ZA200300164B - Novel aniline derivatives. - Google Patents
Novel aniline derivatives. Download PDFInfo
- Publication number
- ZA200300164B ZA200300164B ZA200300164A ZA200300164A ZA200300164B ZA 200300164 B ZA200300164 B ZA 200300164B ZA 200300164 A ZA200300164 A ZA 200300164A ZA 200300164 A ZA200300164 A ZA 200300164A ZA 200300164 B ZA200300164 B ZA 200300164B
- Authority
- ZA
- South Africa
- Prior art keywords
- methyl
- phenyl
- hexyloxy
- amino
- alkyl
- Prior art date
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- 125000002490 anilino group Chemical class [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims description 66
- -1 AS is lower-alkyl Chemical group 0.000 claims description 21
- 239000001257 hydrogen Substances 0.000 claims description 19
- 229910052739 hydrogen Inorganic materials 0.000 claims description 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 13
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 12
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 12
- 238000011282 treatment Methods 0.000 claims description 12
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 11
- 238000011321 prophylaxis Methods 0.000 claims description 11
- 125000003118 aryl group Chemical group 0.000 claims description 9
- 150000002148 esters Chemical class 0.000 claims description 8
- 229910052717 sulfur Inorganic materials 0.000 claims description 8
- 208000035150 Hypercholesterolemia Diseases 0.000 claims description 7
- 206010012601 diabetes mellitus Diseases 0.000 claims description 7
- 201000010099 disease Diseases 0.000 claims description 7
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 7
- 150000002367 halogens Chemical group 0.000 claims description 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 7
- 230000003463 hyperproliferative effect Effects 0.000 claims description 7
- 150000003839 salts Chemical class 0.000 claims description 7
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- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 6
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- 201000001883 cholelithiasis Diseases 0.000 claims description 6
- 201000005577 familial hyperlipidemia Diseases 0.000 claims description 6
- 208000001130 gallstones Diseases 0.000 claims description 6
- 125000001072 heteroaryl group Chemical group 0.000 claims description 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims description 5
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 5
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- 125000003342 alkenyl group Chemical group 0.000 claims description 5
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- 238000004519 manufacturing process Methods 0.000 claims description 4
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- 125000001424 substituent group Chemical group 0.000 claims description 4
- 230000001225 therapeutic effect Effects 0.000 claims description 4
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims description 3
- 125000002947 alkylene group Chemical group 0.000 claims description 3
- 238000002560 therapeutic procedure Methods 0.000 claims description 3
- NVOFYDRGGTYCGK-UHFFFAOYSA-N (4-chlorophenyl) n-[4-[4-(diethylamino)butoxy]phenyl]-n-methylcarbamate Chemical compound C1=CC(OCCCCN(CC)CC)=CC=C1N(C)C(=O)OC1=CC=C(Cl)C=C1 NVOFYDRGGTYCGK-UHFFFAOYSA-N 0.000 claims description 2
- IRDYTEMVLCAUJD-UHFFFAOYSA-N (4-chlorophenyl) n-[4-[4-[ethyl(2-hydroxyethyl)amino]butoxy]phenyl]-n-methylcarbamate Chemical compound C1=CC(OCCCCN(CCO)CC)=CC=C1N(C)C(=O)OC1=CC=C(Cl)C=C1 IRDYTEMVLCAUJD-UHFFFAOYSA-N 0.000 claims description 2
- UKLUOESQZSBGSM-UHFFFAOYSA-N (4-chlorophenyl) n-[4-[5-(dimethylamino)pent-1-ynyl]phenyl]-n-methylcarbamate Chemical compound C1=CC(C#CCCCN(C)C)=CC=C1N(C)C(=O)OC1=CC=C(Cl)C=C1 UKLUOESQZSBGSM-UHFFFAOYSA-N 0.000 claims description 2
- 125000004199 4-trifluoromethylphenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C(F)(F)F 0.000 claims description 2
- 125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 claims description 2
- VVGKXBSWMPHYEN-UHFFFAOYSA-N n-[4-[4-(diethylamino)butoxy]phenyl]-n-methyl-4-(trifluoromethyl)benzenesulfonamide Chemical compound C1=CC(OCCCCN(CC)CC)=CC=C1N(C)S(=O)(=O)C1=CC=C(C(F)(F)F)C=C1 VVGKXBSWMPHYEN-UHFFFAOYSA-N 0.000 claims description 2
- UQNXRYMCAXUTSO-UHFFFAOYSA-N n-[4-[4-(dimethylamino)butoxy]phenyl]-n-ethyl-4-(trifluoromethyl)benzenesulfonamide Chemical compound C=1C=C(C(F)(F)F)C=CC=1S(=O)(=O)N(CC)C1=CC=C(OCCCCN(C)C)C=C1 UQNXRYMCAXUTSO-UHFFFAOYSA-N 0.000 claims description 2
- WVUVTMQIFSNKAS-UHFFFAOYSA-N n-[4-[4-(dimethylamino)butoxy]phenyl]-n-methyl-4-(trifluoromethyl)benzenesulfonamide Chemical compound C1=CC(OCCCCN(C)C)=CC=C1N(C)S(=O)(=O)C1=CC=C(C(F)(F)F)C=C1 WVUVTMQIFSNKAS-UHFFFAOYSA-N 0.000 claims description 2
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 125000006239 protecting group Chemical group 0.000 claims description 2
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- 239000013543 active substance Substances 0.000 claims 2
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- 125000004432 carbon atom Chemical group C* 0.000 description 19
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical compound NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 description 12
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- 125000001183 hydrocarbyl group Chemical group 0.000 description 8
- 238000006467 substitution reaction Methods 0.000 description 8
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- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 4
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- KVBGVZZKJNLNJU-UHFFFAOYSA-N naphthalene-2-sulfonic acid Chemical compound C1=CC=CC2=CC(S(=O)(=O)O)=CC=C21 KVBGVZZKJNLNJU-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/29—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/75—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
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- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00115451 | 2000-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200300164B true ZA200300164B (en) | 2004-04-07 |
Family
ID=8169291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200300164A ZA200300164B (en) | 2000-07-18 | 2003-01-07 | Novel aniline derivatives. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6683201B2 (fr) |
| EP (1) | EP1303503B1 (fr) |
| JP (1) | JP4005911B2 (fr) |
| KR (1) | KR100594665B1 (fr) |
| CN (1) | CN1208329C (fr) |
| AR (1) | AR032623A1 (fr) |
| AT (1) | ATE456561T1 (fr) |
| AU (2) | AU2001289642B2 (fr) |
| BR (1) | BR0112609A (fr) |
| CA (1) | CA2415551C (fr) |
| DE (1) | DE60141206D1 (fr) |
| MX (1) | MXPA03000429A (fr) |
| WO (1) | WO2002006189A2 (fr) |
| ZA (1) | ZA200300164B (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60133743T2 (de) * | 2000-08-21 | 2009-07-02 | Pacific Corp. | Neue thiourea-derivate und pharmazeutische zusammensetzungen die diese enthalten |
| JP2005518376A (ja) | 2001-12-14 | 2005-06-23 | ノボ ノルディスク アクティーゼルスカブ | 化合物およびホルモン感受性リパーゼの活性を低下させるためのその使用 |
| EP1636201A1 (fr) * | 2003-06-12 | 2006-03-22 | Novo Nordisk A/S | Carbamates de phenyle para-substitues en tant qu'inhibiteurs de la lipase hormono-sensible |
| US7312248B2 (en) * | 2004-09-23 | 2007-12-25 | Schering-Plough Animal Health Corporation | Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives |
| WO2007005737A2 (fr) * | 2005-07-01 | 2007-01-11 | Case Western Reserve University | Inhibiteurs d'amine oxydase |
| CN102367260A (zh) * | 2011-12-12 | 2012-03-07 | 南京药石药物研发有限公司 | 2-氨基嘧啶-5-硼酸的合成方法 |
| US20170283445A1 (en) * | 2016-04-05 | 2017-10-05 | University Of South Carolina | Small Molecule Inhibitors Selective For Polo-Like Kinase Proteins |
| CN114484897B (zh) * | 2022-02-22 | 2022-10-11 | 吉林大学 | 一种双流道波纹板型太阳能集热器 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1055548A (en) * | 1965-08-23 | 1967-01-18 | Acraf | New substituted 1-aryl-3-aminopropynes and process for their preparation |
| EP0484378B1 (fr) * | 1989-07-25 | 1994-09-14 | The Upjohn Company | Amine-alcenyle-phenyle-alcanesulfonamides tertiaires antiarythmiques |
| GB9207855D0 (en) * | 1992-04-09 | 1992-05-27 | Ici Plc | Therapeutic amines |
| TW438774B (en) | 1993-07-14 | 2001-06-07 | Hoffmann La Roche | Pharmaceutical composition for lowering cholesterol containing phenalkylamines and certain novel phenalkylamines |
| CA2190699A1 (fr) * | 1995-12-08 | 1997-06-09 | Johannes Aebi | Amines tertiaires |
-
2001
- 2001-07-11 CA CA002415551A patent/CA2415551C/fr not_active Expired - Fee Related
- 2001-07-11 JP JP2002512096A patent/JP4005911B2/ja not_active Expired - Fee Related
- 2001-07-11 EP EP01969367A patent/EP1303503B1/fr not_active Expired - Lifetime
- 2001-07-11 CN CNB018129943A patent/CN1208329C/zh not_active Expired - Fee Related
- 2001-07-11 MX MXPA03000429A patent/MXPA03000429A/es active IP Right Grant
- 2001-07-11 AU AU2001289642A patent/AU2001289642B2/en not_active Ceased
- 2001-07-11 WO PCT/EP2001/007993 patent/WO2002006189A2/fr not_active Ceased
- 2001-07-11 BR BR0112609-1A patent/BR0112609A/pt not_active IP Right Cessation
- 2001-07-11 AT AT01969367T patent/ATE456561T1/de not_active IP Right Cessation
- 2001-07-11 KR KR1020037000752A patent/KR100594665B1/ko not_active Expired - Fee Related
- 2001-07-11 AU AU8964201A patent/AU8964201A/xx active Pending
- 2001-07-11 DE DE60141206T patent/DE60141206D1/de not_active Expired - Fee Related
- 2001-07-16 AR ARP010103374A patent/AR032623A1/es unknown
- 2001-07-16 US US09/906,214 patent/US6683201B2/en not_active Expired - Fee Related
-
2003
- 2003-01-07 ZA ZA200300164A patent/ZA200300164B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU8964201A (en) | 2002-01-30 |
| CA2415551A1 (fr) | 2002-01-24 |
| US20020038025A1 (en) | 2002-03-28 |
| CA2415551C (fr) | 2007-09-25 |
| US6683201B2 (en) | 2004-01-27 |
| AU2001289642B2 (en) | 2005-01-13 |
| JP2004504280A (ja) | 2004-02-12 |
| ATE456561T1 (de) | 2010-02-15 |
| CN1443179A (zh) | 2003-09-17 |
| AR032623A1 (es) | 2003-11-19 |
| KR20030029623A (ko) | 2003-04-14 |
| EP1303503A2 (fr) | 2003-04-23 |
| EP1303503B1 (fr) | 2010-01-27 |
| BR0112609A (pt) | 2003-07-01 |
| MXPA03000429A (es) | 2003-06-24 |
| KR100594665B1 (ko) | 2006-06-30 |
| DE60141206D1 (de) | 2010-03-18 |
| CN1208329C (zh) | 2005-06-29 |
| JP4005911B2 (ja) | 2007-11-14 |
| WO2002006189A3 (fr) | 2002-08-08 |
| WO2002006189A2 (fr) | 2002-01-24 |
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