ZA200700368B - Retinal derivatives and methods for the use thereof for the treatment of visual disorders - Google Patents

Retinal derivatives and methods for the use thereof for the treatment of visual disorders

Info

Publication number: ZA200700368B
Authority: ZA; South Africa
Prior art keywords: treatment; methods; visual disorders; retinal derivatives; retinal
Prior art date: 2004-06-18

Application number

ZA200700368A

Other languages

English (en)

Inventor

Palczewski Krzysztof

Batten Matthew

Original Assignee

Univ Washington

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-18

Filing date

2005-06-20

Publication date

2008-10-29

2005-06-20 Application filed by Univ Washington filed Critical Univ Washington

2008-10-29 Publication of ZA200700368B publication Critical patent/ZA200700368B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/10—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by etherified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Ophthalmology & Optometry (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Dermatology (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA200700368A 2004-06-18 2005-06-20 Retinal derivatives and methods for the use thereof for the treatment of visual disorders ZA200700368B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US58088904P	2004-06-18	2004-06-18

Publications (1)

Publication Number	Publication Date
ZA200700368B true ZA200700368B (en)	2008-10-29

Family

ID=35782277

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200700368A ZA200700368B (en)	2004-06-18	2005-06-20	Retinal derivatives and methods for the use thereof for the treatment of visual disorders

Country Status (26)

Country	Link
US (8)	US7951841B2 (xx)
EP (5)	EP2397131B1 (xx)
JP (2)	JP5166026B2 (xx)
KR (4)	KR20140140616A (xx)
CN (2)	CN1988898B (xx)
AU (1)	AU2005257997B2 (xx)
BR (1)	BRPI0511396B1 (xx)
CA (2)	CA2571049C (xx)
CY (2)	CY1114873T1 (xx)
DK (2)	DK1765322T3 (xx)
ES (4)	ES2443194T3 (xx)
HR (1)	HRP20140116T1 (xx)
HU (1)	HUE036596T2 (xx)
IL (4)	IL180078A (xx)
IN (1)	IN2012DN09335A (xx)
LT (1)	LT2397133T (xx)
MX (2)	MX359668B (xx)
NO (1)	NO339969B1 (xx)
NZ (2)	NZ587006A (xx)
PL (2)	PL2397133T3 (xx)
PT (2)	PT1765322E (xx)
RS (1)	RS53178B (xx)
RU (2)	RU2408578C2 (xx)
SI (2)	SI1765322T1 (xx)
WO (1)	WO2006002097A2 (xx)
ZA (1)	ZA200700368B (xx)

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2005
- 2005-06-20 RU RU2007101735/04A patent/RU2408578C2/ru active
- 2005-06-20 EP EP11163940.7A patent/EP2397131B1/en not_active Expired - Lifetime
- 2005-06-20 ES ES05773576.3T patent/ES2443194T3/es not_active Expired - Lifetime
- 2005-06-20 EP EP11163943.1A patent/EP2397132B1/en not_active Expired - Lifetime
- 2005-06-20 NZ NZ587006A patent/NZ587006A/en not_active IP Right Cessation
- 2005-06-20 PL PL11163947T patent/PL2397133T3/pl unknown
- 2005-06-20 CA CA2571049A patent/CA2571049C/en not_active Expired - Fee Related
- 2005-06-20 HU HUE11163947A patent/HUE036596T2/hu unknown
- 2005-06-20 SI SI200531827T patent/SI1765322T1/sl unknown
- 2005-06-20 EP EP11163939.9A patent/EP2397130B1/en not_active Expired - Lifetime
- 2005-06-20 HR HRP20140116TT patent/HRP20140116T1/hr unknown
- 2005-06-20 MX MX2012003410A patent/MX359668B/es unknown
- 2005-06-20 CN CN2005800240983A patent/CN1988898B/zh not_active Expired - Fee Related
- 2005-06-20 ES ES11163943.1T patent/ES2644981T3/es not_active Expired - Lifetime
- 2005-06-20 PT PT57735763T patent/PT1765322E/pt unknown
- 2005-06-20 AU AU2005257997A patent/AU2005257997B2/en not_active Ceased
- 2005-06-20 LT LTEP11163947.2T patent/LT2397133T/lt unknown
- 2005-06-20 ZA ZA200700368A patent/ZA200700368B/xx unknown
- 2005-06-20 PT PT111639472T patent/PT2397133T/pt unknown
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- 2005-06-20 KR KR1020147030120A patent/KR20140140616A/ko not_active Ceased
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- 2005-06-20 SI SI200532176T patent/SI2397133T1/sl unknown
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- 2005-06-20 DK DK05773576.3T patent/DK1765322T3/da active
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Also Published As

Publication number	Publication date
HRP20140116T1 (hr)	2014-03-28
LT2397133T (lt)	2018-01-10
EP2397132A2 (en)	2011-12-21
JP5166026B2 (ja)	2013-03-21
MX359668B (es)	2018-10-05
CN1988898A (zh)	2007-06-27
RU2408578C2 (ru)	2011-01-10
US20110288170A1 (en)	2011-11-24
US9174936B2 (en)	2015-11-03
EP1765322A2 (en)	2007-03-28
DK1765322T3 (da)	2014-02-10
EP2397131A3 (en)	2012-10-31
IL230242A (en)	2015-10-29
BRPI0511396A (pt)	2007-12-04
NO20070330L (no)	2007-03-15
IL180078A (en)	2014-01-30
KR20130079669A (ko)	2013-07-10
RS53178B (sr)	2014-06-30
EP2397133A3 (en)	2012-07-11
MXPA06014750A (es)	2007-03-21
IL230241A (en)	2015-06-30
EP2397130A2 (en)	2011-12-21
IL222347A (en)	2017-08-31
JP2008503496A (ja)	2008-02-07
KR101490145B1 (ko)	2015-02-05
EP2397133B1 (en)	2017-07-26
IL180078A0 (en)	2007-05-15
ES2443194T3 (es)	2014-02-18
US7951841B2 (en)	2011-05-31
US20130072560A1 (en)	2013-03-21
CA2571049C (en)	2016-08-09
PT1765322E (pt)	2014-02-05
IN2012DN09335A (xx)	2015-08-21
JP2012229234A (ja)	2012-11-22
US20130079403A1 (en)	2013-03-28
US20190167626A1 (en)	2019-06-06
EP2397132A3 (en)	2012-07-11
ES2644981T3 (es)	2017-12-01
HUE036596T2 (hu)	2018-07-30
PL2397133T3 (pl)	2018-01-31
BRPI0511396B1 (pt)	2021-07-27
CN1988898B (zh)	2012-12-26
US9169204B2 (en)	2015-10-27
NZ587006A (en)	2011-12-22
CN102976937B (zh)	2016-12-21
ES2644984T3 (es)	2017-12-01
US10117845B2 (en)	2018-11-06
RU2010138410A (ru)	2012-03-27
WO2006002097A2 (en)	2006-01-05
AU2005257997B2 (en)	2012-04-05
SI2397133T1 (sl)	2017-12-29
DK2397133T3 (en)	2017-10-30
EP2397132B1 (en)	2017-07-26
EP1765322B1 (en)	2013-11-06
NO339969B1 (no)	2017-02-20
PL1765322T3 (pl)	2014-04-30
HK1098696A1 (en)	2007-07-27
KR20140140616A (ko)	2014-12-09
AU2005257997A1 (en)	2006-01-05
CA2931917A1 (en)	2006-01-05
US9403765B2 (en)	2016-08-02
CY1114873T1 (el)	2016-12-14
CY1119480T1 (el)	2018-03-07
EP2397131A2 (en)	2011-12-21
KR20070026817A (ko)	2007-03-08
CN102976937A (zh)	2013-03-20
EP2397131B1 (en)	2019-09-11
EP2397133A2 (en)	2011-12-21
KR101337321B1 (ko)	2013-12-06
KR20120062946A (ko)	2012-06-14
EP2397130A3 (en)	2012-10-31
US20170014368A1 (en)	2017-01-19
US9162978B2 (en)	2015-10-20
KR101323122B1 (ko)	2013-10-30
US20130072559A1 (en)	2013-03-21
SI1765322T1 (sl)	2014-03-31
US9388130B2 (en)	2016-07-12
JP5596749B2 (ja)	2014-09-24
CA2571049A1 (en)	2006-01-05
NZ552080A (en)	2011-03-31
PT2397133T (pt)	2017-10-23
WO2006002097A3 (en)	2006-05-04
EP1765322A4 (en)	2008-09-17
RU2007101735A (ru)	2008-07-27
US20130072556A1 (en)	2013-03-21
US20080221208A1 (en)	2008-09-11
EP2397130B1 (en)	2019-04-03
ES2752924T3 (es)	2020-04-06
RU2554003C2 (ru)	2015-06-20

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