | 2014-03-26 | 李建远 | 用于检测生育相关人睾丸和附睾表达305种精子定位蛋白的方法 |
| US10981899B2 (en) | 2016-04-28 | 2021-04-20 | Cornell University | Inhibitors of soluble adenylyl cyclase |
| US11186549B2 (en) | 2017-08-29 | 2021-11-30 | Rutgers, The State University Of New Jersey | Therapeutic indazoles |
| WO2019046465A2 (en) * | 2017-08-29 | 2019-03-07 | Rutgers, The State University Of New Jersey | THERAPEUTIC INDOLES |
| CN108096244B (zh) * | 2018-01-25 | 2020-11-24 | 昆明医科大学 | 1-氢-2-吲哚酮-3-苄基/取代苄基-3-甲酸酯类化合物的用途 |
| EP3851853A1 (en) * | 2020-01-17 | 2021-07-21 | Biotechnologicky Ustav AV CR, v.v.i. | Method for separation of sperm with undamaged intact heads from sperm with damaged heads and somatic cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100720844B1 (ko) * | 1998-07-08 | 2007-05-25 | 사노피-아벤티스 도이칠란트 게엠베하 | 황 치환된 설포닐아미노카복실산 ｎ-아릴아미드, 이의 제조방법, 및 이를 함유하는 약제학적 제제 |
| US7442805B2 (en) * | 2003-09-25 | 2008-10-28 | Wyeth | Substituted sulfonamide-indoles |
| US7417066B2 (en) * | 2005-06-08 | 2008-08-26 | Schering Ag | Inhibitors of soluble adenylate cyclase |
| US20070225284A1 (en) * | 2006-03-23 | 2007-09-27 | Bernd Buchmann | Inhibitors of soluble adenylate cyclase |
-
2005
- 2005-09-23 MY MYPI20054478A patent/MY142839A/en unknown
- 2005-09-23 AT AT05794403T patent/ATE429419T1/de not_active IP Right Cessation
- 2005-09-23 EP EP05794403A patent/EP1802572B1/de not_active Expired - Lifetime
- 2005-09-23 MX MX2007003287A patent/MX2007003287A/es not_active Application Discontinuation
- 2005-09-23 EA EA200700555A patent/EA200700555A1/ru unknown
- 2005-09-23 CN CNA2005800322659A patent/CN101084189A/zh active Pending
- 2005-09-23 KR KR1020077006633A patent/KR20070054685A/ko not_active Withdrawn
- 2005-09-23 JP JP2007532864A patent/JP2008514572A/ja active Pending
- 2005-09-23 DE DE502005007158T patent/DE502005007158D1/de not_active Expired - Fee Related
- 2005-09-23 BR BRPI0516057-0A patent/BRPI0516057A/pt not_active IP Right Cessation
- 2005-09-23 AU AU2005287481A patent/AU2005287481A1/en not_active Abandoned
- 2005-09-23 CA CA002581492A patent/CA2581492A1/en not_active Abandoned
- 2005-09-23 TW TW094133179A patent/TW200615260A/zh unknown
- 2005-09-26 GT GT200500268A patent/GT200500268A/es unknown
- 2005-09-26 AR ARP050104008A patent/AR051300A1/es unknown
- 2005-09-26 PA PA20058646301A patent/PA8646301A1/es unknown
- 2005-09-26 SV SV2005002238A patent/SV2006002238A/es not_active Application Discontinuation
- 2005-09-26 UY UY29141A patent/UY29141A1/es not_active Application Discontinuation
- 2005-09-26 PE PE2005001108A patent/PE20060696A1/es not_active Application Discontinuation
-
2007
- 2007-03-06 IL IL181739A patent/IL181739A0/en unknown
- 2007-04-18 CR CR9058A patent/CR9058A/es not_active Application Discontinuation
- 2007-04-23 ZA ZA200703307A patent/ZA200703307B/xx unknown
- 2007-04-23 NO NO20072078A patent/NO20072078L/no not_active Application Discontinuation
- 2007-08-07 US US11/835,164 patent/US20080004268A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0516057A (pt) | 2008-08-19 |
| EP1802572A1 (de) | 2007-07-04 |
| IL181739A0 (en) | 2007-07-04 |
| KR20070054685A (ko) | 2007-05-29 |
| ATE429419T1 (de) | 2009-05-15 |
| NO20072078L (no) | 2007-05-31 |
| CR9058A (es) | 2007-10-04 |
| PA8646301A1 (es) | 2006-09-08 |
| UY29141A1 (es) | 2006-04-28 |
| EA200700555A1 (ru) | 2007-10-26 |
| MX2007003287A (es) | 2007-10-11 |
| GT200500268A (es) | 2006-10-10 |
| AU2005287481A1 (en) | 2006-03-30 |
| EP1802572B1 (de) | 2009-04-22 |
| US20080004268A1 (en) | 2008-01-03 |
| MY142839A (en) | 2011-01-14 |
| PE20060696A1 (es) | 2006-08-01 |
| DE502005007158D1 (de) | 2009-06-04 |
| TW200615260A (en) | 2006-05-16 |
| CA2581492A1 (en) | 2006-03-30 |
| AR051300A1 (es) | 2007-01-03 |
| CN101084189A (zh) | 2007-12-05 |
| JP2008514572A (ja) | 2008-05-08 |
| SV2006002238A (es) | 2006-06-26 |
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