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ZA200607251B - Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination - Google Patents

Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination

Info

Publication number
ZA200607251B
ZA200607251B ZA200607251A ZA200607251A ZA200607251B ZA 200607251 B ZA200607251 B ZA 200607251B ZA 200607251 A ZA200607251 A ZA 200607251A ZA 200607251 A ZA200607251 A ZA 200607251A ZA 200607251 B ZA200607251 B ZA 200607251B
Authority
ZA
South Africa
Prior art keywords
conjugates
protein
prepared
reductive amination
hydroxyalkyl starch
Prior art date
Application number
ZA200607251A
Other languages
English (en)
Inventor
Zander Norbert
Eichner Wolfram
Conradt Harald
Hacket Frank
Langer Klaus
Orlando Michele
Frank Ronald
Original Assignee
Fresenius Kabi De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi De Gmbh filed Critical Fresenius Kabi De Gmbh
Publication of ZA200607251B publication Critical patent/ZA200607251B/xx

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
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    • C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
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  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
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  • Biochemistry (AREA)
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  • Diabetes (AREA)
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  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
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  • Dermatology (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
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  • Urology & Nephrology (AREA)
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ZA200607251A 2004-03-11 2005-03-11 Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination ZA200607251B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04005855 2004-03-11

Publications (1)

Publication Number Publication Date
ZA200607251B true ZA200607251B (en) 2009-03-25

Family

ID=34924481

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200607251A ZA200607251B (en) 2004-03-11 2005-03-11 Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination

Country Status (17)

Country Link
US (1) US8287850B2 (xx)
EP (2) EP2336192A1 (xx)
JP (1) JP5191729B2 (xx)
KR (1) KR101186821B1 (xx)
CN (2) CN101659704A (xx)
AR (1) AR048035A1 (xx)
AU (1) AU2005225513B2 (xx)
BR (1) BRPI0508607A (xx)
CA (1) CA2558738C (xx)
DE (1) DE202005021885U1 (xx)
EA (1) EA010501B1 (xx)
IL (1) IL177730A (xx)
NO (1) NO20064631L (xx)
SG (1) SG151261A1 (xx)
TW (1) TWI417303B (xx)
WO (1) WO2005092928A1 (xx)
ZA (1) ZA200607251B (xx)

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DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
DE10209822A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
AU2003255406B2 (en) 2002-09-11 2009-09-10 Fresenius Kabi Deutschland Gmbh Hydroxyalkyl starch derivatives
WO2005014655A2 (en) * 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
US20080274948A1 (en) * 2003-08-08 2008-11-06 Fresenius Kabi Deutschland Gmbh Conjugates of Hydroxyalkyl Starch and G-Csf
WO2005092391A2 (en) * 2004-03-11 2005-10-06 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
SG151261A1 (en) 2004-03-11 2009-04-30 Fresenius Kabi De Gmbh Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
KR20070110902A (ko) * 2005-03-11 2007-11-20 프레제니우스 카비 도이치란트 게엠베하 비활성 출발 물질로부터 생물활성 당단백질의 생산
EP1762250A1 (en) * 2005-09-12 2007-03-14 Fresenius Kabi Deutschland GmbH Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine
JP2009544680A (ja) * 2006-07-25 2009-12-17 リポクセン テクノロジーズ リミテッド ポリサッカライドによるタンパク質のｎ末端誘導体化
PL2197919T3 (pl) 2007-08-27 2014-09-30 Ratiopharm Gmbh Ciekły preparat koniugatu G-CSF
EP2070950A1 (en) 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Hydroxyalkyl starch derivatives and process for their preparation
EP2070951A1 (en) 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Method for producing a hydroxyalkyl starch derivatives with two linkers
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CN102414277A (zh) * 2009-03-20 2012-04-11 Fp创新研究中心 具有新颖性质的纤维素材料
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WO2011051466A1 (en) 2009-11-02 2011-05-05 Novartis Ag Anti-idiotypic fibronectin-based binding molecules and uses thereof
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