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ZA200704650B - 4-cycloalkyl-substituted tetrahydrochinoline derivatives and use thereof as medicaments - Google Patents

4-cycloalkyl-substituted tetrahydrochinoline derivatives and use thereof as medicaments

Info

Publication number
ZA200704650B
ZA200704650B ZA200704650A ZA200704650A ZA200704650B ZA 200704650 B ZA200704650 B ZA 200704650B ZA 200704650 A ZA200704650 A ZA 200704650A ZA 200704650 A ZA200704650 A ZA 200704650A ZA 200704650 B ZA200704650 B ZA 200704650B
Authority
ZA
South Africa
Prior art keywords
medicaments
cycloalkyl
substituted
tetrahydrochinoline
derivatives
Prior art date
Application number
ZA200704650A
Inventor
Bischoff Hilmar
Gielen-Haertwig Heike
Li Volkhart
Schmeck Carsten
Thutewohl Michael
Vakalopoulos Alexandros
Weber Olaf
Wuttke Martina
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of ZA200704650B publication Critical patent/ZA200704650B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200704650A 2004-12-18 2006-12-15 4-cycloalkyl-substituted tetrahydrochinoline derivatives and use thereof as medicaments ZA200704650B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004060997A DE102004060997A1 (en) 2004-12-18 2004-12-18 New tetrahydroquinoline compounds are cholesterol ester transfer protein inhibitors useful for primary and/or secondary prevention of coronary heart disease; and for treatment and/or prevention of e.g. hypolipoproteinemia and dyslipidemia

Publications (1)

Publication Number Publication Date
ZA200704650B true ZA200704650B (en) 2008-12-31

Family

ID=36571204

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200704650A ZA200704650B (en) 2004-12-18 2006-12-15 4-cycloalkyl-substituted tetrahydrochinoline derivatives and use thereof as medicaments

Country Status (3)

Country Link
CN (1) CN101124206B (en)
DE (1) DE102004060997A1 (en)
ZA (1) ZA200704650B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2010140442A (en) * 2008-03-05 2012-04-10 Бёрингер Ингельхайм Интернациональ Гмбх (De) TRICYCLIC DERIVATIVES OF PYRIDINE, MEDICINES CONTAINING SUCH COMPOUNDS, THEIR USE AND METHOD FOR PRODUCING THEREOF
EP2536733B1 (en) * 2010-02-19 2014-11-26 Boehringer Ingelheim International GmbH Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP970330B1 (en) * 1996-07-08 2004-06-30 Bayer Ag Cycloalkano pyridines

Also Published As

Publication number Publication date
DE102004060997A1 (en) 2006-06-22
CN101124206B (en) 2012-03-21
CN101124206A (en) 2008-02-13

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