ZA200700425B - Dihydropteridinone infusion solution having a long shelf life - Google Patents

Dihydropteridinone infusion solution having a long shelf life

Info

Publication number: ZA200700425B
Authority: ZA; South Africa
Prior art keywords: dihydropteridinone; shelf life; infusion solution; long shelf; infusion
Prior art date: 2004-08-14

Application number

ZA200700425A

Other languages

English (en)

Inventor

Mohr Detlef

Veit Claus

Traulsen Fridtjof

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-08-14

Filing date

2007-01-15

Publication date

2008-10-29

2007-01-15 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2008-10-29 Publication of ZA200700425B publication Critical patent/ZA200700425B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Inorganic Chemistry (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Hematology (AREA)
Rheumatology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA200700425A 2004-08-14 2007-01-15 Dihydropteridinone infusion solution having a long shelf life ZA200700425B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP04019363		2004-08-14

Publications (1)

Publication Number	Publication Date
ZA200700425B true ZA200700425B (en)	2008-10-29

Family

ID=34926183

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200700425A ZA200700425B (en)	2004-08-14	2007-01-15	Dihydropteridinone infusion solution having a long shelf life

Country Status (32)

Country	Link
US (3)	US20060035903A1 (xx)
EP (1)	EP1778238B1 (xx)
JP (1)	JP5048491B2 (xx)
KR (1)	KR101235092B1 (xx)
CN (2)	CN101039676A (xx)
AR (1)	AR050918A1 (xx)
AT (1)	ATE528007T1 (xx)
AU (1)	AU2005274339B2 (xx)
BR (1)	BRPI0513997A (xx)
CA (1)	CA2575821C (xx)
CY (1)	CY1112211T1 (xx)
DK (1)	DK1778238T3 (xx)
EA (1)	EA014237B1 (xx)
EC (1)	ECSP077250A (xx)
ES (1)	ES2375980T3 (xx)
HR (1)	HRP20110966T1 (xx)
IL (1)	IL181306A (xx)
ME (1)	ME01264B (xx)
MX (1)	MX2007001855A (xx)
MY (1)	MY147799A (xx)
NO (1)	NO20070984L (xx)
NZ (1)	NZ553815A (xx)
PE (3)	PE20060645A1 (xx)
PL (1)	PL1778238T3 (xx)
PT (1)	PT1778238E (xx)
RS (1)	RS52043B (xx)
SI (1)	SI1778238T1 (xx)
TW (1)	TWI371278B (xx)
UA (1)	UA92470C2 (xx)
UY (1)	UY29060A1 (xx)
WO (1)	WO2006018221A1 (xx)
ZA (1)	ZA200700425B (xx)

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US8546566B2 (en)	2010-10-12	2013-10-01	Boehringer Ingelheim International Gmbh	Process for manufacturing dihydropteridinones and intermediates thereof
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2005
- 2005-08-05 US US11/197,927 patent/US20060035903A1/en not_active Abandoned
- 2005-08-11 PL PL05778137T patent/PL1778238T3/pl unknown
- 2005-08-11 EA EA200700389A patent/EA014237B1/ru not_active IP Right Cessation
- 2005-08-11 HR HR20110966T patent/HRP20110966T1/hr unknown
- 2005-08-11 ME MEP-2011-184A patent/ME01264B/me unknown
- 2005-08-11 WO PCT/EP2005/008735 patent/WO2006018221A1/de not_active Ceased
- 2005-08-11 KR KR1020077005957A patent/KR101235092B1/ko not_active Expired - Fee Related
- 2005-08-11 EP EP05778137A patent/EP1778238B1/de not_active Expired - Lifetime
- 2005-08-11 CN CNA2005800352739A patent/CN101039676A/zh active Pending
- 2005-08-11 NZ NZ553815A patent/NZ553815A/en not_active IP Right Cessation
- 2005-08-11 DK DK05778137.9T patent/DK1778238T3/da active
- 2005-08-11 UA UAA200702575A patent/UA92470C2/ru unknown
- 2005-08-11 BR BRPI0513997-0A patent/BRPI0513997A/pt active Search and Examination
- 2005-08-11 CA CA2575821A patent/CA2575821C/en not_active Expired - Lifetime
- 2005-08-11 PT PT05778137T patent/PT1778238E/pt unknown
- 2005-08-11 CN CN201610003590.2A patent/CN105640874A/zh active Pending
- 2005-08-11 SI SI200531439T patent/SI1778238T1/sl unknown
- 2005-08-11 AU AU2005274339A patent/AU2005274339B2/en not_active Ceased
- 2005-08-11 RS RS20110504A patent/RS52043B/sr unknown
- 2005-08-11 JP JP2007526359A patent/JP5048491B2/ja not_active Expired - Lifetime
- 2005-08-11 AT AT05778137T patent/ATE528007T1/de active
- 2005-08-11 MX MX2007001855A patent/MX2007001855A/es active IP Right Grant
- 2005-08-11 ES ES05778137T patent/ES2375980T3/es not_active Expired - Lifetime
- 2005-08-12 PE PE2005000937A patent/PE20060645A1/es not_active Application Discontinuation
- 2005-08-12 TW TW094127587A patent/TWI371278B/zh not_active IP Right Cessation
- 2005-08-12 PE PE2009001171A patent/PE20100447A1/es not_active Application Discontinuation
- 2005-08-12 UY UY29060A patent/UY29060A1/es not_active Application Discontinuation
- 2005-08-12 PE PE2009000399A patent/PE20091583A1/es not_active Application Discontinuation
- 2005-08-12 MY MYPI20053807A patent/MY147799A/en unknown
- 2005-08-12 AR ARP050103382A patent/AR050918A1/es unknown
2007
- 2007-01-15 ZA ZA200700425A patent/ZA200700425B/xx unknown
- 2007-02-13 IL IL181306A patent/IL181306A/en not_active IP Right Cessation
- 2007-02-14 EC EC2007007250A patent/ECSP077250A/es unknown
- 2007-02-21 NO NO20070984A patent/NO20070984L/no not_active Application Discontinuation
2009
- 2009-02-06 US US12/366,730 patent/US8445675B2/en active Active
2012
- 2012-01-05 CY CY20121100009T patent/CY1112211T1/el unknown
2013
- 2013-04-23 US US13/868,591 patent/US20130245013A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DK1778238T3 (da)	2012-02-06
ES2375980T3 (es)	2012-03-07
NZ553815A (en)	2010-12-24
SI1778238T1 (sl)	2012-02-29
ME01264B (me)	2013-06-20
KR20070053253A (ko)	2007-05-23
NO20070984L (no)	2007-05-10
BRPI0513997A (pt)	2008-05-20
PE20091583A1 (es)	2009-11-14
TWI371278B (en)	2012-09-01
CN105640874A (zh)	2016-06-08
US20090143379A1 (en)	2009-06-04
PL1778238T3 (pl)	2012-03-30
JP5048491B2 (ja)	2012-10-17
PE20060645A1 (es)	2006-08-01
US20130245013A1 (en)	2013-09-19
JP2008509952A (ja)	2008-04-03
MX2007001855A (es)	2007-03-28
ECSP077250A (es)	2007-03-29
EA200700389A1 (ru)	2007-08-31
UA92470C2 (ru)	2010-11-10
IL181306A (en)	2014-07-31
WO2006018221A1 (de)	2006-02-23
CY1112211T1 (el)	2015-12-09
PT1778238E (pt)	2011-11-25
HRP20110966T1 (hr)	2012-01-31
CA2575821A1 (en)	2006-02-23
CA2575821C (en)	2013-07-02
UY29060A1 (es)	2006-03-31
KR101235092B1 (ko)	2013-02-20
EA014237B1 (ru)	2010-10-29
AR050918A1 (es)	2006-12-06
US20060035903A1 (en)	2006-02-16
PE20100447A1 (es)	2010-06-25
WO2006018221A8 (de)	2006-06-15
AU2005274339B2 (en)	2011-05-19
TW200628157A (en)	2006-08-16
AU2005274339A1 (en)	2006-02-23
CN101039676A (zh)	2007-09-19
EP1778238B1 (de)	2011-10-12
ATE528007T1 (de)	2011-10-15
MY147799A (en)	2013-01-31
EP1778238A1 (de)	2007-05-02
IL181306A0 (en)	2007-07-04
RS52043B (sr)	2012-04-30
US8445675B2 (en)	2013-05-21
WO2006018221A9 (de)	2011-04-28

Publication	Publication Date	Title
ZA200700425B (en)	2008-10-29	Dihydropteridinone infusion solution having a long shelf life
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AU157218S (en)	2005-01-10	A shelf
AU157372S (en)	2005-01-28	A shelf
ZAF200501779S (en)	2006-07-26	A shelf
ZAF200500429S (en)	2007-02-13	A medicament holder
AU156869S (en)	2004-11-15	Shelving
AU156868S (en)	2004-11-15	Shelving
GB0409954D0 (en)	2004-06-09	A novel medicament