ZA200704784B - Methods and compositions using immunomodulatory compounds for treatment and management of parasitic diseases - Google Patents

Methods and compositions using immunomodulatory compounds for treatment and management of parasitic diseases

Info

Publication number: ZA200704784B
Authority: ZA; South Africa
Prior art keywords: compositions; management; treatment; methods; parasitic diseases
Prior art date: 2004-11-12

Application number

ZA200704784A

Other languages

English (en)

Inventor

Hensel Jennifer

Original Assignee

Celgene Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-12

Filing date

2005-11-08

Publication date

2008-10-29

2005-11-08 Application filed by Celgene Corp filed Critical Celgene Corp

2008-10-29 Publication of ZA200704784B publication Critical patent/ZA200704784B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/29—Antimony or bismuth compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Tropical Medicine & Parasitology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA200704784A 2004-11-12 2005-11-08 Methods and compositions using immunomodulatory compounds for treatment and management of parasitic diseases ZA200704784B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US62697504P	2004-11-12	2004-11-12

Publications (1)

Publication Number	Publication Date
ZA200704784B true ZA200704784B (en)	2008-10-29

Family

ID=36123326

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200704784A ZA200704784B (en)	2004-11-12	2005-11-08	Methods and compositions using immunomodulatory compounds for treatment and management of parasitic diseases

Country Status (13)

Country	Link
US (1)	US20060154880A1 (xx)
EP (1)	EP1814543A2 (xx)
JP (1)	JP2008519844A (xx)
KR (1)	KR20070086000A (xx)
CN (1)	CN101098694A (xx)
AR (1)	AR051766A1 (xx)
AU (1)	AU2005304420A1 (xx)
BR (1)	BRPI0517481A (xx)
CA (1)	CA2586950A1 (xx)
IL (1)	IL183115A0 (xx)
MX (1)	MX2007005570A (xx)
WO (1)	WO2006053160A2 (xx)
ZA (1)	ZA200704784B (xx)

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CN102898416A (zh)	2006-09-26	2013-01-30	细胞基因公司	作为抗肿瘤剂的5-取代的喹唑酮衍生物
WO2008057253A2 (en) *	2006-10-27	2008-05-15	Bioresponse, L.L.C.	Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles
KR101593242B1 (ko)	2007-09-26	2016-02-11	셀진 코포레이션	６-, ７- 또는 ８-치환된 퀴나졸리논 유도체, 및 그를 포함하는 조성물 및 그의 사용 방법
KR20110010763A (ko) *	2008-05-09	2011-02-07	톨마 인코포레이티드	피부/점막 질환을 치료하기 위한 프로구아닐
US20090298882A1 (en) *	2008-05-13	2009-12-03	Muller George W	Thioxoisoindoline compounds and compositions comprising and methods of using the same
DE102008031284A1 (de) *	2008-07-02	2010-01-07	Bayer Schering Pharma Aktiengesellschaft	Neue Bekämpfungsmöglichkeit der Giardiose
DE102008031283A1 (de) *	2008-07-02	2010-01-07	Bayer Schering Pharma Aktiengesellschaft	Neue Bekämpfungsmöglichkeit von durch Trichomonadida hervorgerufenen Krankheiten
US8110578B2 (en)	2008-10-27	2012-02-07	Signal Pharmaceuticals, Llc	Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
PE20140963A1 (es)	2008-10-29	2014-08-06	Celgene Corp	Compuestos de isoindolina para el tratamiento de cancer
EP2396312A1 (en)	2009-02-11	2011-12-21	Celgene Corporation	Isotopologues of lenalidomide
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CN101696205B (zh)	2009-11-02	2011-10-19	南京卡文迪许生物工程技术有限公司	3-(取代二氢异吲哚-2-基)-2,6-哌啶二酮多晶型物和药用组合物
BR112012015129A2 (pt)	2009-12-22	2019-09-24	Celgene Corp	"composto, composição farmacêutica e método para tratar, controlar ou prevenir uma doença ou distúrbio"
SG10201501062SA (en)	2010-02-11	2015-04-29	Celgene Corp	Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
WO2012079075A1 (en)	2010-12-10	2012-06-14	Concert Pharmaceuticals, Inc.	Deuterated phthalimide derivatives
CN103402980B (zh)	2011-01-10	2016-06-29	细胞基因公司	作为pde4和/或细胞因子抑制剂的苯乙基砜异吲哚啉衍生物
EA026100B1 (ru)	2011-03-11	2017-03-31	Селджин Корпорейшн	Твердые формы 3-(5-амино-2-метил-4-оксо-4н-хиназолин-3-ил)пиперидин-2,6-диона и их фармацевтические композиции и применение
AU2012236655B2 (en)	2011-03-28	2016-09-22	Deuterx, Llc,	2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds
US20140221427A1 (en)	2011-06-22	2014-08-07	Celgene Corporation	Isotopologues of pomalidomide
PH12014500593A1 (en)	2011-09-14	2019-09-02	Celgene Corp	Formulations of cyclopropanecarboxylic acid {2-(1s)-1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-oxo-2,3-dihydro-1h-isoindol-4-yl}-amidecelgene corporation state of incorporation:delaware
SG10201605251VA (en)	2011-12-27	2016-08-30	Celgene Corp	Formulations of (+)-2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-4-acetylaminoisoindoline-1,3-dione
WO2013130849A1 (en)	2012-02-29	2013-09-06	Concert Pharmaceuticals, Inc.	Substituted dioxopiperidinyl phthalimide derivatives
WO2013159026A1 (en)	2012-04-20	2013-10-24	Concert Pharmaceuticals, Inc.	Deuterated rigosertib
PE20150617A1 (es)	2012-08-09	2015-05-21	Celgene Corp	Formas solidas de 3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona o un estereoisomero del mismo, de sus sales, y composiciones que comprenden las mismas
CN103697430A (zh) *	2012-09-27	2014-04-02	海洋王（东莞）照明科技有限公司	灯具脚架连接结构
WO2014066243A1 (en)	2012-10-22	2014-05-01	Concert Pharmaceuticals, Inc.	Solid forms of {s-3-(4-amino-1-oxo-isoindolin-2yl)(piperidine-3,4,4,5,5-d5)-2,6-dione}
WO2014110322A2 (en)	2013-01-11	2014-07-17	Concert Pharmaceuticals, Inc.	Substituted dioxopiperidinyl phthalimide derivatives
CA2935495C (en)	2013-01-14	2021-04-20	Deuterx, Llc	3-(5-substituted-4-oxoquinazolin-3(4h)-yl)-3-deutero-piperidine-2,6-dione derivatives
WO2014116573A1 (en)	2013-01-22	2014-07-31	Celgene Corporation	Processes for the preparation of isotopologues of 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable salts thereof
EP2764866A1 (en)	2013-02-07	2014-08-13	IP Gesellschaft für Management mbH	Inhibitors of nedd8-activating enzyme
EP2968334A4 (en)	2013-03-14	2016-08-03	Deuterx Llc	3- (SUBSTITIERTES-4-OXO-quinazolin-3 (4H) -yl) -3-deutero-PIPERIDINE-2,6-DIONE DERIVATIVES
UA117141C2 (uk)	2013-10-08	2018-06-25	Селджин Корпорейшн	Склади (s)-3-(4-((4-(морфолінометил)бензил)оксі)-1-оксоізоіндолін-2-іл)піперидин-2,6-діону
TW201540323A (zh)	2014-01-15	2015-11-01	Celgene Corp	３－（５－胺基－２－甲基－４－側氧基－４ｈ－喹唑啉－３－基）－哌啶－２，６－二酮之調配物
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2005
- 2005-11-08 KR KR1020077013085A patent/KR20070086000A/ko not_active Withdrawn
- 2005-11-08 JP JP2007541327A patent/JP2008519844A/ja active Pending
- 2005-11-08 CN CNA2005800463712A patent/CN101098694A/zh active Pending
- 2005-11-08 MX MX2007005570A patent/MX2007005570A/es unknown
- 2005-11-08 ZA ZA200704784A patent/ZA200704784B/xx unknown
- 2005-11-08 BR BRPI0517481-3A patent/BRPI0517481A/pt not_active Application Discontinuation
- 2005-11-08 EP EP05848864A patent/EP1814543A2/en not_active Withdrawn
- 2005-11-08 WO PCT/US2005/040823 patent/WO2006053160A2/en not_active Ceased
- 2005-11-08 AU AU2005304420A patent/AU2005304420A1/en not_active Abandoned
- 2005-11-08 CA CA002586950A patent/CA2586950A1/en not_active Abandoned
- 2005-11-11 AR ARP050104761A patent/AR051766A1/es not_active Application Discontinuation
- 2005-11-14 US US11/271,963 patent/US20060154880A1/en not_active Abandoned
2007
- 2007-05-10 IL IL183115A patent/IL183115A0/en unknown

Also Published As

Publication number	Publication date
CA2586950A1 (en)	2006-05-18
AU2005304420A1 (en)	2006-05-18
US20060154880A1 (en)	2006-07-13
EP1814543A2 (en)	2007-08-08
CN101098694A (zh)	2008-01-02
BRPI0517481A (pt)	2008-10-14
AR051766A1 (es)	2007-02-07
IL183115A0 (en)	2008-04-13
KR20070086000A (ko)	2007-08-27
MX2007005570A (es)	2007-07-09
WO2006053160A3 (en)	2006-06-29
WO2006053160A2 (en)	2006-05-18
JP2008519844A (ja)	2008-06-12

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