ZA200609635B - Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers - Google Patents
Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancersInfo
- Publication number
- ZA200609635B ZA200609635B ZA200609635A ZA200609635A ZA200609635B ZA 200609635 B ZA200609635 B ZA 200609635B ZA 200609635 A ZA200609635 A ZA 200609635A ZA 200609635 A ZA200609635 A ZA 200609635A ZA 200609635 B ZA200609635 B ZA 200609635B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- liver diseases
- epithelial cancers
- mitochondrially targeted
- targeted antioxidants
- Prior art date
Links
- 201000009030 Carcinoma Diseases 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 title 1
- 208000019423 liver disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04103318 | 2004-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200609635B true ZA200609635B (en) | 2008-08-27 |
Family
ID=34929318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200609635A ZA200609635B (en) | 2004-07-13 | 2006-11-20 | Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20070225255A1 (fr) |
| EP (1) | EP1765413A2 (fr) |
| JP (1) | JP2008506667A (fr) |
| CN (1) | CN1997403A (fr) |
| AU (1) | AU2005261654A1 (fr) |
| CA (1) | CA2573456A1 (fr) |
| IL (1) | IL179738A0 (fr) |
| RU (1) | RU2007105138A (fr) |
| SG (1) | SG156613A1 (fr) |
| WO (1) | WO2006005759A2 (fr) |
| ZA (1) | ZA200609635B (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110522717A (zh) | 2004-01-22 | 2019-12-03 | 迈阿密大学 | 局部辅酶q10制剂及其使用方法 |
| US20080032940A1 (en) * | 2006-08-07 | 2008-02-07 | Balaraman Kalyanaraman | Methods for reducing anthracycline-induced toxicity |
| US8557733B2 (en) | 2006-10-20 | 2013-10-15 | Mitotech S.A. | Composition for regenerating and stimulating growth of plants and for adapting plants to different stress factors |
| US8658624B2 (en) | 2006-10-20 | 2014-02-25 | Mitotech Sa | Pharmaceutical compositions for preventing and treating eye pathologies |
| WO2008094061A1 (fr) * | 2007-01-29 | 2008-08-07 | Limited Liability Company 'mitotechnology' | Compositions pharmaceutiques et cosmétiques servant à accélérer le processus de cicatrisation de plaies et autres lésions superficielles |
| WO2008094062A1 (fr) | 2007-01-29 | 2008-08-07 | Limited Liability Company 'mitotechnology' | Compositions pharmaceutiques servant à la prévention et au traitement de maladies oncologiques |
| EA201000142A1 (ru) | 2007-04-11 | 2010-04-30 | Общество С Ограниченной Ответственностью "Митотехнология" | Композиция, замедляющая старение и увеличивающая продолжительность жизни организма, и ее применение |
| WO2009005386A1 (fr) | 2007-06-29 | 2009-01-08 | Limited Liability Company 'mitotechnology' | Utilisation de compositions à adressage mitochondrial dans la prévention et le traitement de maldies cardio-vasculaires |
| AU2008296012A1 (en) * | 2007-09-07 | 2009-03-12 | Gencia Corporation | Mitochondrial compositions and uses thereof |
| US8388936B2 (en) * | 2008-02-22 | 2013-03-05 | Mcw Research Foundation, Inc. | In vivo mitochondrial labeling using positively-charged nitroxide enhanced and gadolinium chelate enhanced magnetic resonance imaging |
| US8388931B2 (en) * | 2008-02-29 | 2013-03-05 | Marcos Lopez | 99m Tc-labeled triphenylphosphonium derivative contrasting agents and molecular probes for early detection and imaging of breast tumors |
| EP2271325A4 (fr) | 2008-04-11 | 2011-11-09 | Cytotech Labs Llc | Procédés et utilisation d'induction de l'apoptose dans des cellules cancéreuses |
| WO2010056145A1 (fr) | 2008-11-12 | 2010-05-20 | Общество С Ограниченной Ответственностью "Митотехнология" | Procédé d’accroissement mesuré de la conductivité de protons de membranes biologiques à l’aide de cations délocalisés adressés par voie mitochondriale |
| CA2756820A1 (fr) * | 2009-04-17 | 2010-10-21 | Colby Pharmaceutical Company | Compositions pharmaceutiquement actives comprenant des modulateurs de stress oxydatif (osm), nouvelles entites chimiques, compositions et utilisations |
| US20110020312A1 (en) | 2009-05-11 | 2011-01-27 | Niven Rajin Narain | Methods for treatment of metabolic disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers |
| KR101478728B1 (ko) | 2009-06-10 | 2015-01-02 | 리미티드 라이어빌러티 컴퍼니 미토테크 | 안과 및 수의 안과에서 사용하기 위한 약학적 조성물 |
| EP2500336A1 (fr) | 2009-11-13 | 2012-09-19 | Obschestvo S Ogranichennoi Otvetstvennostyu "Mitotekh" | Substances pharmaceutiques à base d'antioxydants adressés à des mitochondries |
| US20120269867A1 (en) | 2011-04-04 | 2012-10-25 | Jimenez Joaquin J | Methods of treating central nervous system tumors |
| JP6448366B2 (ja) | 2011-06-03 | 2019-01-09 | ミトテック ソシエテ アノニム | ミトコンドリアを標的とする抗酸化剤の経口製剤ならびにそれらの調製および使用 |
| AU2012312654B2 (en) | 2011-09-19 | 2017-04-13 | Gencia Corporation | Modified creatine compounds |
| EA032775B1 (ru) | 2013-04-08 | 2019-07-31 | Берг Ллк | Способы лечения злокачественной опухоли с использованием комбинированной терапии с коферментом q10 |
| MD4626C1 (ro) * | 2013-04-24 | 2019-11-30 | Smart Brain Sro | Derivaţi de tamoxifen pentru tratamentul afecţiunilor neoplazice, în special cu nivel înalt de proteină HER2 |
| US9901542B2 (en) | 2013-09-04 | 2018-02-27 | Berg Llc | Methods of treatment of cancer by continuous infusion of coenzyme Q10 |
| US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
| KR101773404B1 (ko) | 2015-08-25 | 2017-08-31 | (주) 씨유스킨 | 자외선에 의한 피부 손상의 예방 또는 개선을 위한 화장료 조성물 |
| WO2017087576A1 (fr) | 2015-11-16 | 2017-05-26 | Berg Llc | Procédés de traitement de gliome résistant au témozolomide utilisant la coenzyme q10 |
| CN107510848A (zh) * | 2016-06-15 | 2017-12-26 | 常州莱道斯生物医药科技有限公司 | 线粒体靶向制剂MitoPBN在防治糖尿病中的应用 |
| CN108201543A (zh) * | 2016-12-19 | 2018-06-26 | 北京福纳康生物技术有限公司 | 水溶性富勒烯结构在制备治疗脂肪肝的药物中的应用 |
| WO2021198786A1 (fr) * | 2020-04-03 | 2021-10-07 | Mitotech S.A. | Utilisation d'antioxydants ciblant les mitochondries pour traiter des états inflammatoires graves |
| CN115381804B (zh) * | 2022-08-10 | 2024-06-21 | 华南师大(清远)科技创新研究院有限公司 | 癸基泛醌在制备治疗肝纤维化药物中的应用 |
| CN117563560A (zh) * | 2023-12-06 | 2024-02-20 | 西南大学 | 一种高效去除汞的吸附材料及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9722361D0 (en) * | 1997-10-24 | 1997-12-17 | Pharma Nord Uk Ltd | Pharmaceutical formulation for treating liver disorders |
| US6331532B1 (en) * | 1998-11-25 | 2001-12-18 | University Of Otago | Mitochondrially targeted antioxidants |
| CA2354743A1 (fr) * | 2001-08-07 | 2003-02-07 | University Of Otago | Antioxydants cibles par des mitochondries |
| NZ513547A (en) * | 2001-08-13 | 2002-09-27 | Antipodean Biotechnology Ltd | Synthesis of triphenylphosphonium quinols (e.g. mitoquinol) and/or quinones (e.g. mitoquinone) |
| CA2536546C (fr) * | 2003-08-22 | 2012-10-02 | Antipodean Pharmaceuticals, Inc. | Derives de la mitoquinone utilises en tant qu'antioxydants cibles de maniere mitochondriale |
-
2005
- 2005-07-12 SG SG200906579-8A patent/SG156613A1/en unknown
- 2005-07-12 CA CA002573456A patent/CA2573456A1/fr not_active Abandoned
- 2005-07-12 RU RU2007105138/15A patent/RU2007105138A/ru unknown
- 2005-07-12 EP EP05775873A patent/EP1765413A2/fr not_active Withdrawn
- 2005-07-12 CN CNA2005800231931A patent/CN1997403A/zh active Pending
- 2005-07-12 US US11/632,149 patent/US20070225255A1/en not_active Abandoned
- 2005-07-12 JP JP2007520833A patent/JP2008506667A/ja not_active Withdrawn
- 2005-07-12 AU AU2005261654A patent/AU2005261654A1/en not_active Abandoned
- 2005-07-12 WO PCT/EP2005/053338 patent/WO2006005759A2/fr not_active Ceased
-
2006
- 2006-11-20 ZA ZA200609635A patent/ZA200609635B/xx unknown
- 2006-11-30 IL IL179738A patent/IL179738A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005261654A1 (en) | 2006-01-19 |
| RU2007105138A (ru) | 2008-08-20 |
| CN1997403A (zh) | 2007-07-11 |
| SG156613A1 (en) | 2009-11-26 |
| US20070225255A1 (en) | 2007-09-27 |
| WO2006005759A3 (fr) | 2006-05-11 |
| EP1765413A2 (fr) | 2007-03-28 |
| IL179738A0 (en) | 2007-05-15 |
| JP2008506667A (ja) | 2008-03-06 |
| WO2006005759A2 (fr) | 2006-01-19 |
| CA2573456A1 (fr) | 2006-01-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL179738A0 (en) | Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers | |
| EP1968607A4 (fr) | Traitement du cancer et d'autres maladies | |
| IL184047A0 (en) | Methods and compositions for treating amyloid-related diseases | |
| EP1749095A4 (fr) | Nouveaux cibles therapeutiques dans le cancer | |
| IL241756A0 (en) | Preparations and methods for the treatment of diseases of safty tumors | |
| IL181608A0 (en) | Cancer combination therapy comprising azd2171 and imatinib | |
| IL227841A0 (en) | Dihydropyridinones for the treatment of cancer | |
| EP1758595A4 (fr) | Utilisation de conjugues lipidiques dans le traitement de maladies | |
| EP1737482A4 (fr) | Compositions et methodes de traitement de maladies | |
| IL190332A0 (en) | Human antibodies against il13 and therapeutic uses | |
| IL182498A0 (en) | Therapeutic furopyrimidines and thienopyrimidines | |
| IL182643A0 (en) | Novel composition and methods for the treatment of immune related diseases | |
| IL191072A0 (en) | Therapeutic compositions and methods | |
| IL178012A0 (en) | Diphenyl-indol-2-on compounds and their use in the treatment of cancer | |
| GB0418328D0 (en) | Cancer methods and medicaments | |
| IL182652A0 (en) | Nitrobenzindoles and their use in cancer therapy | |
| EP2012798A4 (fr) | Utilisation d'inositol-tripyrophosphate dans le traitement des tumeurs et des maladies | |
| IL180278A0 (en) | Fused pyrimidones useful in the treatment and the prevention of cancer | |
| IL172294A0 (en) | Methods and compositions for interferon therapy | |
| GB0428170D0 (en) | Mono and Combination Therapy | |
| EP1805210A4 (fr) | Nouveaux peptides et procédés pour le traitement de maladie inflammatoire | |
| GB0407382D0 (en) | Therapeutic methods and means | |
| EP1778873A4 (fr) | Nouvelles cibles thérapeutiques contre le cancer | |
| EP1755669A4 (fr) | Methodes et compositions pour ciblage specifique de cellules du carcinome hepatocellulaire chez l'homme | |
| EP1973398A4 (fr) | Utilisation d'inositol-tripyrophosphate dans le traitement de tumeurs et de maladies |