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ZA200709501B - Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors - Google Patents

Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors

Info

Publication number
ZA200709501B
ZA200709501B ZA200700950A ZA200709501A ZA200709501B ZA 200709501 B ZA200709501 B ZA 200709501B ZA 200700950 A ZA200700950 A ZA 200700950A ZA 200709501 A ZA200709501 A ZA 200709501A ZA 200709501 B ZA200709501 B ZA 200709501B
Authority
ZA
South Africa
Prior art keywords
azolopyridine
lipase
derivatives
phospholipase inhibitors
phospholipase
Prior art date
Application number
ZA200700950A
Other languages
English (en)
Inventor
Zoller Gerhard
Petry Stefan
Mueller Guenter
Heuer Hubert
Tennagels Norbert
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of ZA200709501B publication Critical patent/ZA200709501B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA200700950A 2005-06-09 2007-11-05 Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors ZA200709501B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005026762A DE102005026762A1 (de) 2005-06-09 2005-06-09 Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen

Publications (1)

Publication Number Publication Date
ZA200709501B true ZA200709501B (en) 2008-10-29

Family

ID=37076291

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200700950A ZA200709501B (en) 2005-06-09 2007-11-05 Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors

Country Status (30)

Country Link
US (2) US7846943B2 (xx)
EP (1) EP1896485B1 (xx)
JP (1) JP2008542410A (xx)
KR (1) KR20080019215A (xx)
CN (1) CN101193896A (xx)
AR (1) AR054132A1 (xx)
AT (1) ATE468342T1 (xx)
AU (1) AU2006257022A1 (xx)
BR (1) BRPI0611688A2 (xx)
CA (1) CA2610325A1 (xx)
CY (1) CY1110213T1 (xx)
DE (2) DE102005026762A1 (xx)
DK (1) DK1896485T3 (xx)
ES (1) ES2346561T3 (xx)
HR (1) HRP20100409T1 (xx)
IL (1) IL187730A0 (xx)
MA (1) MA29481B1 (xx)
MX (1) MX2007015347A (xx)
MY (1) MY142792A (xx)
NO (1) NO20080133L (xx)
NZ (1) NZ564063A (xx)
PL (1) PL1896485T3 (xx)
PT (1) PT1896485E (xx)
RS (1) RS51268B (xx)
RU (1) RU2414473C2 (xx)
SI (1) SI1896485T1 (xx)
TW (1) TW200716653A (xx)
UY (1) UY29593A1 (xx)
WO (1) WO2006131231A1 (xx)
ZA (1) ZA200709501B (xx)

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DE102006014685A1 (de) 2006-03-28 2007-10-04 Sanofi-Aventis Imidazo-pyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholiphasen
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
UY31968A (es) 2008-07-09 2010-01-29 Sanofi Aventis Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
US8957219B2 (en) 2008-10-17 2015-02-17 Shionogi & Co., Ltd. Acetic acid amide derivative having inhibitory activity on endothelial lipase
WO2011059839A1 (en) * 2009-10-29 2011-05-19 Sirtris Pharmaceuticals, Inc. Bicyclic pyridines and analogs as sirtuin modulators
EP2514749B1 (en) 2009-12-15 2015-02-25 Shionogi & Co., Ltd. Oxadiazole derivative having endothelial lipase inhibitory activity
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
CN114560873B (zh) * 2021-12-27 2023-02-28 浙江日出药业有限公司 一种3-氯甲基-6-氯-噁唑[4,5-b]吡啶-2(3H)酮的制备方法

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Also Published As

Publication number Publication date
PT1896485E (pt) 2010-08-05
MA29481B1 (fr) 2008-05-02
RS51268B (sr) 2010-12-31
DE502006006986D1 (de) 2010-07-01
MY142792A (en) 2010-12-31
CA2610325A1 (en) 2006-12-14
RU2414473C2 (ru) 2011-03-20
AR054132A1 (es) 2007-06-06
JP2008542410A (ja) 2008-11-27
CY1110213T1 (el) 2012-05-23
IL187730A0 (en) 2008-08-07
SI1896485T1 (sl) 2010-09-30
US20110039883A1 (en) 2011-02-17
AU2006257022A1 (en) 2006-12-14
EP1896485A1 (de) 2008-03-12
US7846943B2 (en) 2010-12-07
DE102005026762A1 (de) 2006-12-21
WO2006131231A1 (de) 2006-12-14
ES2346561T3 (es) 2010-10-18
ATE468342T1 (de) 2010-06-15
BRPI0611688A2 (pt) 2010-09-28
EP1896485B1 (de) 2010-05-19
PL1896485T3 (pl) 2010-10-29
HRP20100409T1 (hr) 2010-09-30
RU2007145499A (ru) 2009-06-20
NO20080133L (no) 2008-03-05
TW200716653A (en) 2007-05-01
US20080167339A1 (en) 2008-07-10
DK1896485T3 (da) 2010-09-06
MX2007015347A (es) 2008-02-15
CN101193896A (zh) 2008-06-04
UY29593A1 (es) 2007-01-31
NZ564063A (en) 2010-07-30
KR20080019215A (ko) 2008-03-03

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